Program - Society of Toxicology

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44 th Annual Meeting and ToxExpo Program Description TUESDAY #1093 NORMAL VISUAL CONTRAST SENSITIVITY (VCS) AND COLOR VISION OF ADULTS AND SCHOOL-AGE CHILDREN FOUR TO FIVE YEARS AFTER EXPOSURE TO PERCHLOROETHYLENE (PERC). K. A. Mazor 1 , R. L. Shultz 2 , M. Meldrum 1 , E. Lewis-Michl 1 , L. Gensburg 1 and J. E. Storm 1 . 1 Department of Health, New York State, Troy, NY and 2 Cornea Consultants of Albany, Slingerlands, NY. #1094 NEW ASSESSMENT OF NEUROBEHAVIORAL CHANGES USING FUNCTIONAL OBSERVATIONAL BATTERY (FOB) IN MONKEYS. T. yoshikawa, Y. Deguchi, R. Anraku, K. Fukuzaki, G. Kito and R. Nagata. shin Nippon Biomedical Laboratories, Ltd., (SNBL), Yoshida, Kagoshima, Japan. #1095 NEUROBEHAVIORAL ASSESSMENT OF SIX NEUROTOXICANTS IN MALE SPRAGUE- DAWLEY RATS. K. Steinmetz, L. Rausch, A. Robb, G. Ganem, D. Lau, D. Middaugh and J. Mirsalis. SRI Int, Menlo Park, CA. #1096 ASSESSMENT OF NEUROTOXICITY USING ZEBRAFISH AS A MODEL ORGANISM. N. Roy, C. Ton, Y. Lin and C. Parng. Phylonix Pharmaceuticals, Inc., Cambridge, MA. Sponsor: D. Monteith. #1097 SENSITIVE DETECTION OF BEHAVIORAL IMPAIRMENTS IN MODERATELY LESIONED MPTP MICE BY AUTOMATED GAIT ANALYSIS. T. Guillot 1 , J. R. Richardson 1,2 and G. W. Miller 1,2 . 1 Center for Neurodegenerative Disease, Atlanta, GA and 2 2Environmental and Occupational Health, Rollins School of Public Health, Atlanta, GA. #1098 ALTERATIONS OF GENE EXPRESSION IN MICE INDUCED BY MPTP ADMINISTRATION: APPLICATION OF MICROARRAY ANALYSIS. Z. A. Xu 1 , D. R. Cawthon 1 , T. Han 2 , T. A. Patterson 1 , L. Shi 2 , H. Fang 3 , S. Ali 1 and W. Slikker 1 . 1 2 Neurotoxicology, NCTR, Jefferson, AR, System Toxicology, NCTR, Jefferson, AR and 3 Division of Bioinformatics, Z-Tech Corporation, NCTR, Jefferson, AR. #1099 MICROARRAY ANALYSIS DETECTED GENE EXPRESSION CHANGES IN PC12 CELLS AFTER EXPOSURE TO THE NEUROTOXIN MPP + S. F. Ali 1 , Z. A. Xu 1 , T. Han 2 , T. A. Patterson 1 , L. Shi 2 , H. Fang 3 , D. R. Cawthon 1 and W. Slikker 1 . 1 2 Neurotoxicology, NCTR, Jefferson, AR, Systems Toxicology, NCTR, Jefferson, AR and 3 Division of Bioinformatics, Z-Tech Corporation, NCTR, Jefferson, AR. #1100 COMPARISON OF MEMBRANE POTENTIAL- SENSITIVE FLUORESCENT DYES FOR MEASUREMENT OF TOXIN-INDUCED DEPOLARIZATION IN MURINE NEOCORTICAL NEURONS: CHARACTERIZATION OF BREVETOXIN-AND KCL-INDUCED DEPOLARIZATION. J. H. Peterson and T. F. Murray. Physiology and Pharmacology, University of Georgia, Athens, GA. #1101 BREVENOL, A NATURAL BREVETOXIN ANTAGONIST: COMPETITIVE ANTAGONIST OR ALLOSTERIC MODULATOR? E. P. Gold 1,2 , H. Jacocks 2 , A. J. Bourdelais 2 and D. G. Baden 2,1 . 1 Biological Sciences, UNCW, Wilmington, NC and 2 Center for Marine Science, UNCW, Wilmington, NC. #1102 FEASIBILITY OF CONTINUOUS INTRACEREBRO-VENTRICULAR (ICV) INFUSION IN THE RAT FOR 28 DAYS. K. Tenneson and C. Copeman. Toxicology, CTBR, Senneville, QC, Canada. Sponsor: M. Vezina. #1103 TEMPORAL ANALYSIS OF OPIATE-INDUCED INTRATHECAL GRANULOMATUS MASSES PROGRESSION AND REGRESSION USING MRI. J. W. Allen 1 , K. Horais 1 , N. Tozier 1 , J. Corbeil 2 , R. F. Mattrey 2 and T. L. Yaksh 1 . 