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Nutrition Science and Everyday Application - beta v 0.1

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538 ALICE CALLAHAN, PHD, HEATHER LEONARD, MED, RDN, AND TAMBERLY POWELL, MS, RDN<br />

pain. 1 The body excretes little iron; therefore, the potential for toxicity from supplements is<br />

a concern. In children, death has occurred from ingesting as little as 200 mg of iron, so it is<br />

critical to keep iron supplements out of children’s reach. The tolerable upper intake for iron<br />

is 45 mg per day for adults, based on the amount that causes gastrointestinal distress. 1<br />

VITAMIN K<br />

Vitamin K refers to a group of fat-soluble vitamins that are similar in chemical structure. They<br />

act as coenzymes <strong>and</strong> have long been known to play an essential role in blood coagulation<br />

or clotting. Vitamin K is also required for maintaining bone health, as it modifies a protein<br />

which is involved in the bone remodeling process.<br />

Dietary Sources of Vitamin K<br />

Vitamin K is found in the highest concentrations in green vegetables such as collard <strong>and</strong><br />

turnip greens, kale, broccoli, <strong>and</strong> spinach. Soybean <strong>and</strong> canola oil are also common sources<br />

of vitamin K in the U.S. diet. 5 Additionally, vitamin K can be synthesized by bacteria in the<br />

large intestine, but the bioavailability of bacterial vitamin K is unclear.<br />

Figure 9.21. Dietary sources of vitamin K. Examples of good sources pictured include chard,<br />

spinach, kale, broccoli, <strong>and</strong> soybean oil. Source: NIH Office of Dietary Supplements<br />

Vitamin K Deficiency <strong>and</strong> Toxicity<br />

Vitamin K deficiency is rare, as most U.S. diets are adequate in vitamin K. 5 A deficiency in<br />

vitamin K causes excessive bleeding (or hemorrhage). When there is damage to a blood vessel

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