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44 th Annual Meeting and ToxExpo Program Description MONDAY #431 CATEGORIZATION OF THE ASSOCIATIONS BETWEEN EXPOSURE TO THE HERBICIDES USED IN VIETNAM OR THEIR CONTAMINANTS AND HEALTH OUTCOMES. J. Cohen and M. Catlin. The National Academies, Washington, DC. #432 THE IMPACT OF REDUCTION OF THE OCCUPATIONAL EXPOSURE LIMIT FOR FORMALDEHYDE IN QUEBEC: A RE- EVALUATION OF HEALTH RISKS. N. Noisel, M. Bouchard and G. Carrier. Sante Environnementale & Sante Au Travail, Universite de Montreal, Montreal, QC, Canada. Monday Afternoon, March 7 1:30 PM to 4:30 PM Exhibit Hall POSTER SESSION: RESPIRATORY TRACT I–PULMONARY, CARDIOVASCULAR, AND IMMUNE EFFECTS OF PM CHAIRPERSON(S): PRAMILA SINGH, U.S. EPA, RESEARCH TRIANGLE PARK, NC AND MICHELLE V. FANUCCHI, UC DAVIS, DAVIS, CA. Displayed: 1:30 PM–4:30 PM Attended: 1:30 PM–3:00 PM #433 EFFECTS OF INHALED COMBUSTION- DERIVED PARTICULATE MATTER ON INDICES OF CARDIAC, PULMONARY, AND THERMOREGULATORY FUNCTION IN SPONTANEOUSLY HYPERTENSIVE RATS. L. B. Wichers 1 , W. H. Rowan 2 , J. P. Nolan 2 , U. P. Kodavanti 2 , M. J. Schladweiler 2 , A. D. Ledbetter 2 , D. L. Costa 2 and W. P. Watkinson 2 . 1 SPH, UNC, Chapel Hill, NC and 2 ORD/NHEERL/ETD/PTB, U.S. EPA, Research Triangle Park, NC. #434 CARDIOPULMONARY EFFECT OF PARTICULATE MATTERS ON DIABETIC RATS: FROM CAPS TO ULTRAFINE PARTICLES. Y. Lei and T. Cheng. College of Public Health, National Taiwan University, Taipei, Taiwan. Sponsor: T. Ueng. #435 TOXICOGENOMIC EXPRESSION PROFILES OF SPONTANEOUSLY HYPERTENSIVE RATS EXPOSED TO CONCENTRATED AMBIENT PARTICLES. Y. Lei and T. Cheng. Public Health, National Taiwan University, Taipei, Taiwan. Sponsor: T. Ueng. #436 TIME-COURSE OF INFLAMMATION AND TISSUE DAMAGE IN THE MOUSE LUNG CAUSED BY FINE PARTICULATE MATTER FROM SIX EUROPEAN CITIES (PAMCHAR). M. S. Happo 1,2 , R. O. Salonen 1 , A. I. Halinen 1 , P. Jalava 1,2 and M. Hirvonen 1 . 1 Department of Environmental Health, National Public Health Institute, Kuopio, Finland and 2 University of Kuopio, Kuopio, Finland. Sponsor: M. Viluksela. #437 EXPOSURE TO CONCENTRATED AMBIENT PARTICLES DOES NOT AFFECT ENDOTHELIAL VASOMOTOR FUNCTION IN PATIENTS WITH ISCHEMIC HEART DISEASE. N. L. Mills 1 , D. E. Newby 1 , S. D. Robinson 1 , D. Anderson 1 , E. Freney 1 , D. Robert 1 , N. A. Boon 1 , W. MacNee 1 , K. Donaldson 1 and F. Cassee 2 . 1 Centre for Cardiovascular Science, ELEGI Colt Research Laboratories or Department of Chemistry, University of Edinburgh, Edinburgh, United Kingdom and 2 Centre for Environmental Health Research, National Institute for Public Health and the Environment, Bilthoven, Netherlands. #438 EXPOSURE TO CONCENTRATED AMBIENT PARTICLES IN DETROIT ALTERS HEART RATE VARIABILITY IN SPONTANEOUSLY HYPERTENSIVE RATS. J. G. Wagner 1 , L. B. Wichers 2 , M. Morishita 3 , A. C. Rohr 4 , G. J. Keeler 3 and J. R. Harkema 1 . 1 Michigan State University, East Lansing, MI, 2 U.S. EPA -NHEERL, Research Triangle Park, NC, 3 University Michigan, Ann Arbor, MI and 4 Electrical Power Research Inst, Palo Alto, CA. #439 EXPOSURE TO CONCENTRATED AMBIENT PARTICLES IN DETROIT, MICHIGAN CAUSES HEART RATE AND THERMOREGULATORY CHANGES IN SPONTANEOUSLY HYPERTENSIVE AND WISTAR-KYOTO RATS. A. C. Rohr 1 , J. G. Wagner 2 , M. Morishita 3 , G. J. Keeler 3 and J. R. Harkema 2 . 