Program - Society of Toxicology

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44 th Annual Meeting and ToxExpo Program Description WEDNESDAY #1373 10:50 IDENTIFYING CANDIDATES FOR THE CDM GENE, WHICH CONFERS RESISTANCE TO CADMIUM-INDUCED TESTICULAR DAMAGE IN MICE. L. Martin 1 , H. Allayee 2 , D. Shih 3 , G. Lee 1 , D. Hovland 4 , R. Hess 5 , K. Carnes 5 , R. M. Cantor 3,6 , A. J. Lusis 3 and M. Collins 1 . 1 Molecular Toxicology, UCLA, LA, CA, 2 Institute for Genetic Medicine, USC, LA, CA, 3 Human Genetics, UCLA, LA, CA, 4 5 Toxicology, Amgen, Thousand Oaks, CA, Veterinary Biosciences, University of Illinois, Urbana, IL and 6 Pediatrics, UCLA, LA, CA. Sponsor: O. Hankinson. #1374 11:10 PERIPUBERTAL DEHP EXPOSURE INHIBITS ANDROGEN-DEPENDENT DEVELOPMENT IN SPRAGUE-DAWLEY RATS. N. Noriega, J. Furr, C. Lambright, V. S. Wilson and L. E. Gray. RTD, U.S. EPA ORD NHEERL, Research Triangle Park, NC. Wednesday Morning, March 9 8:30 AM to 11:30 AM Room RO6 2 GeneGo, Inc., St. Joseph, MI. #1379 #1380 #1381 #1382 #1383 9:50 10:10 10:30 10:50 11:10 PREDICTION OF HEPATOCARCINOGENICITY OF CHEMICALS USING THE GENE EXPRESSION IN THE 28-DAY REPEAT-DOSE TOXICITY STUDY. H. Matsumoto 1 , F. Saito 1 , Y. Yoshikuni 1 , Y. Sudo 1 , M. Otsuka 1 , H. Miyaura 1 , I. Fukuda 5 , K. Saito 2 , K. Sumida 2 , M. Sekijima 3 , K. Nakayama 3 and T. Shirai 4 . 1 Chemicals Evaluation and Research Institute, Japan, Tokyo, Japan, 2 Sumitomo Chemical Co., Ltd.,, Osaka, Japan, 3 Mitsubishi Chemical Safety Institute Ltd.,, Ibaraki, Japan, 4 Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan and 5 Mitsui Knowledge Industry Co., Ltd.,, Tokyo, Japan. TOXICOGENOMICS FOCUSING ON THE HEMOPOIETIC STEM CELL TOXICOLOGY. Y. Hirabayashi 1 , B. Yoon 1 , K. Kitada 2 , T. Matsushita 1,3 , K. Kobayashi 2 , K. Igarashi 1 , Y. Kodama 1 , J. Kanno 1 and T. Inoue 4 . 1 Division of Cellular & Molecular Toxicology, National Institute of Health Sciences, Tokyo, Japan, 2 Kamakura Research Labs, Chugai Pharmaceutical, Co., Ltd.,, Kamakura, Japan, 3 Fuji Gotenba Research Labs, Chugai Pharmaceutical, Co., Ltd.,, Shizuoka, Japan and 4 Center for Biological Safety & Research, National Institute of Health Sciences, Tokyo, Japan. QC METRICS AND THRESHOLDS FOR ASSESSING THE OVERALL QUALITY OF A MICROARRAY STUDY. L. Shi 1 , W. Tong 1 , F. Goodsaid 2 , F. Frueh 2 , F. C. Fuscoe 1 and D. A. Casciano 3 . 1 Division of Systems Toxicology, NCTR, U.S. FDA, Jefferson, AR, 2 Office of Clinical Pharmacology and Biopharmaceutics, CDER, U.S. FDA, Rockville, MD and 3 Office of the Director, NCTR, U.S. FDA, Jefferson, AR. PROTOCOLS FOR THE ASSURANCE OF MICROARRAY DATA QUALITY AND PROCESS CONTROL. L. D. Burgoon 1,5,6 , J. E. Eckel-Passow 3 , C. Gennings 4 , D. R. Boverhof 2,5,6 , J. W. Burt 2,5,6 , C. J. Fong 2,5,6 and T. R. Zacharewski 2,5,6 . 