Bulletin 2011/50 - European Patent Office
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Bulletin 2011/50 - European Patent Office

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(C07D) I.1(1)<br />

(74) Green, Mark Charles, Urquhart-Dykes & Lord<br />

LLP 3rd Floor 33 Glasshouse Street, London<br />

W1B 5DG, GB<br />

(51) C07D 241/44 (11) 2 393 787 A2*<br />

C07D 213/06 C07D 307/77<br />

C07D 221/18 A61K 31/498<br />

A61P 35/00 A61P 29/00<br />

(25) En (26) En<br />

(21) 10739256.5 (22) 09.02.2010<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MK MT<br />

NL NO PL PT RO SE SI SK SM TR<br />

(86) US 2010/023556 09.02.2010<br />

(87) WO 2010/091384 2010/32 12.08.2010<br />

(88) 24.03.<strong>2011</strong><br />

(30) 09.02.2009 US 151038 P<br />

(54) • CADHERIN-11-INHIBITOREN UND VER-<br />

FAHREN ZU DEREN ANWENDUNG<br />

• CADHERIN-11 INHIBITORS AND METH-<br />

ODS OF USE THEREOF<br />

• INHIBITEURS DE LA CADHÉRINE-11 ET<br />

MÉTHODES D'UTILISATION ASSOCIÉES<br />

(71) Georgetown University, 37th&O Streets, N.<br />

W., Washington, District Of Columbia 20057,<br />

US<br />

(72) BYERS, Stephen W., Tacoma Park, Maryland<br />

20912, US<br />

DAKSHANAMURTHY, Sivanesan, Herndon,<br />

Virginia 20170, US<br />

GUIDRY AUVIL, Jaime M., Elkridge, Maryland<br />

21075, US<br />

BROWN, Milton L., Brookeville, Maryland<br />

20833, US<br />

(74) Leissler-Gerstl, Gabriele, Hoefer & Partner<br />

<strong>Patent</strong>anwälte Pilgersheimer Strasse 20,<br />

81543 München, DE<br />

C07D 241/44 → (51) C07C 49/753<br />

C07D 261/04 → (51) C07D 207/18<br />

(51) C07D 261/08 (11) 2 393 788 A1*<br />

C07D 261/10 A61K 31/42<br />

(25) En (26) En<br />

(21) 10702131.3 (22) 02.02.2010<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MK MT<br />

NL NO PL PT RO SE SI SK SM TR<br />

(86) EP 2010/051251 02.02.2010<br />

(87) WO 2010/089297 2010/32 12.08.2010<br />

(30) 04.02.2009 EP 09152061<br />

04.02.2009 US 149721 P<br />

(54) • ISOXAZOL-5-CARBONSÄUREAMIDDERI-<br />

VATE<br />

• ISOXAZOLE-5-CARBOXAMIDE DERIVA-<br />

TIVES<br />

• DÉRIVÉS D'ISOXAZOLE-5-CARBOXAMIDE<br />

(71) N.V. Organon, Kloosterstraat 6, 5349 AB<br />

Oss, NL<br />

(72) RATCLIFFE, Paul, David, Newhouse Lanarkshire<br />

ML1 5SH, GB<br />

PALIN, Ronald, Newhouse Lanarkshire ML 1<br />

5SH, GB<br />

(74) Hussain, Deeba, et al, Merck Sharp & Dohme<br />

Limited Hertford Road, Hoddesdon Hertfordshire<br />

EN11 9BU, GB<br />

C07D 261/10 → (51) C07D 261/08<br />

(51) C07D 261/18 (11) 2 393 789 A1*<br />

C07D 413/06 C07D 413/12<br />

A61P 25/00 A61K 31/42<br />

A61K 31/422 A61K 31/45<br />

A61K 31/4468 A61K 31/4453<br />

A61K 31/4439 A61K 31/5377<br />

(25) En (26) En<br />

(21) 10703395.3 (22) 02.02.2010<br />

Europäisches <strong>Patent</strong>blatt<br />

<strong>European</strong> <strong>Patent</strong> <strong>Bulletin</strong><br />

<strong>Bulletin</strong> européen des brevets<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MK MT<br />

