Effet chez le porcelet d'une exposition Ã un rÃ©gime co-contaminÃ© en ...

More documents

Recommendations

Info

Table 2 : Interaction between Aflatoxins (AF) and Ochratoxin A (OTA)MycotoxinsSpecies(exposure)Doses0.025 –AF-OTA 1.15Chicken egg (µg/egg)(10 d) 1 0.05 – 2.3(µg/egg)AF-OTA 0.025 – 1.0(µg/egg)Chicken egg(15 d) 1 0.05 – 2.0(µg/egg)AF-OTAPig(28 d)AF-OTAChicken(21 d)AF-OTAChicken(42 d)AF-OTAChicken(42 d)AF-OTAChicken(21 d)AF-OTAChicken(42 d)AF-OTACalve(87 d)2.0 – 2.02.5 – 2.02.5 – 2.02.5 – 2.03.5 – 2.00.2 – 0.20.013 –0.450SYNERGISTIC INTERACTIONANTAGONISTIC INTERACTIONLESS THANADDITIVEADDITIVEType 1 Type 2 Type 3 INTERACTIONType 1 Type 2INTERACTION- embryos mortality ↗ - abnormalities ↗- abnormalities ↗ - embryos mortality ↗- abnormalities ↗ - embryos mortality ↗- abnormalities ↗ - embryos mortality ↗- triglycerides ↗ (P) - TP ↗- RW-L ↗- BW ↘- mortality ↗- RW-L,K,G,S,Pv,Pc ↗- BW ↘- prothrombin times ↗- live, dressed,eviscerated weight ↘- carcasse yield, breast,drum, thigh, wing, backweights ↘- plasma carotenoids ↘- BW ↘- ALP ↗- inorganic phosphorus↘- incidence andseverity of breastbruises ↗- BW ↘- RW-L,K,H,Pv ↗- RW-S ↘- DTH reaction ↘- BUN, cholesterol,glucose ↘- calcium →- sodium ↘- incidence and severityof right thigh bruises ↗- albumin →- hemoglobin →- RW-K →- liver lipid levels →- breast yield ↘ - liver lipid levels ↗- hemoglobin ↘- albumin, cholesterol,triglycerides ↘- creatinine, uric acid ↗- ALP ↗- RW-L ↗- RW- BF,T ↘- albumin, TP,cholesterol ↘- Ab ND ↘- WBC ↘- uric acid ↗- AST ↘REFEdringtonet al., 1995Edringtonet al., 1995Harvey etal., 1989aHuff andDoerr, 1981Huff et al.,1983Huff et al.,1984Huff et al.,1992Kalorey etal., 2005Patterson etal., 1981
AF-OTAChicken(35 d)AF-OTAChicken(35 d)AF-OTAGuinea pig(28 d)AF-OTAChicken(42 d)AF-OTAPig(42 d)AF-OTALaying hen(50 d)AF-OTALaying hen(50-75 d)AF-OTAChicken0.3 – 2.00.3 – 2.00.01 mg/d –0.45 mg/d0.2 – 0.20.375 – 1.00.5 – 1.01.0 – 2.02.0 – 4.00.5 – 1.01.0 – 2.02.0 – 4.0- feed consumed forproduction of 1 dozeneggs ↗- metabolizable energy,protein retention ↘- maintenance energyrequirement ↗- maintenance energyrequirement ↗- RW-G,A ↗- GGT ↗- hemoglobin ↘- BW ↘- cholesterol ↘- RW-S,T ↘- Ab ND, DTHreaction ↘- BW, feed intake ↘- ALT ↘- TP, globulin ↘- complement titer ↘- triglyceride ↘- creatinine, uric acid ↗- mortality ↗- RW-L, K ↗- TP, cholesterol, BUN↘-coagulation time →- RW-BF,T ↘- Ab ND, IBD ↘- hemoglobin ↘- RW-L ↗, RW-BF ↘- WBC →Raju andDevegowda, 2000Raju andDevegowda, 2002Richard etal., 1975Sakhare etal., 2007- BWG ↘ - creatinine ↗ - BUN → Tapia andSeawright,1985- egg production ↘ - egg shape index ↘ - feed intake ↘- egg shell