Effet chez le porcelet d'une exposition Ã un rÃ©gime co-contaminÃ© en ...

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REFERENCES BIBLIOGRAPHIQUESGRENIER, B., LOUREIRO-BRACARENSE, A. P., LUCIOLI, J., PACHECO, G., COSSALTER, A. M., MOLL, W.D., SCHATZMAYR, G. & OSWALD, I. P. 2011. Individual and combined effects of subclinicaldoses of deoxynivalenol and fumonisins in piglets. Molecular Nutrition & Food Research, inpress. DOI 10.1002/mnfr.201000402.GUARISCO, J. A., HALL, J. O. & COULOMBE, R. A. 2008. Butylated hydroxytoluene chemoprevention ofaflatoxicosis - Effects on aflatoxin B-1 bioavailability, hepatic DNA adduct formation, andbiliary excretion. Food and Chemical Toxicology, 46, 3727-3731.GUERRE, P. 2000. Interest of the treatments of raw materials and usage of adsorbents todecontaminate animal food containing mycotoxins. Revue De Medecine Veterinaire, 151,1095-1106.GUILLOTEAU, P., ZABIELSKI, R., HAMMON, H. M. & METGES, C. C. 2010. Nutritional programming ofgastrointestinal tract development. Is the pig a good model for man? Nutrition ResearchReviews, 23, 4-22.GUPTA, G. & GARDNER, W. 2005. Use of clay mineral (montmorillonite) for reducing poultry litterleachate toxicity (EC50). Journal of Hazardous Materials, 118, 81-83.GWIAZDOWSKA, D., FILIPIAK, M., CZACZYK, K. & GWIAZDOWSKI, R. 2006. Removal of zearalenonefrom medium by different species of propionibacterium, lactobacillus and bifidobacterium.HHALABI, K. S., NATOUR, R. M. & TAMIMI, S. O. 1998. Individual and combined effects of chronicochratoxin a and zearalenone mycotoxins on rat liver and kidney. Arab Gulf Journal ofScientific Research, 16, 379-392.HALLOY, D. J., GUSTIN, P. G., BOUHET, S. & OSWALD, I. P. 2005. Oral exposure to culture materialextract containing fumonisins predisposes swine to the development of pneumonitis causedby Pasteurella multocida. Toxicology, 213, 34-44.HAMEED, H. G. 1993. Extrusion and Chemical Treatments for Destruction of Aflatoxin in Naturally-Contaminated Corn. University of Arizona.HAN, X. N., FINK, M. P. & DELUDE, R. L. 2003. Proinflammatory cytokines cause no center dotdependentand -independent changes in expression and localization of tight junctionproteins in intestinal epithelial cells. Shock, 19, 229-237.HANIF, N. Q., MUHAMMAD, G., SIDDIQUE, M., KHANUM, A., AHMED, T., GADAHAI, J. A. & KAUKAB,G. 2008. Clinico-pathomorphological, serum biochemical and histological studies in broilersfed ochratoxin A and a toxin deactivator (Mycofix (R) Plus). British Poultry Science, 49, 632-642.HARTINGER, D., HEINL, S., SCHWARTZ, H. E., GRABHERR, R., SCHATZMAYR, G., HALTRICH, D. & MOLL,W. D. 2010. Enhancement of solubility in Escherichia coli and purification of anaminotransferase from Sphingopyxis sp MTA144 for deamination of hydrolyzed fumonisin B-1. Microbial Cell Factories, 9.HARVEY, R. B., EDRINGTON, T. S., KUBENA, L. F., ELISSALDE, M. H., CASPER, H. H., ROTTINGHAUS, G.E. & TURK, J. R. 1996. Effects of dietary fumonisin B-1-containing culture material,deoxynivalenol-contaminated wheat, or their combination on growing barrows. AmericanJournal of Veterinary Research, 57, 1790-1794.HARVEY, R. B., EDRINGTON, T. S., KUBENA, L. F., ELISSALDE, M. H., CORRIER, D. E. & ROTTINGHAUS,G. E. 1995a. Effect of Aflatoxin and Diacetoxyscirpenol in Ewe Lambs. Bulletin ofEnvironmental Contamination and Toxicology, 54, 325-330.HARVEY, R. B., EDRINGTON, T. S., KUBENA, L. F., ELISSALDE, M. H. & ROTTINGHAUS, G. E. 1995b.Influence of Aflatoxin and Fumonisin B-1-Containing Culture Material on Growing Barrows.American Journal of Veterinary Research, 56, 1668-1672.199
