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Effet chez le porcelet d'une exposition à un régime co-contaminé en ...

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INTRODUCTIONABSTRACTMy<strong>co</strong>toxins are f<strong>un</strong>gal se<strong>co</strong>ndary metabolites that have be<strong>en</strong> associated with toxic effects inhuman and animal. The <strong>co</strong>ntamination of food and feed with my<strong>co</strong>toxins is a worldwide prob<strong>le</strong>m.Because of the detrim<strong>en</strong>tal effects of these my<strong>co</strong>toxins, a number of strategies have be<strong>en</strong> developedto prev<strong>en</strong>t the growth of my<strong>co</strong>toxig<strong>en</strong>ic f<strong>un</strong>gi and to de<strong>co</strong>ntaminate and/or detoxify my<strong>co</strong>toxin<strong>co</strong>ntaminated food and animal feed. These strategies include : 1) the prev<strong>en</strong>tion of my<strong>co</strong>toxin<strong>co</strong>ntamination, 2) detoxification of my<strong>co</strong>toxins pres<strong>en</strong>t in food and feed and 3) inhibition ofmy<strong>co</strong>toxin absorption in the gastrointestinal tract. The pres<strong>en</strong>t chapter mainly highlights processesinvolved in the se<strong>co</strong>nd point, <strong>co</strong>mmonly classified as physical and chemical methods, and which havebe<strong>en</strong> evaluated in the maize grain chain. Effici<strong>en</strong>cy and safety of these approaches are the maincriteria reported. Only a few of these methods are in practical use; this is probably due to thedifficulty to <strong>co</strong>mply with the FAO requirem<strong>en</strong>ts. In addition, no sing<strong>le</strong> method has the ability toremove simultaneously the wide variety of my<strong>co</strong>toxins which may <strong>co</strong>-occur in maize.51

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