1 Anesthesiology, University CA-San Diego, La Jolla, CA and 2 Radiology, University CA-San Diego, La Jolla, CA. #1104 A COMPARATIVE EVALUATION OF ANIMAL CHARACTERISTICS AND DEVELOPMENT OF CHOROIDAL NEOVASCULARIZATION (CNV) IN A LASER-INDUCED NON-HUMAN PRIMATE MODEL OF MACULAR DEGENERATION. M. Wills. Development and Discovery Services, Charles River Laboratories, Sparks, NV. #1105 ALZHEIMER’S DISEASE: THE CYNOMOLGUS MONKEY AS A MODEL IN TOXICOLOGICAL RESEARCH? E. Buse, G. Habermann, S. Friderichs- Gromoll, J. Kaspareit and P. Nowak. Covance Laboratories GmbH, 48163 Muenster, Germany. Sponsor: G. Weinbauer. #1106 EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS (EAE) IN THE FEMALE LEWIS RAT. S. Rowton and S. Grainger. Covance Laboratories Ltd., Harrogate, United Kingdom. Sponsor: D. Everett. #1107 ANALYSIS OF MYELIN LOSS USING SCANNING ELECTRON MICROSCOPY (SEM) UNDER FULLY HYDRATED CONDITIONS: VALIDATION IN A MOUSE MODEL OF EXPERIMENTAL AUTOIMMUNE ENCEPHALITIS. V. Behar 3 , E. Blaugrund 3 , A. Mayk 3 , E. Raymond 3 , N. Russek 2 , M. Horowitz 2 and A. Nyska 1 . 1 Laboratory of Experimental Pathology, NIEHS, Research Triangle Park, NC, 2 QuantomiX, Ltd.,, Ness Ziona, Israel and 3 Research & Development, Teva Pharmaceuticals Ltd.,, Sapir Industrial Zone, Israel. 134 SOT’s 44 th Annual Meeting
44 th Annual Meeting and ToxExpo Program Description Tuesday Afternoon, March 8 1:30 PM to 4:30 PM Exhibit Hall POSTER SESSION: FEMALE REPRODUCTIVE Chairperson(s): Moussa Diawara, University of Southern Colorado, Pueblo, CO and Ulrike Luderer, University of California Irvine, Irvine, CA. Displayed: 1:30 PM–4:30 PM Attended: 1:30 PM–3:00 PM #1108 NEONATAL/PREPUBERTAL EXPOSURE TO BUTYL BENZYL PHTHALATE, BUT NOT BISPHENOL A, CAUSES SUBTLE ALTERATIONS TO THE RAT FEMALE REPRODUCTIVE TRACT. C. A. Lamartiniere and E. Abdalla. Pharmacology and Toxicology, University Alabama at Birmingham, Birmingham, AL. #1109 THE ARYL HYDROCARBON RECEPTOR (AHR) IS REQUIRED FOR NORMAL OVULATION IN THE MOUSE. D. Tomic, C. Greenfeld, J. K. Babus and J. A. Flaws. Epidemiology, University of Maryland School of Medicine, Baltimore, MD. #1110 EFFECTS OF ESTROGEN RECEPTOR MODULATORS ON UTERINE PATHOLOGY AND GENE EXPRESSION. D. T. Gray 1 , J. A. Styles 1 , P. Greaves 2 and I. N. White 1 . 1 Cancer Studies and Molecular Medicine, MRC Molecular Endocrinology Group, Leicester, United Kingdom and 2 MRC Toxicology Unit, University of Leicester, Leicester, United Kingdom. Sponsor: A. Smith. #1111 THE ARYL HYDROCARBON RECEPTOR (AHR) REDUCES EXPRESSION OF ENZYMES IN THE ESTROGEN BIOSYNTHESIS PATHWAY. C. B. Mainor 1 , K. Barnett 2 , D. Tomic 2 and J. Flaws 2 . 1 University of Maryland Baltimore County, Baltimore, MD and 2 University of Maryland School of Medicine, Baltimore, MD. #1112 THE ARYL HYDROCARBON RECEPTOR (AHR) REGULATES OVARIAN FOLLICLE GROWTH IN VITRO. K. Barnett, D. Tomic and J. Flaws. University of Maryland School of Medicine, Baltimore, MD. #1113 ACTIVATION OF TH1 PRO-INFLAMMATORY CYTOKINE EXPRESSION BY ARYL HYDROCARBON RECEPTOR (AHR) LIGANDS IN HUMAN UTERINE ENDOMETRIAL CELLS. K. Shiverick 1 , T. Medrano 1 , N. Chegini 2 and M. James 3 . 1 Department of Pharmacology & Therapeutics, University of Florida, Gainesville, FL, 2 Department of Obstetrics & Gynecology, University of Florida, Gainesville, FL and 3 Department of Medicinal Chemistry, University of Florida, Gainesville, FL. #1114 STIMULATORY AND INHIBITORY EFFECTS OF GENISTEIN ON UTERINE LEIOMYOMA CELL GROWTH IN VITRO IS DETERMINED BY DOSE. L. Castro, A. Moore, L. Yu, C. Bortner, M. Sifre, R. Newbold and D. Dixon. NIEHS, Research Triangle Park, NC. #1115 SUPEROXIDE ANION, HYDROGEN PEROXIDE, AND HYDROXYL RADICALS IN CIGARETTE SMOKE