REFERENCES BIBLIOGRAPHIQUESHARVEY, R. B., EDRINGTON, T. S., KUBENA, L. F., ROTTINGHAUS, G. E., TURK, J. R., GENOVESE, K. J.,ZIPRIN, R. L. & NISBET, D. J. 2002. Toxicity of fumonisin from Fusarium verticillioides culturematerial and moniliformin from Fusarium fujikuroi culture material when fed singly and incombination to growing barrows. Journal of Food Protection, 65, 373-377.HARVEY, R. B., HUFF, W. E., KUBENA, L. F. & PHILLIPS, T. D. 1989a. Evaluation of DietsCocontaminated with Aflatoxin and Ochratoxin Fed to Growing-Pigs. American Journal ofVeterinary Research, 50, 1400-1405.HARVEY, R. B., KUBENA, L. F., ELISSALDE, M. H., CORRIER, D. E., HUFF, W. E., ROTTINGHAUS, G. E. &CLEMENT, B. A. 1991a. Cocontamination of swine diets by aflatoxin and diacetoxyscirpenol. JVet Diagn Invest, 3, 155-160.HARVEY, R. B., KUBENA, L. F., ELISSALDE, M. H., CORRIER, D. E. & PHILLIPS, T. D. 1994a. Comparisonof 2 Hydrated Sodium-Calcium Aluminosilicate Compounds to Experimentally ProtectGrowing Barrows from Aflatoxicosis. Journal of Veterinary Diagnostic Investigation, 6, 88-92.HARVEY, R. B., KUBENA, L. F., ELISSALDE, M. H. & PHILLIPS, T. D. 1993. Efficacy of Zeolitic OreCompounds on the Toxicity of Aflatoxin to Growing Broiler-Chickens. Avian Diseases, 37, 67-73.HARVEY, R. B., KUBENA, L. F., ELISSALDE, M. H., ROTTINGHAUS, G. E. & CORRIER, D. E. 1994b.Administration of Ochratoxin-a and Ochratoxin-T-2 Toxin to Growing Swine. AmericanJournal of Veterinary Research, 55, 1757-1761.HARVEY, R. B., KUBENA, L. F., HUFF, W. E., CORRIER, D. E., CLARK, D. E. & PHILLIPS, T. D. 1989b.Effects of Aflatoxin, Deoxynivalenol, and Their Combinations in the Diets of Growing-Pigs.American Journal of Veterinary Research, 50, 602-607.HARVEY, R. B., KUBENA, L. F., HUFF, W. E., CORRIER, D. E., ROTTINGHAUS, G. E. & PHILLIPS, T. D.1990. Effects of Treatment of Growing Swine with Aflatoxin and T-2 Toxin. American Journalof Veterinary Research, 51, 1688-1693.HARVEY, R. B., KUBENA, L. F., PHILLIPS, T. D., CORRIER, D. E., ELISSALDE, M. H. & HUFF, W. E. 1991b.Diminution of Aflatoxin Toxicity to Growing Lambs by Dietary Supplementation withHydrated Sodium Calcium Aluminosilicate. American Journal of Veterinary Research, 52, 152-156.HARVEY, R. B., KUBENA, L. F., ROTTINGHAUS, G. E., TURK, J. R., CASPER, H. H. & BUCKLEY, S. A. 1997.Moniliformin from Fusarium fujikuroi culture material and deoxynivalenol from naturallycontaminated wheat incorporated into diets of broiler chicks. Avian Diseases, 41, 957-963.HASCHEK, W. M., GUMPRECHT, L. A., SMITH, G., TUMBLESON, M. E. & CONSTABLE, P. D. 2001.Fumonisin toxicosis in swine: An overview of porcine pulmonary edema and currentperspectives. Environmental Health Perspectives, 109, 251-257.HASKARD, C. A., EL-NEZAMI, H. S., KANKAANPAA, P. E., SALMINEN, S. & AHOKAS, J. T. 2001. Surfacebinding of aflatoxin B-1 by lactic acid bacteria. Applied and Environmental Microbiology, 67,3086-3091.HAYES, A. W., CAIN, J. A. & MOORE, B. G. 1977. Effect of Aflatoxin-B1, Ochratoxin-a and Rubratoxin-Bon Infant Rats. Food and Cosmetics Toxicology, 15, 23-27.HE, P., YOUNG, L. G. & FORSBERG, C. 1992. Microbial Transformation of Deoxynivalenol (Vomitoxin).Applied and Environmental Microbiology, 58, 3857-3863.HEINL, S., HARTINGER, D., THAMHESL, M., VEKIRU, E., KRSKA, R., SCHATZMAYR, G., MOLL, W. D. &GRABHERR, R. 2010. Degradation of fumonisin B-1 by the consecutive action of two bacterialenzymes. Journal of Biotechnology, 145, 120-129.HENDRICH, S., MILLER, K. A., WILSON, T. M. & MURPHY, P. A. 1993. Toxicity of Fusarium-Proliferatum-Fermented Nixtamalized Corn-Based Diets Fed to Rats - Effect of Nutritional-Status. Journal of Agricultural and Food Chemistry, 41, 1649-1654.HERSHBERG, R. M. & MAYER, L. F. 2000. Antigen processing and presentation by intestinal epithelialcells - polarity and complexity. Immunology Today, 21, 123-128.200
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AUTEUR : Bertrand GRENIERTITRE : Ef
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REMERCIEMENTSLe travail ici présen
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J’ai une pensée particulière po
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Grenier, B., Loureiro-Bracarense, A
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TABLE DES MATIERES ................