thickness →- egg production ↘- feed consumed forproduction of 1 dozeneggs ↗- egg shape index ↘- egg production ↘- feed consumed forproduction of 1 dozeneggs ↗- egg energydeposition ↘- metabolizableenergy, proteinretention, egg energydeposition ↘- metabolizableenergy, proteinretention ↘- feed intake ↘- egg shape index ↘- egg energy deposition↘- maintenance energyrequirement ↗- feed intake ↘ - egg shell thickness↘- egg shell thickness →- BWG ↘- RW-L ↗- Ab SRBC ↘0.5 – 1.0- feed intake ↘- DTH reaction ↘1.0 – 2.0 - feed intake ↘ - BWG ↘ - RW-BF ↘ - RW-K ↗Verma etal., 2003Verma etal., 2007Verma etal., 2004
Page 2 and 3: AUTEUR : Bertrand GRENIERTITRE : Ef
Page 4 and 5: REMERCIEMENTSLe travail ici présen
Page 6 and 7: J’ai une pensée particulière po
Page 8 and 9: Grenier, B., Loureiro-Bracarense, A
Page 10 and 11: TABLE DES MATIERES ................
Page 12 and 13: LISTE DES ABREVIATIONSAFAflatoxineD
Page 14 and 15: FIGURES ET TABLEAUXFigure 1 : Mycot
Page 16 and 17: INTRODUCTION8
Page 18 and 19: INTRODUCTIONCONTEXTE DE L’ETUDELe
Page 20 and 21: INTRODUCTIONElle se présentait sou
Page 22 and 23: INTRODUCTIONl’utilisation de ce m
Page 24 and 25: INTRODUCTION1. Les mycotoxines : g
Page 26 and 27: INTRODUCTIONc) La zéaralénone (vo
Page 28 and 29: INTRODUCTIONleucoencéphalomalacies
Page 30 and 31: INTRODUCTIONMycotoxins co-contamina
Page 32 and 33: INTRODUCTIONINTRODUCTIONFood safety
Page 34 and 35: INTRODUCTIONCHARACTERIZATION OF THE
Page 36 and 37: Quail(140 d)AF-FBRabbit(21 d)AF-FBR
Page 38 and 39: INTRODUCTIONdue to the ingestion of
Page 42 and 43: (49 d) - RW-L ↗- Ab SRBC ↘- RW-
Page 44 and 45: INTRODUCTIONb) effects AF and OTA o
Page 46 and 47: INTRODUCTIONThe depletion of lympho
Page 48 and 49: AF-T2Chicken 0.3 - 3.0(35 d)AF-T2Ra
Page 50 and 51: INTRODUCTIONonly seen in birds give
Page 52 and 53: (30 d) 2AF-RUBGuinea pig 0.02 bw -(
Page 54 and 55: INTRODUCTIONbetween AF and CPA on t
Page 56 and 57: (21 day) - RBC, hemoglobin ↗- AST
Page 58 and 59: INTRODUCTIONII. INTERACTIONS BETWEE
Page 60 and 61: INTRODUCTIONwhereas in the experime
Page 62 and 63: INTRODUCTION2.2) TCT type A and BTw
Page 64 and 65: Table 6 : Interaction between Ochra
Page 66 and 67: T2-CPAChicken(28 d)T2-CPAChicken(21
Page 68 and 69: INTRODUCTIONexposed group (Brown et
Page 70 and 71: INTRODUCTION2.3) Interaction betwee
Page 72 and 73: INTRODUCTIONeffects in comparison t
Page 74 and 75: INTRODUCTION3. Procédés de décon
Page 76 and 77: INTRODUCTIONPhysical and chemical m
Page 78 and 79: INTRODUCTIONINTRODUCTIONConsumption
Page 80 and 81: INTRODUCTIONmm screen shows that fr
Page 82 and 83: INTRODUCTIONseparate the grain into
