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Tobacco and Public Health - TCSC Indonesia

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to tobacco product ingredients <strong>and</strong> emissions, so to should the reinforcing effects of<br />

tobacco products be influenced by the ingredients <strong>and</strong> emissions of tobacco products.<br />

Just as it should be possible to reduce cigarette toxicity even short of eliminating<br />

toxicity, it may be possible to reduce tobacco addictiveness even without eliminating<br />

the nicotine or eliminating addiction potential (Henningfield <strong>and</strong> Zeller 2003; World<br />

<strong>Health</strong> Organization 2003). Behavioral pharmacological analyses may then prove to be<br />

as important as toxicology studies in guiding the regulation of tobacco product ingredients<br />

<strong>and</strong> emissions.<br />

Acknowledgments<br />

Preparation of this paper was supported, in part, by a Robert Wood Johnson<br />

Foundation Emerging Leadership Program Award to B.E. Garrett, <strong>and</strong> a Robert Wood<br />

Johnson Foundation Innovators Combating Substance Abuse Award to<br />

J.E. Henningfield. J.E. Henningfield provides consulting services regarding treatments<br />

for tobacco dependence to GlaxoSmithKline Consumer <strong>Health</strong> Care through Pinney<br />

Associates. J.E. Henningfield also has a financial interest in a nicotine replacement<br />

product under development, <strong>and</strong> serves as an expert witness in litigation against the<br />

tobacco industry by the U.S. Department of Justice <strong>and</strong> other plaintiffs. We greatly<br />

appreciate the editorial assistance of Christine A. Rose, whose efforts were supported<br />

by the Innovators award to JEH.<br />

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