1 Pharmacology & Toxicology, Michigan State University, East Lansing, MI, 2 Biochemistry & Molecular Biology, Michigan State University, East Lansing, MI, 3 Health Sciences Research, Mayo Clinic Cancer Center, Rochester, MN, 4 Biostatistics, Virginia Commonwealth University, Richmond, VA, 5 National Food Safety and Toxicology Center, Michigan State University, East Lansing, MI and 6 Center for Integrative Toxicology, Michigan State University, East Lansing, MI. DBZACH: A COMPREHENSIVE TOXICOGENOMIC INFORMATION MANAGEMENT AND KNOWLEDGE DISCOVERY SYSTEM. R. Aiyar 2,3,4 , L. D. Burgoon 1,3,4 , P. C. Boutros 2,3,4 , E. Dere 2,3,4 , S. Doran 2,3,4 , S. S. Pai 2,3,4 , J. Vakharia 2,3,4 , R. Rotman 2,3,4 , A. Adams 2,3,4 , B. Lau 2,3,4 , R. Patel 2,3,4 and T. R. Zacharewski 2,3,4 . 1 Pharmacology & Toxicology, Michigan State University, East Lansing, MI, 2 Biochemistry & Molecular Biology, Michigan State University, East Lansing, MI, 3 National Food Safety & Toxicology Center, Michigan State University, East Lansing, MI and 4 Center for Integrative Toxicology, Michigan State University, East Lansing, MI. PLATFORM SESSION: TOXICOGENOMICS: ROLE IN PREDICTIVE TOXICOLOGY AND CARCINOGENICITY Chairperson(s): Alema Galijativic, Merck &Co., Inc., West Point, PA and Supratim Choudhary, U.S. FDA, College Park, MD. #1375 8:30 GENE ONTOLOGY MAPPING OF EARLY TRANSCRIPTIONAL RESPONSES ASSOCIATED WITH HEPATOCYTE PROLIFERATION IN THE LIVER OF DIETHYLHEXYLPHTHALATE- EXPOSED MICE. R. Currie 1 , V. Bombail 1 , D. J. Moore 1 , F. Lim 1 , J. Oliver 1 , K. Chipman 2 , I. Kimber 1 , G. Orphanides 1 and J. Moggs 1 . 1 Syngenta CTL, Macclesfield, Cheshire, United Kingdom and 2 University of Birmingham, Birmingham, United Kingdom. #1376 8:50 COMPARATIVE ANALYSIS OF GENE NETWORKS AT MULTIPLE DOSES AND TIME POINTS IN LIVERS OF RATS EXPOSED TO ACETAMINOPHEN. H. Sone 1,2 , H. Toyoshiba 1,2 , T. Yamanaka 1 , F. Parham 1 , R. Irwin 1 , G. Boorman 1 and C. J. Portier 1 . 1 ETP, NIEHS, Research Triangle Park, NC and 2 Environmental Health Sciences Division, NIES, Tsukuba, Ibaraki, Japan. #1377 9:10 A SIGNATURE GENE NETWORK APPROACH TO TOXICITY. S. Ekins 1 , C. Giroux 2 , Y. Nikolsky 1 , A. Bugrim 1 and T. Nikoskaya 1 . 1 GeneGo Inc., St Joseph, MI and 2 Institute of Environmental Health Sciences, Wayne State University, Detroit, MI. #1378 9:30 A GENETIC NETWORK APPROACH TO COMPARATIVE TOXICOGENOMICS AND RISK ASSESSMENT: THE OXIDATIVE STRESS RESPONSE. C. N. Giroux 1 , S. Ekins 2 , J. Fan 1 , I. Abdullah 1 , Y. Nikolsky 2 , A. Bugrim 2 and T. Nikolskaya 2 . 1 Institute of Environmental Health Sciences, Wayne State University, Detroit, MI and 156 SOT’s 44 th Annual Meeting