Page 84 and 85: Table 7 : toxicological evaluation
Page 86 and 87: INTRODUCTIONextrusion parameters ra
Page 88 and 89: INTRODUCTION- an important loss of
Page 90 and 91:
INTRODUCTIONal., 2005). The fate of
Page 92 and 93:
INTRODUCTIONby a steeping period. S
Page 94 and 95:
INTRODUCTIONon cell tissue cultures
Page 96 and 97:
INTRODUCTIONCONCLUSIONDetoxificatio
Page 98 and 99:
INTRODUCTIONMycotoxin Reduction in
Page 100 and 101:
INTRODUCTIONINTRODUCTIONMycotoxin-p
Page 102 and 103:
INTRODUCTIONI. ADSORPTION OF MYCOTO
Page 104 and 105:
Rats3000 ppb 0.5 %2500 ppb 0.5 %250
Page 106 and 107:
INTRODUCTIONIn studies of the poten
Page 108 and 109:
INTRODUCTIONSubstances investigated
Page 110 and 111:
Table 9 : Outcome of yeast cell wal
Page 112 and 113:
INTRODUCTIONFurthermore, cholestyra
Page 114 and 115:
INTRODUCTIONwall peptidoglycans and
Page 116 and 117:
INTRODUCTIONII. BIOLOGICAL DETOXIFI
Page 118 and 119:
INTRODUCTIONdecrease in toxin-conce
Page 120 and 121:
INTRODUCTIONCONCLUSIONPrevention an
Page 122 and 123:
TRAVAILEXPERIMENTAL90
Page 124 and 125:
TRAVAIL EXPERIMENTALtoxicité gén
Page 126 and 127:
TRAVAIL EXPERIMENTALRESUME DES ETUD
Page 128 and 129:
These are not the final page number
Page 130 and 131:
Page 132 and 133:
Page 134 and 135:
Page 136 and 137:
Page 138 and 139:
Page 140 and 141:
TRAVAIL EXPERIMENTALChronic ingesti
Page 142 and 143:
TRAVAIL EXPERIMENTALINTRODUCTIONMyc
Page 144 and 145:
TRAVAIL EXPERIMENTALMATERIAL & METH
Page 146 and 147:
TRAVAIL EXPERIMENTALthrough a grade
Page 148 and 149:
Figure 5ABCDVilli height (µm)5432a
Page 150 and 151:
TRAVAIL EXPERIMENTALRESULTS1) Histo
Page 152 and 153:
Figure 8ILEUM2.01.6TNF-αbbb2.52.0I
Page 154 and 155:
TRAVAIL EXPERIMENTAL3) Intestinal i
Page 156 and 157:
TRAVAIL EXPERIMENTALtreated group t
Page 158 and 159:
TRAVAIL EXPERIMENTALThe potencial e
Page 160 and 161:
TRAVAIL EXPERIMENTALQuantification
Page 162 and 163:
Figure 10 :(a) Réaction de deesté
Page 164 and 165:
TRAVAIL EXPERIMENTALrévélé de l
Page 166 and 167:
TRAVAIL EXPERIMENTALABSTRACTFumonis
Page 168 and 169:
TRAVAIL EXPERIMENTALintestinal leve
Page 170 and 171:
TRAVAIL EXPERIMENTAL3) Experimental
Page 172 and 173:
TRAVAIL EXPERIMENTALthe importance
Page 174 and 175:
Figure 11 : Effects of FB1 and HFB1
Page 176 and 177:
Table 15 : Effects of FB1 and HFB1
Page 178 and 179:
Table 17 : Effects of FB1 and HFB1
Page 180 and 181:
TRAVAIL EXPERIMENTALDISCUSSIONThe a
Page 182 and 183:
TRAVAIL EXPERIMENTALassociated lymp
Page 184 and 185:
TRAVAIL EXPERIMENTALHartinger et al
Page 186 and 187:
Figure 13 :(a) Transformation par v
Page 188 and 189:
Figure 14 :Illustrations de la proc
