28.01.2015 Views

Milk-and-Dairy-Products-in-Human-Nutrition-FAO

Milk-and-Dairy-Products-in-Human-Nutrition-FAO

Milk-and-Dairy-Products-in-Human-Nutrition-FAO

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

158<br />

<strong>Milk</strong> <strong>and</strong> dairy products <strong>in</strong> human nutrition<br />

The conclusions of Lampe (2011), that “meta-analyses of cohort data available to<br />

date support an <strong>in</strong>verse association between milk <strong>in</strong>take <strong>and</strong> risk of colorectal <strong>and</strong><br />

bladder cancer <strong>and</strong> a positive association between diets high <strong>in</strong> calcium <strong>and</strong> risk<br />

of prostate cancer”, <strong>and</strong> of Aune et al. (2012), “that milk <strong>and</strong> total dairy products,<br />

but not cheese or other [<strong>in</strong>dividual] dairy products, are associated with a reduction<br />

<strong>in</strong> colorectal cancer risk”, were consistent with those of WCRF <strong>and</strong> AICR (2007,<br />

2008a, 2008b). With regard to bladder cancer, while Mao et al. (2011) concluded that<br />

milk may be related to the reduction of bladder cancer risk, Li et al. (2011) reported<br />

that their f<strong>in</strong>d<strong>in</strong>gs were not supportive of an <strong>in</strong>dependent relationship between the<br />

<strong>in</strong>take of milk or dairy products <strong>and</strong> the risk of bladder cancer. Both Mao et al.<br />

(2011) <strong>and</strong> Li et al. (2011) observed differences between geographical areas, which<br />

may reflect the different compositions of dairy products consumed <strong>in</strong> different<br />

parts of the world or ethnic differences; this warrants further research. Other areas<br />

where further research is needed <strong>in</strong>clude the effect of specific dairy products <strong>and</strong><br />

constituents of dairy products such as rumen-derived metabolites <strong>and</strong> live microbes<br />

present <strong>in</strong> some dairy products on cancer risk.<br />

4.10 <strong>Milk</strong> hypersensitivity<br />

Hypersensitivity to milk may be attributed to either lactose or prote<strong>in</strong> <strong>in</strong> milk<br />

(Figure 4.2). Sensitivity to cow-milk prote<strong>in</strong> causes vary<strong>in</strong>g degrees of <strong>in</strong>jury to the<br />

<strong>in</strong>test<strong>in</strong>al mucosal surface (Heyman, 2006). In contrast, <strong>in</strong>gestion of dairy products<br />

result<strong>in</strong>g <strong>in</strong> symptoms of lactose <strong>in</strong>tolerance generally leads to transient symptoms<br />

without caus<strong>in</strong>g harm to the gastro<strong>in</strong>test<strong>in</strong>al tract (Heyman, 2006).<br />

figure 4.2<br />

<strong>Milk</strong> hypersensitivity: difference between milk allergy <strong>and</strong> <strong>in</strong>tolerance<br />

<strong>Milk</strong><br />

hypersensitivity<br />

Immunological<br />

Non<br />

immunological<br />

Antibody<br />

mediated<br />

<strong>Milk</strong> prote<strong>in</strong><br />

allergy<br />

Lactose<br />

<strong>in</strong>tolerance<br />

Source: Adapted from Johansson et al., 2001 <strong>and</strong> Monaci et al., 2006.

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!