Effet chez le porcelet d'une exposition Ã un rÃ©gime co-contaminÃ© en ...

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REFERENCES BIBLIOGRAPHIQUESAABDEL-WAHHAB, M. A., NADA, S. A. & AMRA, H. A. 1999. Effect of aluminosilicates and bentonite onaflatoxin-induced developmental toxicity in rat. Journal of Applied Toxicology, 19, 199-204.ABDEL-WAHHAB, M. A., NADA, S. A. & KHALIL, F. A. 2002. Physiological and toxicological responses inrats fed aflatoxin-contaminated diet with or without sorbent materials. Animal Feed Scienceand Technology, 97, 209-219.ABOU-KARAM, M., ABBAS, H. K. & SHIER, W. T. 2004. N-fatty acylation of hydrolyzed fumonisin B-1,but not of intact fumonisin B-1, strongly enhances in vitro mammalian toxicity. Journal ofToxicology-Toxin Reviews, 23, 123-151.ACCENSI, F., PINTON, P., CALLU, P., ABELLA-BOURGES, N., GUELFI, J. F., GROSJEAN, F. & OSWALD, I. P.2006. Ingestion of low doses of deoxynivalenol does not affect hematological, biochemical,or immune responses of piglets. J Anim Sci, 84, 1935-42.ADAMS, C. A. 2001. Virtues of cleanliness: feed quality and hygiene in total nutrition. FeedingAnimals for Health and Growth. Nottingham UK: Nottingham University Press.ADAMS, C. A. 2004. Food safety and quality: the effect of animal feeds. Nutrition Abstracts andReviews, Series A 74, 41-51.AFSSA, Agence Française de Sécurité Sanitaire des Aliments, 2009. Évaluation des risques liés à laprésence de mycotoxines dans les chaînes alimentaires humaine et animale.AHAMAD, D. B., VAIRAMUTHU, S., BALASUBRAMANIAM, G. A., MANOHAR, B. M. & BALACHANDRAN,C. 2006. Individual and combined effects of citrinin and aflatoxin B1 in broiler chickens: Aclinico-pathology study. Indian Journal of Veterinary Pathology, 30.AL-SADI, R., YE, D. M., DOKLADNY, K. & MA, T. Y. 2008. Mechanism of IL-1 beta-induced increase inintestinal epithelial tight junction permeability. Journal of Immunology, 180, 5653-5661.AL-SADI, R. M. & MA, T. Y. 2007. IL-1 beta causes an increase in intestinal epithelial tight junctionpermeability. Journal of Immunology, 178, 4641-4649.ALLAMEH, A., SAFAMEHR, A., MIRHADI, S. A., SHIVAZAD, M., RAZZAGHI-ABYANEH, M. & AFSHAR-NADERI, A. 2005. Evaluation of biochemical and production parameters of broiler chicks fedammonia treated aflatoxin contaminated maize grains. Animal Feed Science and Technology,122, 289-301.ALMOND, G. W. 1996. Research applications using pigs. Veterinary Clinics of North America-FoodAnimal Practice, 12, 707-&.AMUZIE, C. J., HARKEMA, J. R. & PESTKA, J. J. 2008. Tissue distribution and proinflammatory cytokineinduction by the trichothecene deoxynivalenol in the mouse: Comparison of nasal vs. oralexposure. Toxicology, 248, 39-44.AOUDIA, N., CALLU, P., GROSJEAN, F. & LARONDELLE, Y. 2009. Effectiveness of mycotoxinsequestration activity of micronized wheat fibres on distribution of ochratoxin A in plasma,liver and kidney of piglets fed a naturally contaminated diet. Food and Chemical Toxicology,47, 1485-1489.ARAVIND, K. L., PATIL, V. S., DEVEGOWDA, G., UMAKANTHA, B. & GANPULE, S. P. 2003. Efficacy ofesterified glucomannan to counteract mycotoxicosis in naturally contaminated feed onperformance and serum biochemical and hematological parameters in broilers. PoultryScience, 82, 571-576.AVANTAGGIATO, G., HAVENAAR, R. & VISCONTI, A. 2003. Assessing the zearalenone-binding activityof adsorbent materials during passage through a dynamic in vitro gastrointestinal model.Food and Chemical Toxicology, 41, 1283-1290.AVANTAGGIATO, G., HAVENAAR, R. & VISCONTI, A. 2004. Evaluation of the intestinal absorption ofdeoxynivalenol and nivalenol by an in vitro gastrointestinal model, and the binding efficacy ofactivated carbon and other adsorbent materials. Food and Chemical Toxicology, 42, 817-824.189
