Program - Society of Toxicology

44 th Annual Meeting
and ToxExpo
Program Description
#68 ROLE OF VASCULAR ENDOTHELIAL GROWTH
FACTOR (VEGF) IN ACETAMINOPHEN
HEPATOTOXICITY. B. Donahower 1 , S. S.
McCullough 2 and L. P. James 3,2 . 1 Pharmacology,
University of Arkansas For Medical Sciences, Little
Rock, AR, 2 Toxicology, University of Arkansas For
Medical Sciences, Little Rock, AR and 3 Arkansas
Children’s Hospital Research Institute, Little Rock, AR.
Sponsor: J. Hinson.
#69 LIPOPOLYSACCHARIDE POTENTIATES
ACETAMINOPHEN HEPATOTOXICITY. S. W.
Newport, C. M. Dugan, X. Deng, P. E. Ganey, R. A.
Roth and J. F. Maddox. Pharmacology and Toxicology,
National Food Safety and Toxicology Center, Michigan
State University, East Lansing, MI.
#70 POTENTIATION OF 3-(3, 5-
DICHLOROPHENYL)-2, 4-
THIAZOLIDINEDIONE (DCPT)-INDUCED
HEPATOTOXICITY IN RATS BY
DEXAMETHASONE (DEX) PRETREATMENT. C.
M. Crincoli, N. N. Patel, R. Tchao and P. J. Harvison.
Department of Pharmaceutical Sciences, University of
the Sciences in Philadelphia, Philadelphia, PA.
#71 PROTECTIVE EFFECT OF DIBROMOACETATE
IN PRIMARY HEPATOCYTE CULTURES. J. M.
McMillan and K. McKelvey. Pharmacology, Medical
University of South Carolina, Charleston, SC.
#72 NICOTINAMIDE ALTERATION OF
BROMOBENZENE-INDUCED
HEPATOTOXICITY. K. W. Hall 1 , P. C. Grivas 1 , C.
Muro-Cacho 2 and R. D. Harbison 1,2 . 1 Toxicology,
University of South Florida, Tampa, FL and 2 Pathology,
College of Medicine, University of South Florida,
Tampa, FL.
#73 COLCHICINE ANTIMITOSIS ABOLISHES
SUBCHRONIC CHLOROFORM-INDUCED
PROTECTION AGAINST LETHAL DOSE OF
CHLOROFORM. B. K. Philip 1 , S. S. Anand 2 , P. S.
Palkar 1 , M. M. Mumtaz 3 , J. R. Latendresse 4 and H. M.
Mehendale 1 . 1 Department of Toxicology, University of
Louisiana at Monroe, Monroe, LA, 2 University of
Georgia, Athens, GA, 3 ATSDR, CDC, Chamblee, GA
and 4 NCTR, Jefferson, AR.
#74 UNDERNUTRITION FAILS TO EXACERBATE
ALCOHOL-INDUCED LIVER DAMAGE
DESPITE EVIDENCE OF INCREASED
OXIDATIVE STRESS. J. N. Baumgardner 1,2 , B. N.
Yarberry 2 , J. V. Badeaux 2 , M. Hidestrand 1,2 , K.
Shankar 1,2 , T. M. Badger 2,3 and M. J. Ronis 1,2 .
1 Pharmacology and Toxicology, University of Arkansas
for Medical Sciences (UAMS), Little Rock, AR,
2 Arkansas Children’s Nutrition Center, Little Rock, AR
and 3 Physiology and Biophysics, UAMS, Little Rock,
AR.
#75 RESILIENCY OF AGED FISCHER 344 RATS TO
CHLORDECONE-AMPLIFIED CARBON
TETRACHLORIDE TOXICITY. H. M. Mehendale,
B. Murali and M. C. Korrapati. Toxicology, University
of Louisiana at Monroe, Monroe, LA.
#76 PENTOXIFYLLINE AND ANTI-TUMOR
NECROSIS FACTOR α ANTIBODIES ARE
UNABLE TO PROTECT MICE FROM
FUMONISIN HEPATOTOXICITY. Q. He and R. P.
Sharma. The University of Georgia, Athens, GA.
#77 CALPASTATIN OVER-EXPRESSION PROTECTS
AGAINST TOXICANT-INDUCED PROGRESSION
OF INJURY ASSOCIATED WITH ACUTE LIVER
FAILURE IN MICE. P. B. Limaye 1 , V. S. Bhave 1 , P. S.
Palkar 1 , J. R. Latendresse 2 , S. Yu 3 , J. K. Reddy 3 and H.
M. Mehendale 1 . 1 Toxicology, University of Louisiana at
Monroe, Monroe, LA, 2 NCTR, Jefferson, AR and
3 Northwestern University, Chicago, IL.
#78 IMPAIRED HEPATIC REGENERATION IN
METALLOTHIONEIN KNOCKOUT MICE
AFTER PARTIAL HEPATECTOMY. J. R. Oliver
and G. Cherian. Pathology, University of Western
Ontario, London, ON, Canada.
#79 THE ROLE OF GLUTATHIONE DEPLETION
AND OXIDATIVE STRESS ON CYTOTOXICITY
OF CHROMIUM (VI) IN ISOLATED RAT
HEPATOCYTES. O. S. El-Tawil 1 , A. M. Mohamadin 2
and A. H. Abou-Hadeed 3 . 1 Toxicology and Forensic
Medicine, Faculty of Veterinary Medicine, Cairo
University, Cairo, Egypt, 2 Department of Biochemistry,
Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt
and 3 Department of Forensic Medicine and Toxicology,
Faculty of Veterinary Medicine, Zagazig University,
Zagzig, Egypt.
#80 ANTI-HYPERCHOLESTEROLEMIA DRUGS IN
THE STATIN CLASS REDUCE GLUTATHIONE
LEVELS AND INCREASE CASPASE 3
ACTIVATION IN AN IN VITRO CELL MODEL. J.
F. Pregenzer, J. M. McKim, Jr., P. C. Wilga and D. K.
Petrella. CeeTox, Kalamazoo, MI.
#81 EFFECT OF THIAZOLIDINEDIONE (TZD) RING
MODIFICATION ON 3-(3, 5-
DICHLOROPHENYL)-2, 4-
THIAZOLIDINEDIONE (DCPT) INDUCED
HEPATOTOXICITY IN RATS. N. N. Patel, C. M.
Crincoli, R. Tchao and P. J. Harvison. Department of
Pharmaceutical Sciences, University of the Sciences in
Philadelphia, Philadelphia, PA.
#82 ENDOGENOUS FATTY ACID METHYL ESTERS
AS A POTENTIAL MARKER OF HUMAN
HEPATOCELLULAR CARCINOMA. S. H. Khan, B.
S. Kaphalia and G. Ansari. Pathology, UTMB,
Galveston, TX.
#83 AN INVESTIGATION INTO THE
RELATIONSHIP OF VITAMIN A LEVELS AND
HEPATITIS, HYPERPLASIA, BENIGN OR
MALIGNANT LESIONS IN RODENT LIVERS. C.
Bray. Covance Laboratories Ltd., Harrogate, United
Kingdom. Sponsor: D. Everett.
MONDAY
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