NL NO PL PT RO SE SI SK SM TR<br />

(86) US 2010/022869 02.02.2010<br />

(87) WO 2010/091009 2010/32 12.08.2010<br />

(30) 04.02.2009 US 149722 P<br />

04.02.2009 EP 09152068<br />

(54) • ISOXAZOL-3-CARBONSÄUREAMIDDERI-<br />

VATE<br />

• ISOXAZOLE-3-CARBOXAMIDE DERIVA-<br />

TIVES<br />

• DÉRIVÉS D'ISOXAZOLE-3-CARBOXAMIDE<br />

(71) N.V. Organon, Kloosterstraat 6, 5349 AB<br />

Oss, NL<br />

Pharmacopeia, LLC, 10275 Science Center<br />

Drive, San Diego, CA 92121, US<br />

(72) PALIN, Ronald, Newhouse Lanarkshire ML1<br />

5SH, GB<br />

RATCLIFFE, Paul, David, Newhouse Lanarkshire<br />

ML1 5SH, GB<br />

KULTGEN, Steven, G., Dayton New Jersey<br />

08810, US<br />

HO, Koc-Kan, West Windsor New Jersey<br />

085<strong>50</strong>, US<br />

ROUGHTON, Andrew, Laird, Port Hope<br />

Ontario L1A 2N4, CA<br />

OHLMEYER, Michael, Plainsboro New Jersey<br />

08536, US<br />

(74) Hussain, Deeba, et al, Merck Sharp & Dohme<br />

Limited Hertford Road, Hoddesdon Hertfordshire<br />

EN11 9BU, GB<br />

C07D 263/08 → (51) C07D 207/18<br />

C07D 277/08 → (51) C07D 207/18<br />

C07D 277/56 → (51) C07C 49/753<br />

(51) C07D 277/82 (11) 2 393 790 A1*<br />

C07D 487/04 A61K 31/<strong>50</strong>25<br />

A61P 35/00<br />

(25) Fr (26) Fr<br />

(21) 10708277.8 (22) 04.02.2010<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MK MT<br />

NL NO PL PT RO SE SI SK SM TR<br />

AL BA RS<br />

(86) FR 2010/0<strong>50</strong>177 04.02.2010<br />

(87) WO 2010/089<strong>50</strong>6 2010/32 12.08.2010<br />

(30) 06.02.2009 FR 0900510<br />

(54) • DERIVATE VON 6-(6-O-CYCLOALKYL-<br />

ODER -6-NH-CYCLOALKYLTRIAZOLOPY-<br />

RIDAZINSULFANYL) BENZOTHIAZOLEN<br />

UND BENZIMIDAZOLEN, DEREN HER-<br />

STELLUNG, DEREN VERWENDUNG ALS<br />

ARZNEIMITTEL UND DEREN VERWEN-<br />

DUNG ALS MET-INHBITIOREN<br />

• DERIVATIVES OF 6-(6-O-CYCLOALKYL OR<br />

6-NH-CYCLOALKYL-TRIAZOLOPYRIDA-<br />

ZINE-SULFANYL) BENZOTHIAZOLES AND<br />

BENZIMIDAZOLES, PREPARATION<br />

THEREOF, USE THEREOF AS DRUGS, AND<br />

USE THEREOF AS MET INHIBITORS<br />

• DERIVES DE 6-(6-O-CYCLOALKYL OU 6-<br />

NH-CYCLOALKYL-TRIAZOLOPYRIDAZINE-<br />

SULFANYL) BENZOTHIAZOLES ET BENZI-<br />

MIDAZOLES : PREPARATION, APPLICA-<br />

TION COMME MEDICAMENTS ET<br />

UTILISATION COMME INHIBITEURS DE<br />

MET<br />

(71) SANOFI, 174, Avenue de France, 7<strong>50</strong>13<br />

Paris, FR<br />

(72) BACQUE, Eric, F-7<strong>50</strong>13 Paris, FR<br />

NEMECEK, Conception, F-7<strong>50</strong>13 Paris, FR<br />

UGOLINI, Antonio, F-7<strong>50</strong>13 Paris, FR<br />

WENTZLER, Sylvie, F-7<strong>50</strong>13 Paris, FR<br />

RONAN, Baptiste, F-7<strong>50</strong>13 Paris, FR<br />

DAMOUR, Dominique, deceased, FR<br />

BARBALAT, Gilles, 7<strong>50</strong>13 Paris, FR<br />

74<br />

Anmeldungen<br />

Applications<br />

Demandes (<strong>50</strong>/<strong>2011</strong>) 14.12.<strong>2011</strong><br />

(74) Gaslonde, Aude, et al, Sanofi-Aventis<br />

Département Brevets 174, Avenue de France,<br />

7<strong>50</strong>13 Paris, FR<br />

(51) C07D 277/82 (11) 2 393 791 A1*<br />

C07D 487/04 A61K 31/<strong>50</strong>25<br />

A61P 35/00<br />

(25) Fr (26) Fr<br />

(21) 10708278.6 (22) 04.02.2010<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MK MT<br />