1 EPRI, Palo Alto, CA, 2 Michigan State University, East Lansing, MI and 3 University of Michigan, Ann Arbor, MI. #440 SUBCHRONIC EFFECTS OF CONCENTRATED AMBIENT PARTICLES (CAPS) IN SENESCENT MICE (AKR). Q. LI and L. Chen. Environmental Health, NYU School of Medicine, Tuxedo, NY. #441 CARDIAC INJURY FROM LONG-TERM EPISODIC EXPOSURE TO PARTICULATE MATTER (PM): SOLUBLE COMPONENTS OR SOLID PARTICLES? U. P. Kodavanti 1 , M. C. Schladweiler 1 , A. D. Ledbetter 1 , J. McGee 1 , P. S. Gilmour 2 , W. P. Watkinson 1 , D. C. Christiani 3 , D. L. Costa 1 , R. H. Jaskot 1 , J. H. Richards 1 and A. Nyska 4 . 1 ETD/NHEERL/ORD, U.S. EPA, Research Triangle Park, NC, 2 CEMALB, UNC, Chapel Hill, NC, 3 HSPH, Boston, MA and 4 NIEHS, Research Triangle Park, NC. #442 HEART RATE CHANGES IN 24-MONTH OLD FISHER 344 RATS EXPOSED TO CONCENTRATED PARTICULATE MATTER (PM2.5) CLOSE TO A FREEWAY IN DIAMOND BAR, CA. A. K. hamade, T. Lam and M. T. Kleinman. University of California, Irvine, CA. Sponsor: H. Hamadeh. #443 EFFECTS OF ON-ROAD AEROSOLS IN AGED RATS. A. Elder 1 , N. Corson 1 , P. Mercer 1 , R. Gelein 1 , J. Finkelstein 2 , P. Hopke 3 , W. Watts 4 , D. Kittelson 4 and G. Oberdorster 1 . 1 Environment Med., University of Rochester, Rochester, NY, 2 Ped., University of Rochester, Rochester, NY, 3 Chem. Eng., Clarkson University, Potsdam, NY and 4 Mech. Eng., University of Minnesota, Minneapolis, MN. 80 SOT’s 44 th Annual Meeting
44 th Annual Meeting and ToxExpo Program Description #444 COLLECTION, AEROSOLIZATION, AND CHARACTERIZATION OF PAVED ROAD DUST FOR AN INHALATION TOXICITY STUDY. J. McDonald, E. Barr and J. L. Mauderly. Toxicology, Lovelace Respiratory Research Institute, Albuquerque, NM. #445 CHEMICAL, MICROBIOLOGICAL AND TOXICOLOGICAL CHARACTERIZATION OF FINE PARTICULATE MATTER (PM2.5) FROM AN INDOOR ENVIRONMENT IN PUERTO RICO. A. Gioda 1 , E. Fuentes-Mattei 2,1 , B. Bolanos 2 and B. D. Jimenez-Velez 2,1 . 1 Center of Environmental and Toxicological Research-UPR Medical Science Campus, San Juan, PR, Puerto Rico and 2 Biochemistry, UPR Medical Science Campus, San Juan, PR, Puerto Rico. #446 HIGH NO2/NOX RATIO IN DIESEL ENGINE EMISSION AEROSOL MAY REPRESENT A MORE IMPORTANT ACUTE TOXIC TRIGGER THAN PARTICULATE MATTER (PM) FOR LUNG TISSUE. J. MORIN 1 , A. Bion 1,2 , V. Keravec 2,1 and F. Dionnet 2 . 1 INSERM U644, Rouen, France and 2 CERTAM, Saint Etienne du Rouvray, France. Sponsor: R. FORSTER. #447 EFFECTS OF DIESEL EXHAUST ON TLR3 SIGNALING IN RESPIRATORY EPITHELIAL CELLS. J. M. Ciencewicki 1 , M. Madden 3,1 and I. Jaspers 2,1 . 1 Curriculum of Toxicology, University of North Carolina, Chapel Hill, NC, 2 Pediatrics, University of North Carolina, Chapel Hill, NC and 3 Human Studies Division, U.S. EPA, Chapel Hill, NC. #448 NEUROTROPHIN RECEPTOR BLOCKADE ATTENUATES DIESEL EXHAUST PARTICULATE MATTER (DEP) ENHANCEMENT OF ALLERGIC RESPONSES. A. K. Farraj 1,2 , N. Haykal-Coates 2 , A. D. Ledbetter 2 , P. A. Evansky 2 and S. H. Gavett 2 . 1 Molecular and Biomedical Sciences, North Carolina State University, Raleigh, NC and 2 Experimental Toxicology Division, NHEERL, ORD, U.S. EPA, Research Triangle Park, NC. #449 YM1/2 CHITINASE PROTEINS IN MURINE NASAL EPITHELIUM AFTER A 13-WEEK INHALATION EXPOSURE TO ULTRAFINE CARBON BLACK PARTICLES. J. R. Harkema 1 , P. Santhanam 1 , J. G. Wagner 1 , L. A. Bramble 1 , A. P. Elder 2 and G. Oberdorster 2 . 