44 th Annual Meeting and ToxExpo Program Description Wednesday Morning, March 9 9:30 AM to 12:30 PM Exhibit Hall POSTER SESSION: FOOD SAFETY AND NUTRITION TOXICOLOGY I Chairperson(s): Debasis Bagchi, Interhealth Research Center, Benicia, CA and Kulbir Bakshi, National Research Council, Washington, DC. Displayed: 9:30 AM–12:30 PM Attended: 9:30 AM–11:00 AM #1384 LEVAMISOLE RESIDUES IN CHICKEN TISSUES AND EGGS. H. El-Kholy and B. W. Kemppainen. Anatomy, Physiology, Pharmacology, Auburn University, Auburn, AL. #1385 FUMONISIN B-GLUCOSE REACTION PRODUCTS ARE LESS TOXIC WHEN FED TO SWINE. G. E. Fernandez 1 , G. D. Osweiler 1 , P. A. Murphy 1 , M. Yaeger 1 , G. Rottinghaus 2 , S. Hendrich 1 and L. Buckley 1 . 1 Toxicology, Iowa State University, Ames, IA and 2 Veterinary Diagnostic Lab., University of Missouri, Columbia, MO. #1386 THE NATIONAL RESIDUE PROGRAM AS A FOOD SAFETY TOOL. J. Vodela 1 , P. Zervos 2 , C. Deyrup 3 , R. Sutton 4 , M. O’Keefe 5 , D. Pagan- Rodriguez 6 and H. Walker 7 . 1 Residue Branch, USDA/FSIS, Washington, DC, 2 Residue Branch, USDA, Washington, DC, 3 Residue Branch, USDA, Washington, DC, 4 Residue Branch, USDA, Washington, DC, 5 Residue Branch, USDA, Washington, DC, 6 7 Residue Branch, USDA, Washington, DC and Residue Branch, USDA, Washington, DC. #1387 ASSESSMENT OF METALS CONCENTRATIONS IN SALMONBERRIES AND SOURDOCK COLLECTED NEAR A MINING TRANSPORT ROAD IN NORTHWEST ALASKA. M. Garry 1,2 , S. S. Shock 2 , L. J. Yost 2 , J. Kulas 3 and W. J. Shields 2 . 1 U of Wash., Seattle, WA, 2 Exponent, Bellevue, WA and 3 Teck Cominco, Anchorage, AK. #1388 LACK OF EFFECTS OF BETA-CAROTENE DERIVED FROM BLAKESLEA TRISPORA, A NATURAL FOOD COLOR, IN A THIRTEEN- WEEK ORAL TOXICITY STUDY IN F344 RATS. K. Nabae 1 , T. Ichihara 1,2 , A. Hagiwara 1 , M. Kawabe 1 , M. Nishino 3 , T. Ogasawara 3 , Y. Sasaki 3 , M. Nakamura 3 and T. Shirai 2 . 1 Daiyu-Kai Institute of Medical Science, Inc., Ichinomiya, Japan, 2 Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan and 3 San-Ei Gen F.F.I., Inc., Toyonaka, Japan. #1389 DEPLETION OF T CELLS BY MONOCLONAL ANTIBODIES AGAINST MTHY-1.2 ANTIGEN REDUCES FUMONISIN B 1 TOXICITY IN MICE. N. Sharma, Q. He and R. P. Sharma. Physiology and Pharmacology, university of Georgia, athens, GA. #1390 SAFETY EVALUATION OF A NEW ANTI- STALING AMYLASE ENZYME FOR BAKERY APPLICATIONS. Q. Q. Bui 1 , H. V. Thygesen 2 , L. S. Bollen 3 , Z. El-Salanti 3 and C. N. Edwards 3 . 1 Genencor International, Palo Alto, CA, 2 Danisco A/S, Copenhagen, Denmark and 3 Scantox A/S, Lille Skensved, Denmark. #1391 TIME- AND DOSE-DEPENDENT CHANGES IN SPHINGOID BASE 1 PHOSPHATES IN TISSUES FROM RATS FED DIETS CONTAINING FUMONISINS. R. T. Riley, J. L. Showker and K. A. Voss. Toxicology and Mycotoxin Research Unit, USDA- ARS, Athens, GA. #1392 TOXICOLOGY STUDIES ON ALLANBLACKIA SEED OIL. L. J. Lea and S. O’Hagan. Safety and Environmental Assurance Centre, Unilever, Bedford, United Kingdom. Sponsor: P. Hepburn. #1393 SAFETY AND EFFICACY POTENTIAL OF A NOVEL ANTHOCYANIN-RICH MULTIPLE BERRY EXTRACT IN IN VIVO MODELS. M. Bagchi 1 , D. Bagchi 1,2 and C. Sen 3 . 