Page 190 and 191:
Figure 15 :Plan expérimental de la
Page 192 and 193:
TRAVAIL EXPERIMENTAL4) Analyses du
Page 194 and 195:
TRAVAIL EXPERIMENTAL9) Analyses sta
Page 196 and 197:
TRAVAIL EXPERIMENTALRESULTATS1) Eff
Page 198 and 199:
TRAVAIL EXPERIMENTAL2) Effet des ag
Page 200 and 201:
TRAVAIL EXPERIMENTALb,cca,ba,b,da,d
Page 202 and 203:
TRAVAIL EXPERIMENTALL’exposition
Page 204 and 205:
Figure 21 : Effet de l’exposition
Page 206 and 207:
1,41,21,00,80,60,40,20,0IL‐8a,cc
Page 208 and 209:
TRAVAIL EXPERIMENTALDISCUSSIONLes o
Page 210 and 211:
TRAVAIL EXPERIMENTALœdèmes pulmon
Page 212 and 213:
DISCUSSIONGENERALE160
Page 214 and 215:
DISCUSSION GENERALEDans ce travail
Page 216 and 217:
DISCUSSION GENERALEdes vaches laiti
Page 218 and 219:
Tableau 24 : Analyse de denrées ag
Page 220 and 221:
DISCUSSION GENERALEet al., 2008b).
Page 222 and 223:
DISCUSSION GENERALE• une réactio
Page 224 and 225:
DISCUSSION GENERALE2. Les systèmes
Page 226 and 227:
DISCUSSION GENERALEMycoplasma agala
Page 228 and 229:
DISCUSSION GENERALEoptimale. Les au
Page 230 and 231:
DISCUSSION GENERALEsphingomyéline
Page 232 and 233:
DISCUSSION GENERALEsignalisation ce
Page 234 and 235:
DISCUSSION GENERALEL’IMMUNITÉ IN
Page 236 and 237:
DISCUSSION GENERALEplus spécifique
Page 238 and 239:
DISCUSSION GENERALEsouligner que le
Page 240 and 241:
DISCUSSION GENERALELA CARBOXYLESTER
Page 242 and 243:
DISCUSSION GENERALEde HFB1. Toutefo
Page 244 and 245:
CONCLUSIONS184
Page 246 and 247:
CONCLUSIONSLes effets d’expositio
Page 248 and 249:
CONCLUSIONSest utilisée lorsque la
Page 250 and 251:
REFERENCES BIBLIOGRAPHIQUESAABDEL-W
Page 252 and 253:
REFERENCES BIBLIOGRAPHIQUESBHANDARI
Page 254 and 255:
REFERENCES BIBLIOGRAPHIQUESCASADO,
Page 256 and 257:
REFERENCES BIBLIOGRAPHIQUESDEGIRMEN
Page 258 and 259:
REFERENCES BIBLIOGRAPHIQUESETIENNE,
Page 260 and 261:
REFERENCES BIBLIOGRAPHIQUESGRENIER,
Page 262 and 263:
REFERENCES BIBLIOGRAPHIQUESHERZALLA
Page 264 and 265:
REFERENCES BIBLIOGRAPHIQUESKERKADI,
Page 266 and 267:
REFERENCES BIBLIOGRAPHIQUESKUMAR, M
Page 268 and 269:
REFERENCES BIBLIOGRAPHIQUESMARZOCCO
Page 270 and 271:
REFERENCES BIBLIOGRAPHIQUESODHAV, B
Page 272 and 273:
REFERENCES BIBLIOGRAPHIQUESPFOHL-LE
Page 274 and 275:
REFERENCES BIBLIOGRAPHIQUESREFAI, M
Page 276 and 277:
REFERENCES BIBLIOGRAPHIQUESSCHWARTZ
Page 278 and 279:
REFERENCES BIBLIOGRAPHIQUESSWANSON,
Page 280 and 281:
REFERENCES BIBLIOGRAPHIQUESVEKIRU,
Page 282 and 283:
REFERENCES BIBLIOGRAPHIQUESYAN, D.,
show all

Effet chez le porcelet d'une exposition Ã un rÃ©gime co-contaminÃ© en ...

Create successful ePaper yourself

Delete template?

Save as template?