REFERENCES BIBLIOGRAPHIQUESAVANTAGGIATO, G., SOLFRIZZO, M. & VISCONTI, A. 2005. Recent advances on the use of adsorbentmaterials for detoxification of Fusarium mycotoxins. Food Additives and Contaminants, 22,379-388.AWAD, W. A., BOHM, J., RAZZAZI-FAZELI, E. & ZENTEK, J. 2006. Effects of feeding deoxynivalenolcontaminated wheat on growth performance, organ weights and histological parameters ofthe intestine of broiler chickens. Journal of Animal Physiology and Animal Nutrition, 90, 32-37.AWAD, W. A., GHAREEB, K., BOHM, J. & ZENTEK, J. 2010. Decontamination and detoxificationstrategies for the Fusarium mycotoxin deoxynivalenol in animal feed and the effectiveness ofmicrobial biodegradation. Food Additives and Contaminants Part a-Chemistry AnalysisControl Exposure & Risk Assessment, 27, 510-520.AYRAL, A. M., DUBECH, N., LEBARS, J. & ESCOULA, L. 1992. Invitro Effect of Diacetoxyscirpenol andDeoxynivalenol on Microbicidal Activity of Murine Peritoneal-Macrophages. Mycopathologia,120, 121-127.AZCONAOLIVERA, J. I., OUYANG, Y., MURTHA, J., CHU, F. S. & PESTKA, J. J. 1995. Induction of CytokineMessenger-Rnas in Mice after Oral-Exposure to the Trichothecene Vomitoxin(Deoxynivalenol) - Relationship to Toxin Distribution and Protein-Synthesis Inhibition.Toxicology and Applied Pharmacology, 133, 109-120.AZIZ, N. H. & YOUSSEF, B. M. 2002. Inactivation of Naturally Occurring of Mycotoxins in someEgyptian Foods and Agricultural Commodities by Gamma-Irradiation. Egyptian Journal ofFood Science, 30, 167-177.BBACON, C. W., PORTER, J. K. & NORRED, W. P. 1995. Toxic Interaction of Fumonisin B-1 and FusaricAcid Measured by Injection into Fertile Chicken Egg. Mycopathologia, 129, 29-35.BATA, A. & LASZTITY, R. 1999. Detoxification of mycotoxin-contaminated food and feed bymicroorganisms. Trends in Food Science & Technology, 10, 223-228.BAUER, J. 1994. Methods for Detoxification of Mycotoxins in Feedstuffs. Monatshefte FurVeterinarmedizin, 49, 175-181.BEAVER, R. W., WILSON, D. M., JAMES, M. A., HAYDON, K. D., COLVIN, B. M., SANGSTER, L. T., PIKUL,A. H. & GROOPMAN, J. D. 1990. Distribution of Aflatoxins in Tissues of Growing-Pigs Fed anAflatoxin-Contaminated Diet Amended with a High-Affinity Aluminosilicate Sorbent.Veterinary and Human Toxicology, 32, 16-18.BENNETT, G. A. & ANDERSON, R. A. 1978. Distribution of Aflatoxin and-or Zearalenone in Wet-MilledCorn Products - Review. Journal of Agricultural and Food Chemistry, 26, 1055-1060.BENNETT, G. A., PEPLINSKI, A. J., BREKKE, O. L., JACKSON, L. K. & WICHSER, W. R. 1976. Zearalenone -Distribution in Dry-Milled Fractions of Contaminated Corn. Cereal Chemistry, 53, 299-307.BENNETT, G. A. & RICHARD, J. L. 1996. Influence of processing on Fusarium mycotoxins incontaminated grains. Food Technology, 50, 235-238.BENNETT, G. A., SHOTWELL, O. L. & HESSELTINE, C. W. 1980. Destruction of Zearalenone inContaminated Corn. Journal of the American Oil Chemists Society, 57, 245-247.BERGSJO, B., LANGSETH, W., NAFSTAD, I., JANSEN, J. H. & LARSEN, H. J. S. 1993. The Effects ofNaturally Deoxynivalenol-Contaminated Oats on the Clinical Condition, Blood Parameters,Performance and Carcass Composition of Growing Pigs. Veterinary ResearchCommunications, 17, 283-294.BERMUDEZ, A. J., LEDOUX, D. R., ROTTINGHAUS, G. E. & BENNETT, G. A. 1997. The individual andcombined. Effects of the fusarium mycotoxins moniliformin and fumonisin B-1 in turkeys.Avian Diseases, 41, 304-311.190
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AUTEUR : Bertrand GRENIERTITRE : Ef
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REMERCIEMENTSLe travail ici présen
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J’ai une pensée particulière po
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Grenier, B., Loureiro-Bracarense, A
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TABLE DES MATIERES ................