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LISTE DES ABREVIATIONSAFAflatoxineD
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FIGURES ET TABLEAUXFigure 1 : Mycot
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INTRODUCTION8
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INTRODUCTIONCONTEXTE DE L’ETUDELe
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INTRODUCTIONElle se présentait sou
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INTRODUCTIONl’utilisation de ce m
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INTRODUCTION1. Les mycotoxines : g
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INTRODUCTIONc) La zéaralénone (vo
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INTRODUCTIONleucoencéphalomalacies
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INTRODUCTIONMycotoxins co-contamina
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INTRODUCTIONINTRODUCTIONFood safety
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INTRODUCTIONCHARACTERIZATION OF THE
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Quail(140 d)AF-FBRabbit(21 d)AF-FBR
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INTRODUCTIONdue to the ingestion of
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Table 2 : Interaction between Aflat
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(49 d) - RW-L ↗- Ab SRBC ↘- RW-
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INTRODUCTIONb) effects AF and OTA o
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INTRODUCTIONThe depletion of lympho
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AF-T2Chicken 0.3 - 3.0(35 d)AF-T2Ra
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INTRODUCTIONonly seen in birds give
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(30 d) 2AF-RUBGuinea pig 0.02 bw -(
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INTRODUCTIONbetween AF and CPA on t
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(21 day) - RBC, hemoglobin ↗- AST
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INTRODUCTIONII. INTERACTIONS BETWEE
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INTRODUCTIONwhereas in the experime
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INTRODUCTION2.2) TCT type A and BTw
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Table 6 : Interaction between Ochra
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T2-CPAChicken(28 d)T2-CPAChicken(21
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INTRODUCTIONexposed group (Brown et
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INTRODUCTION2.3) Interaction betwee
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INTRODUCTIONeffects in comparison t
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INTRODUCTION3. Procédés de décon
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INTRODUCTIONPhysical and chemical m
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INTRODUCTIONINTRODUCTIONConsumption
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INTRODUCTIONmm screen shows that fr
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INTRODUCTIONseparate the grain into
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Table 7 : toxicological evaluation
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INTRODUCTIONextrusion parameters ra
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INTRODUCTION- an important loss of
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INTRODUCTIONal., 2005). The fate of
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INTRODUCTIONby a steeping period. S
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INTRODUCTIONon cell tissue cultures
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INTRODUCTIONCONCLUSIONDetoxificatio
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INTRODUCTIONMycotoxin Reduction in
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INTRODUCTIONINTRODUCTIONMycotoxin-p
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INTRODUCTIONI. ADSORPTION OF MYCOTO
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Rats3000 ppb 0.5 %2500 ppb 0.5 %250
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INTRODUCTIONIn studies of the poten
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INTRODUCTIONSubstances investigated
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Table 9 : Outcome of yeast cell wal
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INTRODUCTIONFurthermore, cholestyra
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INTRODUCTIONwall peptidoglycans and
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INTRODUCTIONII. BIOLOGICAL DETOXIFI
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INTRODUCTIONdecrease in toxin-conce
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INTRODUCTIONCONCLUSIONPrevention an
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TRAVAILEXPERIMENTAL90
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TRAVAIL EXPERIMENTALtoxicité gén
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TRAVAIL EXPERIMENTALRESUME DES ETUD
