Ergebnisbericht 2010/11 - Helmholtz-Zentrum für Infektionsforschung

162 WISSENSCHAFTLICHER ERGEBNISBERICHT | Veröffentlichungen
• Gemulla,G. & Pessler,F. (2011) Can norovirus infection lead to a
postinfectious arthritis? Report of 2 possible cases. Klinische Pädiatrie
223, 43-44.
• Schneider,J., Fricke,C., Overwin,H. & Hofer,B. (2011) High level expression
of a recombinant amylosucrase gene and selected properties
of the enzyme. Applied Microbiology and Biotechnology, in press.
• Akmatov,M., Mikolajczyk,R.T., Meier,S. & Krämer,A. (2011) Alcohol
consumption among university students in North Rhine-Westphalia,
Germany - results from a multicentre cross-sectional study. Journal
of American College Health, in press.
• Alberts,R. & Schughart,K. (2011) High throughput gene expression
analysis and the identifi cation of expression QTLs. In Gene Discovery
for Disease Models John Wiley & Sons, Inc., Hoboken, New Jersey,
USA, in press.
• Dai,L., Wei,X.N., Zheng,D.H., Mo,Y.Q., Pessler,F. & Zhang,B.Y. (2011)
Effective treatment of Kimura’s disease with lefl unomide in combination
with glucocorticoids. Clinical Rheumatology, in press.
• Hauck,F., Lee-Kirsch,M.A., Aust,D., Roesler,J. & Pessler,F. (2011)
Disarranged innate and adaptive humoral immune responses in
complement 2 defi ciency: treatment with rituximab. Arthritis Care
and Research (Hoboken), in press.
• Pessler,F. & Sherry,D.D. (2011) Rheumatic Fever. In The Merck
Manual, in press.
• von Jagwitz,M., Pessler,F. & Akmatov,M. (2011) Exhaled breath condensate
pH as risk factor for asthma in asymptomatic children with
prior wheezing. Journal of Allergy and Clinical Immunology, in press.
AG Systemorientierte Immunologie und Entzündungsforschung |
Prof. Dr. Ingo Schmitz
• Brandt,S., Ellwanger,K., Beuter-Gunia,C., Schuster,M., Hausser,A.,
Schmitz,I., & Beer-Hammer,S. (2010) SLy2 targets the nuclear
SAP30/HDAC1 complex. International Journal of Biochemistry and
Cell Biology 42, 1472-1481.
• Emadi,B.M., Soheili,Z.S., Schmitz,I., Sameie,S., & Schulz,W.A. (2010)
Snail regulates cell survival and inhibits cellular senescence in human
metastatic prostate cancer cell lines. Cell Biology and Toxicology
26, 553-567.
• Smith,A.J., Dai,H., Correia,C., Takahashi,R., Lee,S.H., Schmitz,I., &
Kaufmann,S.H. (2011) Noxa/Bcl-2 interactions contribute to bortezomib
resistance in human lymphoid cells. Journal of Biological
Chemistry, in press.
Abt. für Experimentelle Immunologie | Prof. Dr. Jochen Hühn
• Hubert,S., Rissiek,B., Klages,K., Hühn,J., Sparwasser,T., Haag,F.,
Koch-Nolte,F., Boyer,O., Seman,M., & Adriouch,S. (2010) Extracellular
NAD+ shapes the Foxp3+ regulatory T cell compartment through the
ART2-P2X7 pathway. Journal of Experimental Medicine 207, 2561-
2568.
• Humrich,J.Y., Morbach,H., Undeutsch,R., Enghard,P., Rosenberger,S.,
Weigert,O., Kloke,L., Heimann,J., Gaber,T., Brandenburg,S.,
Scheffold,A., Hühn,J., Radbruch,A., Burmester,G.R., & Riemekasten,G.
(2010) Homeostatic imbalance of regulatory and effector T cells due
to IL-2 deprivation amplifi es murine lupus. Proceedings of the National
Academy of Sciences of the United States of America 107, 204-209.
• Klages,K., Mayer,C.T., Lahl,K., Loddenkemper,C., Teng,M.W.,
Ngiow,S.F., Smyth,M.J., Hamann,A., Hühn,J., & Sparwasser,T. (2010)
Selective depletion of Foxp3+ regulatory T cells improves effective
therapeutic vaccination against established melanoma. Cancer
Research 70, 7788-7799.
• Mayer,C.T., Floess,S., Baru,A.M., Lahl,K., Hühn,J., & Sparwasser,T.