1 InterHealth Research Center, Benicia, CA, 2 Creighton Medical Center, Omaha, NE and 3 , Ohio State Medical Center, Columbus, OH. #1394 A 90-DAY DIETARY TOXICITY STUDY OF HEATED DAG OIL AND HEATED TG OIL IN RATS. C. P. Chengelis 1 , J. B. Kirkpatrick 1 , W. B. Lawrence 1 , O. Morita 2 , Y. Tamaki 2 and H. Suzuki 2 . 1 WIL Research Laboratories, Inc., Ashland, OH and 2 Kao Corporation, Haga Tochigi, Japan. #1395 ACCUMULATION OF SPHINGOID BASES AND SPHINGOID BASE 1-PHOSPHATES: A POSSIBLE MECHANISM FOR FUSARIUM VERTICILLIOIDES CORN-SEEDLING DISEASE. L. D. Williams 1,2 , A. E. Glenn 2 , C. W. Bacon 2 , M. A. Smith 1 and R. T. Riley 2 . 1 Environmental Health Sciences, UGA, Athens, GA and 2 TMRU, USDA, Athens, GA. #1396 DEVELOPMENTAL TOXICITY OF DIETS CONTAINING FUMONISIN B 1 TO LM/BC AND CD1 MICE: A COMPARATIVE STUDY. K. A. Voss 1 , J. B. Gelineau-van Waes 2 , R. T. Riley 1 , T. D. Burns 3 and C. W. Bacon 1 . 1 Toxicology & Mycotoxin Research Unit, USDA-Agricultural Research Service, Athens, GA, 2 Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE and 3 Interdisciplinary Program in Toxicology, University of Georgia, Athens, GA. #1397 A 90-DAY DIETARY STUDY ON CARRAGEENAN WITH EMPHASIS ON THE GASTROINTESTINAL TRACT. D. C. Nuber 1 , M. L. Weiner 1 , W. Blakemore 1 , J. F. Harriman 2 and S. M. Cohen 3 . 1 Toxicology, FMC Corporation, Princeton, NJ, 2 Toxicology, WIL Research Laboratories, Ashland, OH and 3 University of Nebraska Medical Center, Omaha, NE. WEDNESDAY up-to-date information at www.toxicology.org 157
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Contents Program Overview .........
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Annual Meeting Events Calendar (Con
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Sheraton Hotel Map 44 th Annual Mee
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Itinerary Planner Computer Stations
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2005 Exhibitors (Continued) 44 th A
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General Information 44 th Annual Me
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2005 Award Winners The Society of T
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2004 Student Award Winners Colgate-
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INTERNATIONAL HARMONIZATION OF TECH
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Saturday Afternoon, March 5 2:00 PM
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SOT Affiliates for 2005 44 th Annua
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Headquarters Staff 44 th Annual Mee
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Program - Society of Toxicology

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