Program - Society of Toxicology

44 th Annual Meeting
and ToxExpo
Program Description
#1261 STRUCTURAL HETEROGENEITY AT THE UDP-
GLUCURONOSYLTRANSFERASE 1A LOCUS IN
A KOREAN POPULATION. S. Yea 1,2 , W. Kim 2 , S.
Lee 2 , J. Sohn 2 , S. Oh 2 , Y. Park 1 and J. Shin 2 .
1 Department of Biochemistry, Inje University, Pusan,
Korea, South Korea and 2 PharmacoGenomics Research
Center, Inje University, Pusan, South Korea. Sponsor:
H. Kim.
#1262 ROLE OF ALCOHOL DEHYDROGENASE
GENOTYPE IN PREDICTING DEVELOPMENT
OF FETAL ALCOHOL SYNDROME (FAS). N. M.
Spiegl 1 , J. L. Powell 1 , K. S. Squibb 1 , K. A. Strauss 1 , J.
O’Kane 2 and J. D. Cook 2 . 1 Epidemiology and
Preventive Medicine, University of Maryland School of
Medicine, Baltimore, MD and 2 Medical and Research
Technology, University of Maryland School of
Medicine, Baltimore, MD.
#1263 CHARACTERIZATION OF THE VAL108MET
COMT POLYMORPHISM. A. E. Doyle 1 , B. L.
McAtee 1 , J. P. Bressler 1,2 , P. M. Silber 3 and J. D.
Yager 1 . 1 Environmental Health Sciences, Johns Hopkins
University, Baltimore, MD, 2 Kennedy-Krieger Institute,
Baltimore, MD and 3 In Vitro Technologies, Inc.,
Baltimore, MD.
#1264 POLYMORPHISM IN N-ACETYLTRANSFERASE
1 ALLELES NAT1*10 AND NAT1*14A IN
BENZIDINE-EXPOSED WORKERS IN THE
CHINESE DYESTUFF INDUSTRY: LACK OF
ASSOCIATION WITH CYTOLOGICAL
GRADING OF EXFOLIATED UROTHELIAL
CELLS. W. Guo 1 , G. Lin 1 , J. Chen 2 , K. Golka 3 and J.
Shen 1 . 1 Institute of Plant Physiology and Ecology,
Shanghai Institutes for Biological Sciences, Chinese
Academy of Sciences, Shanghai, China, 2 Municipal
Center for Disease Prevention and Control, Shanghai,
China and 3 Institute for Occupational Physiology at the
University of Dortmund, Dortmund, Germany.
#1265 INDIRECT EVIDENCE FOR EXTRAGENIC
AND/OR ENVIRONMENTAL INFLUENCE ON
HUMAN NAT1 EXPRESSION: ANALYSIS OF
PRIMARY HEPATOCYTES BY ALLELE-
SPECIFIC QUANTITATIVE REAL-TIME RT-
PCR. J. M. Walraven, D. F. Barker, M. A. Doll and D.
W. Hein. Pharmacology & Toxicology, University of
Louisville, Louisville, KY.
#1266 FUNCTIONAL CHARACTERIZATION OF
MOUSE N-ACETYLTRANSFERASES IN A NAT2
KNOCKOUT MODEL. J. A. Loehle 1 , L. Wakefield 2 ,
H. Long 2 , M. A. Doll 1 , J. R. Neale 1 , E. Sim 2 and D. W.
Hein 1 . 1 Pharmacology/Toxicology, University of
Louisville, Louisville, KY and 2 Pharmacology,
University of Oxford, Oxford, United Kingdom.
#1267 MECHANISTIC STUDY OF THE A 411 T (L137F)
GENETIC POLYMORPHISM IN HUMAN N-
ACETYLTRANSFERASE 2. Y. Zang, S. Zhao, J.
States and D. W. Hein. Pharmacology & Toxicology,
University of Louisville, Louisville, KY.
