SPME Applications Guide - Overbrook Scientific

(New references added to the 7th edition are in bold) SPME Fiber /
Analyte / Extraction
Matrix Literature Reference Conditions Instrument
Determination of gamma-hydroxybutyrate in water and
949 g-Hydroxybutyrate human urine by SPME-GC/quadrupole iontrap MS GC-MS
in human urine J. Forensic Sci (2001), 46(3), 688-693
and water Blair, S.; Song, M.; Hall, B.; Brodbelt, J.
869 g-Hydroxybutyrate
Simple extraction of gamma-hydroxybutyrate in human whole
blood by headspace solid-phase microextraction
in human whole Jpn. J. Forensic Toxicol (2001) 19(1) 38-45
blood Kurihara, R; Ishii, A; Watanabe-Suzuki, K; Kumazawa, T;
Seno, H; Suzuki, O; Katsumata, Y
Determination of gamma-Hydroxybutyric Acid (GHB) in
405 g-Hydroxybutyric Plasma and Urine by Headspace SPME and GC-Positive 50µm Carbowax/TPR100 GC-PICI-MS
acid in Ion Chemical Ionization MS 70°C, 15 min
plasma, urine Rapid Commun. Mass Spec(2000) 14(24), 2401-2407 headspace
Frison, G; Tedeschi, L; Maietti, S; Ferrara, Santo D pH 6-7
323 1-Phenylethylamine
Simple Extraction of 1-Phenylethylamine in Human Urine
by Headspace SPME 65µm PDMS/DVB GC-NPD
in urine Jpn. J. Forensic Toxicol. 15(3): 189-193 (1997) 30 min @ 90°C
Ishii, A., Seno, H., Prosen, F., Watanabee, K., 10M NaOH, K2CO3
Kumanzawa, T., Hattori, H., Suzuki, O. headspace
324 Benzodiazepines
Detection of Benzodiazepines in Human Urine by
Direct Immersion SPME-GC 65µm PDMS/DVB GC-FID
in urine Jpn. J. Forensic Toxicol. 15 (1): 16-20 (1997)
Seno, H., Kumazawa, T., Ishii, A.,
30 min
Watanbe, K., Hattori, H., Suzuki, O. immersion
325 Benzodiazepines
Determination of Five Benzodiazepines in Aqueous
Solution and Biological Fluids, Using SPME with 65µm Carbowax/DVB GC-FID,
in water & urine Carbowax/DVB Fiber Coating 45°C, 60 min GC-MS
J. Microcolumn Sep. 10 (2): 193-201 (1998) stirring
Luo, Y., Pan, L., Pawliszyn, J. pH 7, salt added
351 Benzophenones
SPME and GC-ECD of Benzophenones for Detection of
Benzodiazepines in Urine 100µm PDMS GC-ECD
in urine J. Anal. Toxicology, Vol. 23, Jan/Feb 1999 , 54-61 30 min
Prosen, F., Seno, H., Ishii, A., Watanabe, K., immersion, stirring
Kumazawa, T., Hattori, H., Suzuki, O.
SPME-Microcolumn LC for the Analysis of Benzodiazepines
pH 9.4
KOH added
357 Benzodiazepines in Human Urine Carbowax/TPR100 HPLC-UV
in urine Analusis (1998), 26(5), M27-M30 60 min 220nm
Jinno, K., Taniguchi, M., Hayashida, M. immersion
Automated in-tube solid-phase microextraction coupled
779 Benzodiazepines with LC-electrospray ionization MS for the Supelco-Q capillary LC-ESI-MS
in urine & serum determination of selected benzodiazepines 60cmx0.25mm I.d.
J. Anal. Toxicology, (2000) Vol. 24(8),718-725
Yuan, H. ; Mester, Z.; Lord, H.; Pawliszyn, J.
SPME for Sample Preparation During Drug Metabolism Studies
326 Pharmazie 53 (3): 172-177 (1998)
Kroll, C., Borchert, H.
2739 Cyanide
An improved method for cyanide determination in blood using
SPMEand gas chromatography/mass spectrometry 75µm Carboxen GC-MS-SIM
in blood Rapid Commun. Mass Spectrom. 20, #19, 2932-2938 (2006-09-12)
Frison, G.; Zancanaro, F.; Favretto, D.; Ferrara, S. D.
headspace
328 Cyanide
Analysis of Cyanide in Blood by Headspace SPME and
Capillary GC Carbowax/DVB GC-NPD
in blood Chromatographia 47 (3/4): 209-214 (1998) 50°C, 45 min
Takekawa, K., Oya, M., Kido, A., Suzuki, O. headspace
Na2SO4 added
Ambient temperature, unless otherwise indicated. 122