1 Pathobiology and Diagnostic Invesitgation, Michigan State University, East Lansing, MI and 2 Environmental Medicine, University of Rochester, Rochester, NY. #450 PARTICLE SURFACE AREA AND PARTICLE NUMBER, BUT NOT PARTICLE MASS, PREDICT THE ADJUVANT EFFECT OF PARTICLES ON ALLERGIC RESPONSES IN MICE. U. C. Nygaard, M. Samuelsen, A. Aase and M. Lovik. Environmental Immunology, Norwegian Institute of Public Health, Oslo, Norway. Sponsor: E. Dybing. #451 CHEMICAL CHARACTERISTICS AND TOXICITY OF POLAR ORGANIC EXTRACT OF DIESEL EXHAUST PARTICLES. T. Kobayashi 1 , H. Shima 1 and E. Koike 2 . 1 Environmental Health Sciences Division, National Institute for Environmental Studies, Tsukuba, Ibaragi, Japan and 2 PM2.5 and DEP Research Project, National Institute for Environmental Studies, Tsukuba, Ibaragi, Japan. Sponsor: S. Hirano. #452 ORGANIC EXTRACT OF DIESEL EXHAUST PARTICLES STIMULATES EXPRESSION OF IA AND COSTIMULATORY MOLECULES ASSOCIATED WITH ANTIGEN PRESENTATION IN RAT PERIPHERAL BLOOD MONOCYTES BUT NOT ALVEOLAR MACROPHAGES. E. KOIKE 1 and T. KOBAYASHI 2 . 1 PM2.5 and DEP Research Project, National Institute for Environmental Studies, Tsukuba, Ibaraki, Japan and 2 Environmental Health Sciences Division, National Institute for Environmental Studies, Tsukuba, Ibaraki, Japan. Sponsor: S. Hirano. #453 WOOD SMOKE PARTICLES INCREASE ALLERGIC RESPONSES IN MICE, BUT LESS THAN DIESEL EXHAUST PARTICLES (DEP). M. Samuelsen, U. C. Nygaard and M. Lovik. Norwegian Institute of Public Health, Oslo, Norway. Sponsor: E. Dybing. #454 COMPARISON OF PULMONARY TOXICITY BETWEEN HEALTHY SPRAGUE-DAWLEY RATS AND SPONTANEOUSLY HYPERTENSIVE RATS EXPOSED TO DIESEL EXHAUST PARTICLES. W. Chang, Y. Lei and T. Cheng. College of Public Health, Institute of Occupational Medicine and Industrial Hygiene, Taipei, Taiwan. Sponsor: T. Ueng. #455 APOE MOUSE MODEL OF ATHEROSCLEROSIS CONFERS SUSCEPTIBILITY TO EXTRAPULMONARY EFFECTS OF DIESEL EXHAUST. M. J. Campen, J. Seagrave, L. Blair, S. Lucas, A. Gigliotti, M. Reed and J. McDonald. Toxicology, Lovelace Respiratory Research Institute, Albuquerque, NM. #456 RELATIVE EFFICACY OF COMBUSTION EMISSION PARTICULATE MATTER TO ADSORB THE NEUTROPHIL-ATTRACTING CHEMOKINE IL-8. J. Seagrave and C. Knall. Lovelace Respiratory Research Institute, Albuquerque, NM. #457 DIESEL EXHAUST PARTICLES SUPPRESS LPS- STIMULATED PRODUCTION OF PGE2 IN HUMAN ALVEOLAR MACROPHAGES: ROLE OF P38 MAPK AND ERK PATHWAYS. M. C. Madden 1 , S. Becker 1 and S. Mundandhara 2 . 1 ORD, NHEERL, HSD, Clinical Research Branch, U.S. EPA, Chapel Hill, NC and 2 CEMALB, University N. Carolina, Chapel Hill, NC. #458 SULFORAPHANE, A POTENT PHASE 2 INDUCER, INHIBITS THE ADJUVANT EFFECT OF AEROSOLIZED DIESEL EXHAUST PARTICLES IN A MURINE MODEL FOR OVALBUMIN SENSITIZATION. M. J. Whitekus, S. A. Ritz and D. Diaz-Sanchez. UCLA School of Medicine/Division of Clinical Immunology and Allergy, UCLA, Los Angeles, CA. MONDAY up-to-date information at www.toxicology.org 81
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Annual Meeting Events Calendar (Con
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Program - Society of Toxicology

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