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LISTE DES ABREVIATIONSAFAflatoxineD
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FIGURES ET TABLEAUXFigure 1 : Mycot
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INTRODUCTION8
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INTRODUCTIONCONTEXTE DE L’ETUDELe
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INTRODUCTIONElle se présentait sou
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INTRODUCTIONl’utilisation de ce m
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INTRODUCTION1. Les mycotoxines : g
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INTRODUCTIONc) La zéaralénone (vo
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INTRODUCTIONleucoencéphalomalacies
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INTRODUCTIONMycotoxins co-contamina
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INTRODUCTIONINTRODUCTIONFood safety
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INTRODUCTIONCHARACTERIZATION OF THE
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Quail(140 d)AF-FBRabbit(21 d)AF-FBR
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INTRODUCTIONdue to the ingestion of
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Table 2 : Interaction between Aflat
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(49 d) - RW-L ↗- Ab SRBC ↘- RW-
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INTRODUCTIONb) effects AF and OTA o
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INTRODUCTIONThe depletion of lympho
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AF-T2Chicken 0.3 - 3.0(35 d)AF-T2Ra
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INTRODUCTIONonly seen in birds give
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(30 d) 2AF-RUBGuinea pig 0.02 bw -(
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INTRODUCTIONbetween AF and CPA on t
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(21 day) - RBC, hemoglobin ↗- AST
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INTRODUCTIONII. INTERACTIONS BETWEE
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INTRODUCTIONwhereas in the experime
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INTRODUCTION2.2) TCT type A and BTw
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Table 6 : Interaction between Ochra
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T2-CPAChicken(28 d)T2-CPAChicken(21
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INTRODUCTIONexposed group (Brown et
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INTRODUCTION2.3) Interaction betwee
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INTRODUCTIONeffects in comparison t
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INTRODUCTION3. Procédés de décon
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INTRODUCTIONPhysical and chemical m
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INTRODUCTIONINTRODUCTIONConsumption
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INTRODUCTIONmm screen shows that fr
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INTRODUCTIONseparate the grain into
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Table 7 : toxicological evaluation
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INTRODUCTIONextrusion parameters ra
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INTRODUCTION- an important loss of
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INTRODUCTIONal., 2005). The fate of
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INTRODUCTIONby a steeping period. S
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INTRODUCTIONon cell tissue cultures
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INTRODUCTIONCONCLUSIONDetoxificatio
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INTRODUCTIONMycotoxin Reduction in
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INTRODUCTIONINTRODUCTIONMycotoxin-p
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INTRODUCTIONI. ADSORPTION OF MYCOTO
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Rats3000 ppb 0.5 %2500 ppb 0.5 %250
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INTRODUCTIONIn studies of the poten
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INTRODUCTIONSubstances investigated
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Table 9 : Outcome of yeast cell wal
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INTRODUCTIONFurthermore, cholestyra
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INTRODUCTIONwall peptidoglycans and
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INTRODUCTIONII. BIOLOGICAL DETOXIFI
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INTRODUCTIONdecrease in toxin-conce
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INTRODUCTIONCONCLUSIONPrevention an
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TRAVAILEXPERIMENTAL90
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TRAVAIL EXPERIMENTALtoxicité gén
