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Milk-and-Dairy-Products-in-Human-Nutrition-FAO

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Table 7.1 (cont<strong>in</strong>ued)<br />

ASIA AND PACIFIC<br />

Country/organization<br />

Title (duration)<br />

Reference<br />

India/Center for<br />

Micronutrient Research<br />

<strong>in</strong> India/Johns Hopk<strong>in</strong>s<br />

Bloomberg School of<br />

Public Health<br />

Efficacy of fortified milk<br />

on morbidity<br />

(2002–2004)<br />

Sazawal et al. (2007)<br />

Indonesia/Johns Hopk<strong>in</strong>s<br />

University<br />

Consumption of<br />

iron-fortified milk <strong>and</strong><br />

noodles<br />

(1999–2003)<br />

Semba et al. (2010)<br />

Target<br />

population<br />

Goal/ objective<br />

1–3 yrs Evaluate efficacy<br />

of micronutrient<br />

fortified milk<br />

on morbidity<br />

outcomes<br />

(diarrhoea, acute<br />

respiratory illness)<br />

6–59 mo Determ<strong>in</strong>e<br />

the level of<br />

risk reduction<br />

for anaemia<br />

associated with<br />

consumption of<br />

iron-fortified milk<br />

<strong>and</strong> noodles<br />

Intervention:<br />

strategy <strong>and</strong> activities<br />

Intervention group:<br />

fortified milk with iron<br />

(9.6 mg), z<strong>in</strong>c (7.8 mg),<br />

selenium (4.2 µg), copper<br />

(0.27 mg), vit A (156 µg),<br />

vit C (40.2 mg), <strong>and</strong> vit E<br />

(7.5 mg)<br />

*Families participat<strong>in</strong>g <strong>in</strong><br />

<strong>Nutrition</strong>al Surveillance<br />

System (NSS) of M<strong>in</strong>istry<br />

of Health <strong>and</strong> Helen<br />

Keller International<br />

*Child consumption<br />

of milk or noodles <strong>in</strong><br />

the previous week <strong>and</strong><br />

commercial br<strong>and</strong> of<br />

product documented<br />

*HemoCue used to<br />

measure haemoglob<strong>in</strong><br />

<strong>in</strong> children<br />

Design:<br />

comparison groups<br />

<strong>and</strong> methods<br />

R<strong>and</strong>omised, double-bl<strong>in</strong>ded<br />

controlled trial <strong>in</strong> peri-urban<br />

region of northern India<br />

Intervention group: fortified<br />

milk for one year (n=316)<br />

Control group: non-fortified<br />

milk for one year (n=317)<br />

Observational study us<strong>in</strong>g<br />

stratified, multistage cluster<br />

sampl<strong>in</strong>g to collect survey<br />

data over 17 rounds; multiple<br />

logistic regression models<br />

used to exam<strong>in</strong>e determ<strong>in</strong>ants<br />

(fortified milk <strong>and</strong> noodles) of<br />

child anaemia<br />

4 800 urban households <strong>and</strong><br />

1 560 rural households<br />

Level of Inference<br />

Results<br />

Probability<br />

*Odds of days with severe illness<br />

reduced by 15%, <strong>in</strong>cidence of<br />

diarrhoea by 18%, <strong>and</strong> <strong>in</strong>cidence<br />

of acute lower respiratory illness<br />

by 26%<br />

*Greater benefits observed <strong>in</strong><br />

younger children (≤24 mo)<br />

Plausibility<br />

*Children showed significantly<br />

lower risk of anaemia associated<br />

with consumption of fortified<br />

milk <strong>in</strong> both rural <strong>and</strong> urban<br />

areas, adjusted OR: 0.76; 95%<br />

CI: 0.72, 0.80 (P

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