INHIBIT HAMSTER OOCYTE CUMULUS COMPLEX PICKUP. C. Gieseke, R. Pederson and P. Talbot. Cell Biology and Neuroscience, University of California, Riverside, Riverside, CA. Sponsor: B. Krieger. #1116 CHARACTERIZING THE OVOTOXICITY OF CYCLOPHOSPHAMIDE METABOLITES ON CULTURED MOUSE OVARIES IN VITRO. P. J. Devine. Institut Armand-Frappier, Institut national de la recherche scientifique, Pointe Claire, QC, Canada. #1117 EFFECTS OF BUTHIONINE SULFOXIMINE TREATMENT ON THE EXPRESSION OF GLUTAMATE CYSTEINE LIGASE SUBUNITS IN THE RAT OVARY. Y. D. Hoang 1 , A. P. Avakian 2 and U. Luderer 2,1,3 . 1 Community and Environmental Medicine, University of California Irvine, Irvine, CA, 2 Medicine, University of California Irvine, Irvine, CA and 3 Developmental and Cell Biology, University of California Irvine, Irvine, CA. #1118 CUMULATIVE EFFECTS OF THIRAM AND AMITRAZ ON PREGNANCY MAINTENANCE AND DEVELOPMENT IN THE RAT. D. S. Best, M. G. Narotsky and R. L. Cooper. Reproductive Toxicology Division, U.S. EPA, ORD, NHEERL, Research Triangle Park, NC. Sponsor: T. Stoker. #1119 DIBROMOACETIC ACID ATTENTUATES A DITHIOCARBAMATE-INDUCED SUPPRESSION OF THE LH SURGE IN THE RAT. J. M. Goldman, A. S. Murr, A. R. Buckelew, W. McElroy and J. M. Ferrell. Endocrinol. Br., RTD, NHEERL, ORD, U.S. EPA, Res. Triangle Pk., NC. Sponsor: A. Cummings. #1120 A SINGLE DOSE OF 8-METHOXYPSORALEN REDUCES LUTEINIZING HORMONE LEVELS IN FEMALE RATS. M. M. Diawara 1 and P. B. Hoyer 2 . 1 Biology, Colorado State University-Pueblo, Pueblo, CO and 2 Physiology, University of Arizona, Tucson, AZ. #1121 EFFECTS OF FEED RESTRICTION ON FERTILITY AND EARLY EMBRYONIC DEVELOPMENT IN FEMALE RATS. M. S. Gilman, T. L. Fleeman, R. E. Chapin, M. E. Hurtt and K. K. Terry. Pfizer Global Research & Development, Pfizer Inc., Groton, CT. #1122 LATE GESTATIONAL ATRAZINE EXPOSURE ALTERS MATERNAL NURSING BEHAVIOR IN RATS. J. L. Rayner 1 and S. E. Fenton 2 . 1 DESE, UNC- Chapel Hill, Chapel Hill, NC and 2 RTD, NHEERL, ORD, U.S. EPA, Research Triangle Park, NC. #1123 PERIPHERAL BENZODIAZEPINE RECEPTOR LIGAND PK11195 AFFECTS FEMALE FERTILITY AS DEMONSTRATED IN AN IN- VITRO MOUSE FOLLICLE BIOASSAY. E. Gobbers 1 , K. Van Wemmel 1 , J. Smitz 2 and R. Cortvrindt 1,2 . 1 EggCentris NV, Zellik, Belgium and 2 Follicle Biology Laboratory, Vrije Universiteit Brussel, Brussels, Belgium. Sponsor: R. De Coster. TUESDAY up-to-date information at www.toxicology.org 135
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Contents Program Overview .........
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Annual Meeting Events Calendar (Con
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Sheraton Hotel Map 44 th Annual Mee
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Itinerary Planner Computer Stations
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General Information 44 th Annual Me
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2005 Award Winners The Society of T
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2004 Student Award Winners Colgate-
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INTERNATIONAL HARMONIZATION OF TECH
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Saturday Afternoon, March 5 2:00 PM
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SOT Affiliates for 2005 44 th Annua
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Program - Society of Toxicology

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