Sak 03807 O Vedlegg Fagleg Rapportering 2006 - Helse Vest

370show a broad cytokine release profile including high levels of interferon-gamma that can be further increasedby a novel protein kinase C agonist PEP005."Cancer Immunol Immunother. 2006PMID: 17115221Bruserud Ø, Stapnes C, Tronstad KJ, Ryningen A, Anensen N, Gjertsen BT"Protein lysine acetylation in normal and leukaemic haematopoiesis: HDACs aspossible therapeutic targets in adult AML."Expert Opin Ther Targets. 2006;10(1):51-68PMID: 16441228Anensen N, Skavland J, Stapnes C, Ryningen A, Børresen-Dale AL, Gjertsen BT, Bruserud Ø"Acute myelogenous leukemia in a patient with Li-Fraumeni syndrome treated withvalproic acid, theophyllamine and all-trans retinoic acid: a case report."Leukemia. 2006;20(4):734-6PMID: 16437140Van Belle W, Sjøholt G, Anensen N, Høgda KA, Gjertsen BT"Adaptive contrast enhancement of two-dimensional electrophoretic protein gelimages facilitates visualization, orientation and alignment."Electrophoresis. 2006;27(20):4086-95PMID: 16983632Van Belle W, Anensen N, Haaland I, Bruserud Ø, Høgda KA, Gjertsen BT"Correlation analysis of two-dimensional gel electrophoretic protein patternsand biological variables."BMC Bioinformatics. 2006;7:198PMID: 16606449Anensen N, Haaland I, D'Santos C, Van Belle W, Gjertsen BT"Proteomics of p53 in diagnostics and therapy of acute myeloid leukemia."Curr Pharm Biotechnol. 2006;7(3):199-207PMID: 16789904Ryningen A, Ersvaer E, Øyan AM, Kalland KH, Vintermyr OK, Gjertsen BT, Bruserud Ø"Stress-induced in vitro apoptosis of native human acute myelogenous leukemia(AML) cells shows a wide variation between patients and is associated with low BCL-2:Bax ratio and lowlevels of heat shock protein 70 and 90."Leuk Res. 2006;30(12):1531-40PMID: 16600371Øyan AM, Bø TH, Jonassen I, Gjertsen BT, Bruserud Ø, Kalland KH"cDNA microarray analysis of non-selected cases of acute myeloid leukemia demonstratesdistinct clustering independent of cytogenetic aberrations and consistent with morphological signs ofdifferentiation."Int J Oncol. 2006;28(5):1065-80PMID: 16596222Anensen N, Oyan AM, Bourdon JC, Kalland KH, Bruserud O, Gjertsen BT"A distinct p53 protein isoform signature reflects the onset of induction chemotherapyfor acute myeloid leukemia."Clin Cancer Res. 2006;12(13):3985-92PMID: 16818696Stapnes C, Ryningen A, Gjertsen BT, Bruserud Ø"Treatment with valproic acid, all-trans retinoic acid (ATRA) and theophyllaminefor 9 days caused a persistent increase in peripheral blood platelet counts for a patient with acutemyelogenous leukemia."Acta Oncol. 2006;45(3):346-9PMID: 16644583Irish JM, Anensen N, Hovland R, Skavland J, Borresen-Dale AL, Bruserud O, Nolan GP, Gjertsen BT"Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloidleukemia cells with high levels of phosphorylated wild-type p53."Blood. 2006PMID: 171058201 doktorgrader er avlagt i 2006:Ånensen N"p53 protein biosignatures in acute myeloid leukemia"Mars 2006Hovedveileder: Bjørn Tore GjertsenTranslasjonsforskning - Oncogenesis & Cancer Research