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These are not the final page number
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TRAVAIL EXPERIMENTALChronic ingesti
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TRAVAIL EXPERIMENTALINTRODUCTIONMyc
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TRAVAIL EXPERIMENTALMATERIAL & METH
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TRAVAIL EXPERIMENTALthrough a grade
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Figure 5ABCDVilli height (µm)5432a
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TRAVAIL EXPERIMENTALRESULTS1) Histo
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Figure 8ILEUM2.01.6TNF-αbbb2.52.0I
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TRAVAIL EXPERIMENTAL3) Intestinal i
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TRAVAIL EXPERIMENTALtreated group t
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TRAVAIL EXPERIMENTALThe potencial e
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TRAVAIL EXPERIMENTALQuantification
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Figure 10 :(a) Réaction de deesté
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TRAVAIL EXPERIMENTALrévélé de l
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TRAVAIL EXPERIMENTALABSTRACTFumonis
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TRAVAIL EXPERIMENTALintestinal leve
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TRAVAIL EXPERIMENTAL3) Experimental
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TRAVAIL EXPERIMENTALthe importance
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Figure 11 : Effects of FB1 and HFB1
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Table 15 : Effects of FB1 and HFB1
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Table 17 : Effects of FB1 and HFB1
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TRAVAIL EXPERIMENTALDISCUSSIONThe a
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TRAVAIL EXPERIMENTALassociated lymp
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TRAVAIL EXPERIMENTALHartinger et al
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Figure 13 :(a) Transformation par v
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Figure 14 :Illustrations de la proc
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Figure 15 :Plan expérimental de la
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TRAVAIL EXPERIMENTAL4) Analyses du
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TRAVAIL EXPERIMENTAL9) Analyses sta
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TRAVAIL EXPERIMENTALRESULTATS1) Eff
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TRAVAIL EXPERIMENTAL2) Effet des ag
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TRAVAIL EXPERIMENTALb,cca,ba,b,da,d
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TRAVAIL EXPERIMENTALL’exposition
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Figure 21 : Effet de l’exposition
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1,41,21,00,80,60,40,20,0IL‐8a,cc
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TRAVAIL EXPERIMENTALDISCUSSIONLes o
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Page 212 and 213: DISCUSSIONGENERALE160
Page 214 and 215: DISCUSSION GENERALEDans ce travail
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Page 220 and 221: DISCUSSION GENERALEet al., 2008b).
Page 222 and 223: DISCUSSION GENERALE• une réactio
Page 224 and 225: DISCUSSION GENERALE2. Les systèmes
Page 226 and 227: DISCUSSION GENERALEMycoplasma agala
Page 228 and 229: DISCUSSION GENERALEoptimale. Les au
Page 230 and 231: DISCUSSION GENERALEsphingomyéline
Page 232 and 233: DISCUSSION GENERALEsignalisation ce
Page 234 and 235: DISCUSSION GENERALEL’IMMUNITÉ IN
Page 236 and 237: DISCUSSION GENERALEplus spécifique
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Page 240 and 241: DISCUSSION GENERALELA CARBOXYLESTER
Page 242 and 243: DISCUSSION GENERALEde HFB1. Toutefo
Page 244 and 245: CONCLUSIONS184
Page 246 and 247: CONCLUSIONSLes effets d’expositio
Page 248 and 249: CONCLUSIONSest utilisée lorsque la
Page 250 and 251: REFERENCES BIBLIOGRAPHIQUESAABDEL-W
Page 252 and 253: REFERENCES BIBLIOGRAPHIQUESBHANDARI
Page 254 and 255: REFERENCES BIBLIOGRAPHIQUESCASADO,
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Page 258 and 259: REFERENCES BIBLIOGRAPHIQUESETIENNE,
Page 262 and 263: REFERENCES BIBLIOGRAPHIQUESHERZALLA
Page 264 and 265: REFERENCES BIBLIOGRAPHIQUESKERKADI,
Page 266 and 267: REFERENCES BIBLIOGRAPHIQUESKUMAR, M
Page 268 and 269: REFERENCES BIBLIOGRAPHIQUESMARZOCCO
Page 270 and 271: REFERENCES BIBLIOGRAPHIQUESODHAV, B
Page 272 and 273: REFERENCES BIBLIOGRAPHIQUESPFOHL-LE
Page 274 and 275: REFERENCES BIBLIOGRAPHIQUESREFAI, M
Page 276 and 277: REFERENCES BIBLIOGRAPHIQUESSCHWARTZ
Page 278 and 279: REFERENCES BIBLIOGRAPHIQUESSWANSON,
Page 280 and 281: REFERENCES BIBLIOGRAPHIQUESVEKIRU,
Page 282 and 283: REFERENCES BIBLIOGRAPHIQUESYAN, D.,
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