NL NO PL PT RO SE SI SK SM TR<br />

AL BA RS<br />

(86) FR 2010/0<strong>50</strong>178 04.02.2010<br />

(87) WO 2010/089<strong>50</strong>7 2010/32 12.08.2010<br />

(30) 06.02.2009 FR 0900512<br />

(54) • DERIVATE VON 6-(6-O-SUBSTITUIERTES<br />

TIRAZOLOPYRIDAZINSULFANYL)BENZO-<br />

THIAZOLEN UND BENZIMIDAZOLEN,<br />

DEREN HERSTELLUNG, DEREN VERWEN-<br />

DUNG ALS ARZNEIMITTEL UND DEREN<br />

VERWENDUNG ALS MET-INHIBITOREN<br />

• DERIVATIVES OF 6-(6-O-SUBSTITUTED-<br />

TRIAZOLOPYRIDAZINE-SULFANYL) BEN-<br />

ZOTHIAZOLES AND BENZIMIDAZOLES,<br />

PREPARATION THEREOF, USE THEREOF<br />

AS DRUGS, AND USE THEREOF AS MET<br />

INHIBITORS<br />

• DERIVES DE 6-(6-O-SUBSTITUE-TRIAZO-<br />

LOPYRIDAZINE-SULFANYL) BENZOTHIA-<br />

ZOLES ET BENZIMIDAZOLES :<br />

PREPARATION, APPLICATION COMME<br />

MEDICAMENTS ET UTILISATION COMME<br />

INHIBITEURS DE MET<br />

(71) SANOFI, 174, Avenue de France, 7<strong>50</strong>13<br />

Paris, FR<br />

(72) NEMECECK, Conception, F-7<strong>50</strong>13 Paris, FR<br />

UGOLINI, Antonio, F-7<strong>50</strong>13 Paris, FR<br />

WENTZLER, Sylvie, F-7<strong>50</strong>13 Paris, FR<br />

BACQUE, Eric, F-7<strong>50</strong>13 Paris, FR<br />

DAMOUR, Dominique, décédé, FR<br />

(74) Gaslonde, Aude, Sanofi Département Brevets<br />

174, avenue de France, 7<strong>50</strong>13 Paris, FR<br />

(51) C07D 277/82 (11) 2 393 792 A1*<br />

C07D 487/04 A61K 31/<strong>50</strong>25<br />

A61P 35/00<br />

(25) Fr (26) Fr<br />

(21) 10708279.4 (22) 04.02.2010<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MK MT<br />

NL NO PL PT RO SE SI SK SM TR<br />

AL BA RS<br />

(86) FR 2010/0<strong>50</strong>179 04.02.2010<br />

(87) WO 2010/089<strong>50</strong>8 2010/32 12.08.2010<br />

(30) 06.02.2009 FR 0900513<br />

(54) • DERIVATE VON 6-(6-NH-SUBSTITUIERTEN<br />

TRIAZOLOPYRIDAZINSULFANYL)BENZO-<br />

THIAZOLEN UND BENZIMIDAZOLEN,<br />

DEREN HERSTELLUNG, DEREN VERWEN-<br />

DUNG ALS ARZNEIMITTEL UND DEREN<br />

VERWENDUNG ALS MET-INHIBITOREN<br />

• DERIVATIVES OF 6-(6-NH-SUBSTITUTED-<br />

TRIAZOLOPYRIDAZINE-SULFANYL) BEN-<br />

ZOTHIAZOLES AND BENZIMIDAZOLES,<br />

PREPARATION THEREOF, USE THEREOF<br />

AS DRUGS, AND USE THEREOF AS MET<br />

INHIBITORS<br />

• DERIVES DE 6-(6-NH-SUBSTITUE-TRIA-<br />

ZOLOPYRIDAZINE-SULFANYL) BENZO-<br />

THIAZOLES ET BENZIMIDAZOLES :<br />

PREPARATION, APPLICATION COMME<br />

MEDICAMENTS ET UTILISATION COMME<br />

INHIBITEURS DE MET<br />

(71) SANOFI, 174, Avenue de France, 7<strong>50</strong>13<br />

Paris, FR<br />

(72) BACQUE, Eric, F-7<strong>50</strong>13 Paris, FR<br />

NEMECEK, Conception, F-7<strong>50</strong>13 Paris, FR

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