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Tobacco and Public Health - TCSC Indonesia

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Table 22.2 Results from selected case–control studies on smoking <strong>and</strong> risk of adenocarcinoma of the oesophagus<br />

Reference <strong>and</strong> Type of controls OR for current Dose Duration<br />

location Cases:controls <strong>and</strong> former smokers Cutpoints OR 1 Cutpoints OR 1<br />

North America<br />

Brown et al. Population Current < 205 1.1 (0.5–2.4) 42 2.4 (1.5–3.7)<br />

Wu et al. 2001— Population Current Former<br />

Los Angeles county, 222 ACO:1356 OR = 2.8 (1.8–4.3) 1–195 1.2 (0.8–2.0) ≤ 20 yrs 1.4 (0.9–2.2)<br />

USA Former ≥ 20 1.7 (1.1–2.5) 21–40 2.1 (1.4–3.1)<br />

OR = 1.5 (1.0–2.2) Current ≥ 41 2.2 (1.3–3.5)<br />

1– 1.6 (0.7–3.3)<br />

20–39 2.9 (1.8–4.8)<br />

≥ 40 4.5 (2.3–8.7)<br />

Europe<br />

Levi et al. Barrett’s oesophagus (BE) 25 0.9 (0.3–2.9)<br />

Menke-Pluymers et al. BE Current<br />

1993—Rotterdam, The 62 ACO in BE: OR = 2.3 7 (p < 0.05)<br />

Netherl<strong>and</strong>s 96 Co with BE

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