#1268 PARAOXONASE POLYMORPHISM LEU-MET55
AND ITS RELATIONSHIP TO DIABETIC
COMPLICATIONS IN PATIENTS WITH NON-
INSULIN-DEPENDENT DIABETES MELLITUS.
A. KARAKAYA. Toxicology, Ankara University,
Ankara, Turkey. Sponsor: A. Ankara University.
#1269 GSTM1, GSTM3 AND SMOKING HABITS IN
BLADDER CANCER CASES FROM TWO
DIFFERENT INDUSTRIAL AREAS. K. Golka 1 , T.
Schmidt 1 , T. Seidel 2 , H. Dietrich 2 , H. Roemer 1,3 , D.
Loehlein 3 , T. Reckwitz 4 , J. Soekeland 1,4 , R. Thier 1 and
S. Selinski 5 . 1 Institute for Occupational Physiology at
the University of Dortmund, Dortmund, Germany,
2 Department of Urology, Lutherstadt Wittenberg,
Germany, 3 Department of Surgery, Klinikum,
Dortmund, Germany, 4 Department of Urology,
Klinikum, Dortmund, Germany and 5 Department of
Statistics, University of Dortmund, Dortmund,
Germany.
#1270 GST-T1, P53, AND CASPASE-8 POLYMORPHISMS
AND COLON CANCER RISK. J. Goodman 1,2 and C.
C. Harris 2 . 1 Gradient Corporation, Cambridge, MA and
2 Laboratory of Human Carcinogenesis, National Cancer
Institute, Bethesda, MD.
#1271 THE GLUTAMATE CYSTEINE LIGASE
CATALYTIC SUBUNIT -129 C/T SINGLE
NUCLEOTIDE POLYMORPHISM IS
ASSOCIATED WITH THE LEVEL OF GAD65
AUTOANTIBODIES IN TYPE 1 DIABETES
PATIENTS WITH A DELAYED AGE-AT-ONSET. L.
M. Bekris 1 , M. Janer 2 , T. J. Kavanagh 1 and A.
Lernmark 3 . 1 Environmental and Occupational Health
Sciences, University of Washington, Seattle, WA,
2 Institute for Systems Biology, Seattle, WA and
3 Medicine, University of Washington, Seattle, WA.
#1272 BIOLOGICAL CHARACTERIZATION OF THE
MANGANESE SUPEROXIDE DISMUTASE
(MNSOD) VAL-9ALA POLYMORPHISM. B. L.
McAtee, A. E. Doyle and J. D. Yager. Environmental
Health Sciences, Johns Hopkins Bloomberg School of
Public Health, Baltimore, MD.
#1273 MOLECULAR ANALYSIS OF
DIHYDROPYRIMIDINE DEHYDROGENASE
AND THYMIDYLATE SYNTHASE GENE
POLYMORPHISMS IN A TURKISH
POPULATION. S. Suzen, N. Yuce, G. Guvenc and Y.
Duydu. Toxicology, Ankara University, Ankara, Turkey.
Sponsor: S. Suzen.
#1274 TWO POLYMORPHISMS IN THE DNA REPAIR
GENE MGMT INCREASE HUMAN SENSITIVITY
TO THE TOBACCO-SPECIFIC NITROSAMINE
NNK. C. E. Hill, A. A. Affatato, K. J. Wolfe, J. K.
Wickliffe and S. Z. Abdel-Rahman. PMCH-
Environmental Toxicology, University of Texas Medical
Branch, Galveston, TX.
#1275 ASSOCIATIONS BETWEEN MERCURY, BDNF
POLYMORPHISM, AND ATTENTIONAL
ATTRIBUTES OF MOTOR FUNCTION. D.
echeverria 1,2 , J. S. Woods 1,2 , N. J. Heyer 1 , F. M. Farin 2 ,
A. C. Bittner 1 , T. Li 2 and C. Garabedian 1 . 1 Battelle
CPHRE, Seattle, WA and 2 ENVH, U of Washington,
Seattle, WA.
TUESDAY
up-to-date information at www.toxicology.org 145