Program - Society of Toxicology

44 th Annual Meeting
and ToxExpo
Program Description
#974 NEONATAL EXPOSURE TO NICOTINE
INDUCES INCREASED SUSCEPTIBILITY TO
PARAOXON EXPOSURE AT ADULT AGE. E.
Ankarberg, A. Fredriksson and P. Eriksson. Department
of Environmental Toxicology, Uppsala University,
Uppsala, Sweden.
#975 NEONATAL EXPOSURE TO A SINGLE LOW
DOSE OF A TYPE I PYRETHROID
(BIOALLETHRIN) AFFECTS SPONTANEOUS
BEHAVIOR AND LEARNING IN ADULT MICE
OF DIFFERENT STRAINS. C. Fischer, A.
Fredriksson and P. Eriksson. Department of
Environmental Toxicology, Uppsala University,
Uppsala, Sweden.
#976 STRUCTURAL IMPACT OF DIAZINON AND
MOLINATE ON NEURITE OUTGROWTH IN
N1E-115 CELLS. D. T. Edge 1 , R. D. Cannady 2 , J. S.
Ross 2 , A. Umantsev 2 and S. L. Chao 2 . 1 Department of
Chemistry, North Carolina State University, Raleigh,
NC and 2 Department of Natural Sciences, Fayetteville
State University, Fayetteville, NC. Sponsor: J. Casida.
#977 NEUROPATHOLOGICAL FINDINGS IN
DEVELOPMENTAL NEUROTOXICITY
TESTING: COMPARISON OF QUALITATIVE
AND QUANTITATIVE EVALUATIONS. K.
Raffaele 1 , W. Sette 2 , J. Doherty 1 , S. Makris 1 and K.
Crofton 3 . 1 OPP, U.S. EPA, Washington, DC, 2 OSA, U.S.
EPA, Washington, DC and 3 NHEERL, ORD, U.S. EPA,
Research Triangle Park, NC.
#978 A SIMPLE METHOD TO ESTIMATE RAT PUP
EXPOSURE IN DIETARY DEVELOPMENTAL
NEUROTOXICITY STUDIES. M. L. Weiner 1 , J. D.
McCarty 1 , A. Chen 1 , M. Nemec 2 , G. Schaefer 2 and J.
Buelke-Sam 3 . 1 Toxicology, FMC Corporation,
Princeton, NJ, 2 WIL Research Laboratories, Ashland,
OH and 3 Toxicology Services, Greenfield, IN.
#979 THALIDOMIDE-INDUCED OXIDATIVE STRESS
IN RAT DORSAL ROOT GANGLIA (DRG) CELL
CULTURES. R. Roman Gomez 1 , C. A. Flynn 1 , T. L.
Builee 1 , P. A. Paximadis 1 , J. M. Hansen 2 , M. A.
Philbert 1 and C. Harris 1 . 1 Environmental Health
Sciences, University of Michigan, Ann Arbor, MI and
2 Biochemistry, Emory University, Atlanta, GA.
#980 EFFECTS OF DEVELOPMENTAL
HYPOTHYROIDISM INDUCED BY PTU ON
BRAIN FUNCTION IN RATS. R. Tsuji, K.
Kobayashi, T. Yoshioka, M. Sasaki, M. kushida, S.
Yabushita, T. Mino and T. Seki. Sumitomo Chemical
Co., Ltd., Environmental Health Science Laboratory,
Osaka, Japan. Sponsor: T. Yamada.
#981 EFFECT OF HYPOTHYROIDISM INDUCED BY
PERINATAL EXPOSURE TO PTU ON
CEREBELLAR GENE EXPRESSION. K. kobayashi,
R. Tsuji, T. Yoshioka, M. Kushida, T. Mino and T. Seki.
Sumitomo Chemical Co., Ltd.,, Osaka, Japan. Sponsor:
T. Yamada.
#982 GABERGIC FUNCTION IS ALTERED
FOLLOWING DEVELOPMENTAL
HYPOTHYROIDISM: NEUROANATOMICAL
AND NEUROPHYSIOLOGICAL EVIDENCE. M.
E. Gilbert 1 , L. Sui 1,2 , S. Thomas 3 , S. Smoller 3 , J.
Schon 3 and J. Goodman 3 . 1 Neurotoxicology, U.S. EPA,
Research Triangle Park, NC, 2 NRC, Washington, DC
and 3 CNRRR, Helen Hayes Hosp, W Haverstraw, NY.
#983 VITAMIN E PROTECTS AGAINST THE
BEHAVIORAL DEFICITS PRODUCED BY
NEONATAL SODIUM VALPROATE EXPOSURE
IN MICE. A. K. Halladay 1,3 , G. C. Wagner 2,3 , X.
Ming 3 and K. R. Reuhl 1,3 . 1 Pharmacology &
Toxicology, Rutgers University, Piscataway, NJ,
2 Psychology, Rutgers University, Piscataway, NJ and
3 Center for Childhood Neurotoxicology & Exposure
Assessment, UMDNJ, New Brunswick, NJ.
#984 CAMPTOTHECIN-INDUCED APOPTOSIS IN
NEURAL STEM CELLS AND DIFFERENTIATED
CULTURES THROUGH TWO DIFFERENT
MECHANISMS. J. Li, M. L. Spletter and J. A.
Johnson. University of Wisconsin at Madison, Madison,
WI.
#985 THE ROLE OF AMYLOID-β AND α-SECRETASE
CLEAVED AMYLOID PRECURSOR PROTEIN
ON NEUROGENESIS IN ADULT HUMAN
NEOCORTICAL SLICE CULTURES. J. Kim 1 , T. D.
Stein 2 , N. J. Anders 1 and J. A. Johnson 1,2,3 . 1 School of
Pharmacy, University of Wisconsin-Madison, Madison,
WI, 2 Neuroscience Training Program, University of
Wisconsin-Madison, Madison, WI and 3 Waisman
Center, University of Wisconsin-Madison, Madison, WI.
#986 BISPHENOL-A, AN ENVIRONMENTAL
CONTAMINANT THAT ACTS AS A THYROID
HORMONE RECEPTOR ANTAGONIST IN
VITRO, INCREASES SERUM THYROXINE AND
ALTERS RC3/NEUROGRANIN EXPRESSION IN
THE DEVELOPING RAT BRAIN. R. Bansal and C.
Parris. Biology, University of Massachusetts, Amherst,
MA. Sponsor: R. Zoeller.
#987 EXPOSURE OF RHESUS MONKEYS TO
COCAINE THROUGHOUT GESTATION
RESULTS IN DECREASED SENSITIVITY TO
COCAINE IN ADULTHOOD: EFFECTS OF
COCAINE ON TIMING BEHAVIOR. M. G.
Paule 1,3 , M. P. GIllam 1 , S. A. Graham 3 and J. J.
Chelonis 2,3,1 . 1 Division of Neurotoxicology, National
Center for Toxicological Research, Jefferson, AR,
2 Graduate School, University of Arkansas at Little
Rock, Little Rock, AR and 3 Pediatrics, Arkansas
Children’s Hosptal, Little Rock, AR.
#988 OBSERVATION OF CATECHOLAMINERGIC
NEURONS IN THE FETAL RAT BRAIN
EXPOSED TO THE GENOTOXIC COMPOUND,
5-BROMO-2’-DEOXYURIDINE (BRDU). T.
Ogawa 1 , M. Kuwagata 1,2 , K. T. Muneoka 1 and S.
Shioda 1 . 1 Anatomy, Showa University School of
Medicine, Tokyo, Japan and 2 Hatano Research Institute,
Kanagawa, Japan.
TUESDAY
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