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TRAVAIL EXPERIMENTALRESUME DES ETUD
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These are not the final page number
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TRAVAIL EXPERIMENTALChronic ingesti
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TRAVAIL EXPERIMENTALINTRODUCTIONMyc
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TRAVAIL EXPERIMENTALMATERIAL & METH
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TRAVAIL EXPERIMENTALthrough a grade
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Figure 5ABCDVilli height (µm)5432a
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TRAVAIL EXPERIMENTALRESULTS1) Histo
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Figure 8ILEUM2.01.6TNF-αbbb2.52.0I
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TRAVAIL EXPERIMENTAL3) Intestinal i
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TRAVAIL EXPERIMENTALtreated group t
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TRAVAIL EXPERIMENTALThe potencial e
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TRAVAIL EXPERIMENTALQuantification
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Figure 10 :(a) Réaction de deesté
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TRAVAIL EXPERIMENTALrévélé de l
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TRAVAIL EXPERIMENTALABSTRACTFumonis
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TRAVAIL EXPERIMENTALintestinal leve
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TRAVAIL EXPERIMENTAL3) Experimental
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TRAVAIL EXPERIMENTALthe importance
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Figure 11 : Effects of FB1 and HFB1
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Table 15 : Effects of FB1 and HFB1
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Table 17 : Effects of FB1 and HFB1
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TRAVAIL EXPERIMENTALDISCUSSIONThe a
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TRAVAIL EXPERIMENTALassociated lymp
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TRAVAIL EXPERIMENTALHartinger et al
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Figure 13 :(a) Transformation par v
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Figure 14 :Illustrations de la proc
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Figure 15 :Plan expérimental de la
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TRAVAIL EXPERIMENTAL4) Analyses du
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TRAVAIL EXPERIMENTAL9) Analyses sta
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TRAVAIL EXPERIMENTALRESULTATS1) Eff
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TRAVAIL EXPERIMENTAL2) Effet des ag
Page 200 and 201: TRAVAIL EXPERIMENTALb,cca,ba,b,da,d
Page 202 and 203: TRAVAIL EXPERIMENTALL’exposition
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Page 208 and 209: TRAVAIL EXPERIMENTALDISCUSSIONLes o
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Page 212 and 213: DISCUSSIONGENERALE160
Page 214 and 215: DISCUSSION GENERALEDans ce travail
Page 216 and 217: DISCUSSION GENERALEdes vaches laiti
Page 218 and 219: Tableau 24 : Analyse de denrées ag
Page 220 and 221: DISCUSSION GENERALEet al., 2008b).
Page 222 and 223: DISCUSSION GENERALE• une réactio
Page 224 and 225: DISCUSSION GENERALE2. Les systèmes
Page 226 and 227: DISCUSSION GENERALEMycoplasma agala
Page 228 and 229: DISCUSSION GENERALEoptimale. Les au
Page 230 and 231: DISCUSSION GENERALEsphingomyéline
Page 232 and 233: DISCUSSION GENERALEsignalisation ce
Page 234 and 235: DISCUSSION GENERALEL’IMMUNITÉ IN
Page 236 and 237: DISCUSSION GENERALEplus spécifique
Page 238 and 239: DISCUSSION GENERALEsouligner que le
Page 240 and 241: DISCUSSION GENERALELA CARBOXYLESTER
Page 242 and 243: DISCUSSION GENERALEde HFB1. Toutefo
Page 244 and 245: CONCLUSIONS184
Page 246 and 247: CONCLUSIONSLes effets d’expositio
Page 248 and 249: CONCLUSIONSest utilisée lorsque la
Page 252 and 253: REFERENCES BIBLIOGRAPHIQUESBHANDARI
Page 254 and 255: REFERENCES BIBLIOGRAPHIQUESCASADO,
Page 256 and 257: REFERENCES BIBLIOGRAPHIQUESDEGIRMEN
Page 258 and 259: REFERENCES BIBLIOGRAPHIQUESETIENNE,
Page 260 and 261: REFERENCES BIBLIOGRAPHIQUESGRENIER,
Page 262 and 263: REFERENCES BIBLIOGRAPHIQUESHERZALLA
Page 264 and 265: REFERENCES BIBLIOGRAPHIQUESKERKADI,
Page 266 and 267: REFERENCES BIBLIOGRAPHIQUESKUMAR, M
Page 268 and 269: REFERENCES BIBLIOGRAPHIQUESMARZOCCO
Page 270 and 271: REFERENCES BIBLIOGRAPHIQUESODHAV, B
Page 272 and 273: REFERENCES BIBLIOGRAPHIQUESPFOHL-LE
Page 274 and 275: REFERENCES BIBLIOGRAPHIQUESREFAI, M
Page 276 and 277: REFERENCES BIBLIOGRAPHIQUESSCHWARTZ
Page 278 and 279: REFERENCES BIBLIOGRAPHIQUESSWANSON,
Page 280 and 281: REFERENCES BIBLIOGRAPHIQUESVEKIRU,
Page 282 and 283: REFERENCES BIBLIOGRAPHIQUESYAN, D.,
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