(2011) CD8(+) Foxp3(+) T cells share developmental and phenotypic
features with classical CD4(+) Foxp3(+) regulatory T cells but lack
potent suppressive activity. European Journal of Immunology 41, 716-
725.
• Menning,A., Loddenkemper,C., Westendorf,A.M., Szilagyi,B., Buer,J.,
Siewert,C., Hamann,A., & Hühn,J. (2010) Retinoic acid-induced gut
tropism improves the protective capacity of Treg in acute but not
in chronic gut infl ammation. European Journal of Immunology 40,
2539-2548.
• Polansky,J.K., Schreiber,L., Thelemann,C., Ludwig,L., Kruger,M.,
Baumgrass,R., Cording,S., Floess,S., Hamann,A., & Hühn,J. (2010)
Methylation matters: binding of Ets-1 to the demethylated Foxp3
gene contributes to the stabilization of Foxp3 expression in regulatory
T cells. Journal of Molecular Medicine 88, 1029-1040.
• Toker,A. & Hühn,J. (2011) To be or not to be a Treg cell: lineage decisions
controlled by epigenetic mechanisms. Science Signaling 4, e4.
AG Immunregulation | Priv.-Doz. Dr. Dunja Bruder
• Bar-On,L., Birnberg,T., Lewis,K.L., Edelson,B.T., Bruder,D., Hildner,K.,
Buer,J., Murphy,K.M., Reizis,B., & Jung,S. (2010) CX3CR1+ CD8alpha+
dendritic cells are a steady-state population related to plasmacytoid
dendritic cells. Proceedings of the National Acadamy of
Sciences of the United States of America 107, 14745-14750.
• Bruns,S., Kniemeyer,O., Hasenberg,M., Aimanianda,V., Nietzsche,S.,
Thywissen,A., Jeron,A., Latge,J.P., Brakhage,A.A., & Gunzer,M. (2010)
Production of extracellular traps against Aspergillus fumigatus in vitro
and in infected lung tissue is dependent on invading neutrophils
and infl uenced by hydrophobin RodA. PLoS Pathogens 6, e1000873.
• Liesz,A., Zhou,W., Mracskó,E., Karcher,S., Doerr,H., Schwarting,S.,
Sun,L., Bruder,D., Stegemann,S., Cerwenka,A., Sommer,C., Dalpke,A.,
& Veltkamp,R. (2011) Inhibition of lymphocyte traffi cking shields the
brain against deleterious neuroinfl ammation after stroke. Brain 134,
704-720.
• Hasenberg,M., Köhler,A., Jeron,A., Bonifatius,S., & Gunzer,M. (2011)
Direct observation of phagocytosis and NET formation by neutrophils
in infected lungs using 2-photon microscopy. Journal of Visualized
Experiments, in press.
• Tosiek,M.J., Gruber,A.D., Bader,S., Hoymann,H.G., Mauel,S.,
Tschwernig,T., Buer,J., Gereke,M., & Bruder,D. (2011) CD4+CD25+Foxp3+
regulatory T cells are dispensable for controlling CD8+ T cellmediated
lung infl ammation. Journal of Immunology, in press.
Abt. für System-Immunologie | Prof. Dr. Michael Meyer-Hermann
• Garin,A., Meyer-Hermann,M., Contie,M., Figge,M.T., Buatois,V.,
Gunzer,M., Toellner,K.M., Elson,G., & Kosco-Vilbois,M.H. (2010)
Toll-like receptor 4 signaling by follicular dendritic cells is pivotal for
germinal center onset and affi nity maturation. Immunity 33, 84-95.
• Jain,H.V. & Meyer-Hermann,M. (2010) The molecular asis of synergism
between carboplatin and ABT-737 therapy targeting ovarian
carcinomas. Cancer Research 71, 705-715.
• Kempf,H., Bleicher,M., & Meyer-Hermann,M. (2010) Spatio-temporal
cell dynamics in tumour spheroid irradiation. European Physical
Journal D 60, 177-193.
• Kobayashi,Y. & Telschow,A. (2010) Cytoplasmic feminizing elements
in a two-population model: infection dynamics, gene fl ow modifi cation,
and the spread of autosomal suppressors. Journal of Evolutionary
Biology 23, 2558-2568.
• Meyer-Hermann,M. & Benninger,R.K. (2010) A mathematical model
of beta-cells in an islet of Langerhans sensing a glucose gradient.
HFSP Journal 4, 61-71.