Program - Society of Toxicology

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SESSION INDEX 44 th Annual Meeting and ToxExpo Scientific Session Index (Continued) Date/Time Topic/Abstract # Room Page Wednesday * Neurotoxicity, Pesticides Exhibit Hall 196 1:30 PM #1936–1967 Sunset Sessions Date/Time Topic/Abstract # Room Page Wednesday Advances in Material Safety Data 207 198 4:30 PM Sheet Communication #1664–1668 Wednesday The Safety Assessment of 208 199 4:30 PM Nutritionally Improved Food and Feed Crops #1669–1673 Wednesday Vinyl Chloride: Legacy and 220 199 4:30 PM Lessons Learned #1674–1677 Symposia Thursday Date/Time Topic/Abstract # Room Page Thursday Cross–Species Toxicology in the RO4 200 8:30 AM Age of Genomics #1968–1973 Thursday Developmental Expression of 208 201 8:30 AM Human Phase I and Phase II Toxicant Metabolizing Enzymes: Impact on Early Life Stage Susceptibility #1978–1984 Thursday Systems Biology: Approaches and 220 201 8:30 AM Applications to Toxicology #1979–1984 Poster Sessions * Attended 8:30 AM–10:00 AM; otherwise attended 10:00 AM–11:30 AM. Date/Time Topic/Abstract # Room Page Thursday * Alternatives to Mammalian Ballroom B 203 8:30 AM Models #1996–2023 Thursday Safety Evaluation—Safety Ballroom B 205 8:30 AM Pharmacology #2024–2032 Thursday * Persistent Organic Pollutants Ballroom B 205 8:30 AM #2033–2072 Thursday Risk Assessment II #2073–2112 Ballroom B 208 8:30 AM Thursday * Renal Toxicology #2113–2142 Ballroom B 211 8:30 AM Thursday Pesticides #2143–2170 Ballroom B 213 8:30 AM Thursday * Dermal Toxicology #2171–2203 Ballroom B 215 8:30 AM Thursday Genotoxicity #2204–2236 Ballroom B 217 8:30 AM Thursday * Developmental Toxicology Ballroom B 219 8:30 AM Mechanisms #2237–2261 Thursday DNA and Protein Adducts Ballroom B 221 8:30 AM #2262–2275 Thursday * Apoptosis #2276–2303 Ballroom B 222 8:30 AM Workshops Date/Time Topic/Abstract # Room Page Thursday Cellular/Molecular Mechanisms RO8 202 8:30 AM Involved in Environmental Chemicals —Induced Dopaminergic Neurotocivity and the Consequences on Neurodegenerative Diseases #1985–1989 Thursday Safety Assessment of Biological RO6 203 8:30 AM Therapeutic Products—Defining the Scientific and Regulatory Issues #1990–1995 38 SOT's 44 th Annual Meeting
44 th Annual Meeting and ToxExpo Continuing Education The Continuing Education Program offers a wide range of courses that cover state-of-the-art knowledge in toxicology, as well as new developments in toxicology and related disciplines. Courses can be applied toward certifying and licensing board requirements and may also be used for recertification with the American Board of Toxicology (ABT). Both basic and advanced course topics are offered. The basic course is intended to provide a broad overview of an area or to assist individuals in learning new techniques or approaches. The advanced course is intended to be of interest to individuals with previous knowledge of the subject or already working in the field. Please Note: Each Continuing Education Course is offered in one of three time blocks: Sunrise (7:00 AM–7:45 AM), AM (8:15 AM–12:00 NOON) or PM (1:15 PM–5:00 PM). Check the signage in the SOT registration area for room assignments. *The Primary Specialty Section (SS) or Regional Chapter (RC) Endorser FUNDAMENTALS OF NANOTECHNOLOGY: CHEMISTRY, EXPOSURE, HEALTH/ ENVIRONMENTAL ASSESSMENTS AND SOCIETAL IMPACTS SUNRISE MINI-COURSE 1 BASIC Chairperson(s): David B. Warheit, DuPont Haskell Laboratory, Newark, DE. Endorsed by: Ethical Legal and Social Issues SS Inhalation SS* Occupational and Public Health SS Risk Assessment SS Nanotechnology is an emerging multidisciplinary science that deals with the creation and use of molecules a few billionths of a meter in size. Assessing the potential hazards of the nanomaterials in this technology, and the products constructed from nanoparticulates is an emerging area in toxicology and health risk assessment. The development of toxicity data sets and exposure assessments for various nanoparticles and nanomaterials is ongoing and evolving as new particles, materials and exposure methodologies are developed. A related issue in toxicology and risk assessment is the extent to which nanoparticle toxicity can be extrapolated from existing toxicology databases for macro and microscale particle-types. Additional information needs that are being addressed include the environmental and biological fate, transport, persistence, and