Artemisinin-based combination therapy for ... - The Cochrane Library

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Figure 7. How does Artemether-lumefantrine perform? Summary of primary outcome: Effectiveness: Total Failure (P. falciparum) Day PCR adjusted. Artemisinin-based combination therapy for treating uncomplicated malaria (Review) Copyright © 2009 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. 24
Figure 8. Olliaro-Vaillant plot. Day 28 PCR adjusted treatment failure data for trials of AL6 against all comparators are presented in this plot.The horizontal red line represents the WHO standard of 10% treatment failure (PCR corrected). Plots below this line represent trials where AL6 performed to this standard.The vertical blue line represents no difference between the two drugs. Plots to the right of this line represent trials where AL6 performed better than the comparator drug, and plots to the left represent trials where the comparator drug performed better than AL6. Artemisinin-based combination therapy for treating uncomplicated malaria (Review) Copyright © 2009 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. 25
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(Continued) Fofana 2005 Conference
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D A T A A N D A N A L Y S E S Compa
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2.2 Asia 1 317 Risk Ratio (M-H, Fix
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Comparison 5. Dihydroartemisinin-pi
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Comparison 8. Artesunate plus meflo
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Comparison 10. Artemether-lumefantr
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Comparison 12. Artesunate plus amod
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5.2 DHA-P 3 doses 3 1116 Risk Ratio
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Comparison 21. How does Artesunate
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Analysis 1.3. Comparison 1 Dihydroa
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Analysis 20.1. Comparison 20 How do
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Analysis 21.1. Comparison 21 How do
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(Continued) 2. How does artesunate
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(Continued) Sensitivity analysis 1
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(Continued) Smithuis 2004 MMR (652
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Dihydroartemisinin-piperaquine vs A
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Artesunate plus mefloquine vs Amodi
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PCR = polymerase chain reaction PCV
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Footnotes 1 Data were also availabl
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(Continued) justed Vivax efficacy:
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1 Dorsey 2006 UGA; Faye 2003 SEN; K
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