Milk-and-Dairy-Products-in-Human-Nutrition-FAO
Milk-and-Dairy-Products-in-Human-Nutrition-FAO
Milk-and-Dairy-Products-in-Human-Nutrition-FAO
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206<br />
<strong>Milk</strong> <strong>and</strong> dairy products <strong>in</strong> human nutrition<br />
Table 4.8 (cont<strong>in</strong>ued)<br />
Benefits<br />
Risks<br />
Weight ga<strong>in</strong> <strong>and</strong> obesity development<br />
Observational evidence does not support the hypothesis<br />
that dairy fat contributes to obesity.<br />
There may be a protective effect of milk <strong>and</strong> dairy on<br />
weight due to components such as prote<strong>in</strong>. However, if<br />
such an effect exists the magnitude is likely to be small.<br />
<strong>Dairy</strong> is a dense energy source <strong>and</strong> energy balance is<br />
critical to ma<strong>in</strong>ta<strong>in</strong><strong>in</strong>g healthy body weight.<br />
Cross-sectional epidemiological studies <strong>in</strong>dicate that<br />
high dairy food <strong>in</strong>take can contribute to weight management,<br />
but prospective studies <strong>and</strong> r<strong>and</strong>omized<br />
controlled <strong>in</strong>tervention trials have yielded <strong>in</strong>consistent<br />
results.<br />
Whether dairy consumption <strong>in</strong> childhood has an etiologic<br />
role <strong>in</strong> the development of obesity <strong>in</strong> later life is<br />
an open area of discussion.<br />
Metabolic syndrome <strong>and</strong> type 2 diabetes<br />
There is moderate evidence show<strong>in</strong>g an association<br />
between milk <strong>and</strong> dairy product consumption <strong>and</strong><br />
lower <strong>in</strong>cidence of T2DM <strong>in</strong> adults.<br />
Some studies suggest that dairy food consumption may<br />
have a beneficial impact on some MetS components.<br />
There is limited evidence demonstrat<strong>in</strong>g that milk<br />
<strong>and</strong> dairy product consumption is associated with the<br />
reduced risk of MetS.<br />
Cardiovascular disease<br />
Although dairy foods contribute to SFA content of the<br />
diet, other components <strong>in</strong> milk such as calcium <strong>and</strong><br />
PUFAs may reduce risk factors for CHD.<br />
The majority of review studies conduct<strong>in</strong>g meta-analyses<br />
of prospective studies conclude that low-fat milk<br />
<strong>and</strong> total dairy product consumption is generally not<br />
associated with CVD risk, <strong>and</strong> may actually contribute<br />
to a reduction of CVD.<br />
Results for full-fat dairy <strong>and</strong> CVD risk are mixed.<br />
<strong>Dairy</strong> products conta<strong>in</strong> SFAs. SFAs may <strong>in</strong>crease LDL<br />
cholesterol <strong>and</strong> risk of CVD.<br />
Industrial trans fatty acids are associated with an<br />
<strong>in</strong>creased risk of CHD. The evidence regard<strong>in</strong>g rum<strong>in</strong>ant<br />
trans fats <strong>and</strong> CVD risk is <strong>in</strong>conclusive.<br />
Cancer<br />
Some components <strong>in</strong> milk <strong>and</strong> dairy products such<br />
as calcium, vitam<strong>in</strong> D (fortified milk), sph<strong>in</strong>golipids,<br />
butyric acid <strong>and</strong> milk prote<strong>in</strong>s may be protective<br />
aga<strong>in</strong>st cancer.<br />
<strong>Milk</strong> <strong>and</strong> calcium probably protect aga<strong>in</strong>st colorectal<br />
cancer.<br />
Limited evidence suggests that milk protects aga<strong>in</strong>st<br />
bladder cancer.<br />
Childhood milk consumption may have an effect on<br />
subsequent cancers <strong>in</strong> adulthood via the IGF-1 axis.<br />
Limited evidence suggest<strong>in</strong>g that cheese is a cause of<br />
colorectal cancer.<br />
Diets high <strong>in</strong> calcium <strong>and</strong> high consumption of milk<br />
<strong>and</strong> dairy may be a cause of prostate cancer.<br />
<strong>Milk</strong> hypersensitivity<br />
Lactose is the pr<strong>in</strong>cipal carbohydrate <strong>in</strong> milk. Lactose<br />
malabsorption (or maldigestion) caused by low lactase<br />
levels manifests as lactose <strong>in</strong>tolerance. Accord<strong>in</strong>g to<br />
some estimates, approximately 70% of the world’s<br />
population has primary lactase deficiency.<br />
Incidence of CMA is reported to fall between 2% <strong>and</strong><br />
6% worldwide. <strong>Milk</strong> from other animal species such<br />
as goat, sheep, <strong>and</strong> buffalo should also be avoided by<br />
those with CMA.<br />
CHD – coronary heart disease; CMA – cow-milk allergy; CVD – cardiovascular disease; IGF – <strong>in</strong>sul<strong>in</strong>-like growth factor;<br />
LDL – low-density lipoprote<strong>in</strong>; PUFAs – polyunsaturated fatty acids; SFA – saturated fatty acid; T2DM – type 2 diabetes mellitus.