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Milk-and-Dairy-Products-in-Human-Nutrition-FAO

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Table 4.4 (cont<strong>in</strong>ued)<br />

Reference Dietary item Type of review Total CVD CHD Stroke Hypertension Ischaemic<br />

heart disease<br />

148<br />

Elwood et al.<br />

(2008)<br />

<strong>Milk</strong> (milk, whole milk,<br />

low-fat milk, high-fat<br />

milk); dairy products;<br />

dairy calcium<br />

Meta-analysis of 15<br />

studies (11 for heart<br />

disease, 7 for stroke)<br />

Reduced<br />

(RR = 0.79; 95%<br />

CI: 0.75–0.82)<br />

Reduced<br />

(RR = 0.83; 95%<br />

CI: 0.74–0.91)<br />

for milk;<br />

(RR = 0.84; 95%<br />

CI: 0.76–0.93)<br />

for milk/dairy<br />

Elwood et al.<br />

(2010)<br />

<strong>Milk</strong><br />

Systematic review.<br />

Meta-analysis of<br />

38 cohort studies.<br />

Five case-control<br />

retrospective studies<br />

also described but<br />

not <strong>in</strong>cluded <strong>in</strong> metaanalysis.<br />

Eleven cohorts<br />

for milk.<br />

Reduced<br />

(RR = 0.79; 95%<br />

CI: 0.68–0.91)<br />

Reduced<br />

(RR = 0.92; 95%<br />

CI: 0.80–0.99)<br />

Elwood et al.<br />

(2010)<br />

Elwood et al.<br />

(2010)<br />

Ralston et al.<br />

(2011)<br />

Butter<br />

Cheese<br />

Low-fat dairy<br />

Systematic review.<br />

Butter: 5 cohort studies<br />

(3 <strong>in</strong>cluded for metaanalysis)<br />

<strong>and</strong> several<br />

case-control studies<br />

Systematic review.<br />

Cheese: 6 cohort studies<br />

(2 <strong>in</strong>cluded for metaanalysis)<br />

Systematic review <strong>and</strong><br />

meta-analysis of 5<br />

cohorts<br />

3 cohort studies<br />

suggest a possible<br />

reduction <strong>in</strong> vascular<br />

disease risk (RR = 0.93;<br />

95% CI: 0.84–1.02),<br />

while 2 cross-sectional<br />

studies suggest an<br />

<strong>in</strong>crease <strong>and</strong> 1 an<br />

<strong>in</strong>crease <strong>in</strong> peripheral<br />

arterial disease<br />

Us<strong>in</strong>g a fixed<br />

effects model, <strong>and</strong><br />

weight<strong>in</strong>g the studies<br />

appropriately: overall<br />

estimate of risk for<br />

vascular disease<br />

decreased (RR = 0.90;<br />

95% CI: 0.79–1.03)<br />

Reduced<br />

(RR = 0.84; 95%<br />

CI: 0.74–0.95)<br />

<strong>Milk</strong> <strong>and</strong> dairy products <strong>in</strong> human nutrition

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