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Nutrition Science and Everyday Application - beta v 0.1

Nutrition Science and Everyday Application - beta v 0.1

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GLUCOSE REGULATION AND UTILIZATION IN THE BODY 197<br />

Figure 4.14. A mouse islet of Langerhans, visualized with immunofluorescent microscopy. In this<br />

image, cell nuclei are stained blue, insulin is stained red, <strong>and</strong> blood vessels are stained green. You<br />

can see that this islet is packed with insulin <strong>and</strong> sits right next to a blood vessel, so that it can<br />

secrete the two hormones, insulin <strong>and</strong> glucagon, into the blood. Glucagon is not stained in this<br />

image, but it’s there!<br />

In the figure below, you can see blood glucose <strong>and</strong> insulin throughout a 24-hour period,<br />

including three meals. You can see that when glucose rises, it is followed immediately by a<br />

rise in insulin, <strong>and</strong> glucose soon drops again. The figure also shows the difference between<br />

consuming a sucrose-rich food <strong>and</strong> a starch-rich food. The sucrose-rich food results in a<br />

greater spike in both glucose <strong>and</strong> insulin. Because more insulin is required to h<strong>and</strong>le that<br />

spike, it also causes a more precipitous decline in blood glucose. This is why eating a lot of<br />

sugar all at once may increase energy in the short-term, but soon after may make you feel<br />

like taking a nap!

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