transformation, as well as the recyclability and overall sustainability of manufactured nanoparticles. This sunrise lecture is designed to be a basic primer on the fundamental chemistry and physics of engineered nanostructures. The understanding of the composition of and source generation of particles becomes fundamentally more important when one considers that the surfaces or surface coatings may comprise > 50% composition of small nanoparticles (< 30 nm), and herein will lie the interactions of nanoparticles with cells. Future studies likely will demonstrate that method of particle synthesis, surface coatings, aggregation potential, surface charge, and shape may be as or more important than particle size in modifying biological/toxicological effects. Methods to form materials such as single-walled carbon nanotubes, fullerenes, quantum dots, nanocrystalline ceramics (e.g., titania), and nanometals will be reviewed. For each material class, the essential properties and applications will be outlined. The tutorial will conclude with a discussion of the actual applications of these high performance materials and projections for the industry growth over the next decade. • The Basics of Engineered Nanomaterials for Toxicologists or Tutorial: The Fundamental Chemistry and Physics of Engineered Nanostructures, Vicki L. Colvin, Rice University, Houston, TX. DOSE CONSIDERATIONS FOR IN VITRO STUDIES OF AIR POLLUTANT TOXICITY AM 02 BASIC Chairperson(s): John B. Morris, University of Connecticut, Storrs, CT, and JeanClare Seagrave, Lovelace Respiratory Research Institute, Albuquerque, NM. Endorsed by: In Vitro SS Inhalation SS* Risk Assessment SS Student Advisory Committee Technological advances have made possible the investigation of the cellular effects of air pollutants through variety of in vitro approaches. However, in order to be relevant to human health effects following ambient exposures, these methods must accurately model biologically relevant exposure pathways, doses and responses. This continuing education course will provide both theoretical and practical information on appropriate dose selection and dosage techniques for in vitro studies of air pollutant toxicity. The first presentation will cover the basic concepts of vapor dosimetry including the roles of partitioning, chemical reactivity and local metabolism. Specific information on regional respiratory deposition in laboratory animals and humans and its relevance to cellular microdosimetry will be provided. The second presentation will include specific examples of in vitro approaches with a focus on microdosimetric considerations for reactive gases; in particular the potential biological impacts of surface lining layers and their constituents will be emphasized. Basic concepts of size specific regional particle deposition and clearance will be covered in the third presentation. Specific information on regional respiratory deposition efficiencies in laboratory animals and humans and its relevance to cellular microdosimetry will be provided. The final presentation will describe specific examples of in vitro approaches on particle toxicity with a cellular dosimetric comparison of effects observed in vitro compared to those in vivo. Overall the course is aimed at providing information not only on the importance of employing in vivo dosimetric considerations in designing in vitro studies, but also with providing a firm conceptual foundation for the selection of relevant doses for such work. • Dosimetric Considerations for Vapors and Gases, John B. Morris, University of Connecticut, Storrs, CT. • In Vitro Systems for Studies of Reactive Gases, Edward Postlethwait, University of Alabama at Birmingham, Birmingham, AL. • Dosimetric Considerations for Particles, Richard B. Schlesinger, Pace University, Pleasantville, NY. • In Vitro Systems for Studies of Particles, JeanClare Seagrave, Lovelace Respiratory Research Institute, Albuquerque, NM. CE up-to-date information at www.toxicology.org 39
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Page 3 and 4: Contents Program Overview .........
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Page 29 and 30: 2005 Award Winners The Society of T
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Page 47 and 48: INTERNATIONAL HARMONIZATION OF TECH
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Program - Society of Toxicology

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