Tobacco and Public Health - TCSC Indonesia

Table 34.8 Cohort studies that reported results on Alzheimer’s disease and smoking*
Study Country Number Total number of subjects Gender Relative risk in current smokers
of subjects with Alzheimer’s disease compared to never-smokers (95% CI)
Doll et al. 2000 UK 24 133 370 Men 0.99 (0.78–1.25)
Hebert et al. 1992 USA 513 76 Men and women 0.7 (0.3–1.4)
Hirayama et al. 1992 Japan 265 118 120 Men and women 1.61 (1.01–2.56)
Katzman et al. 1989 USA 434 32 Men and women 0.27 (0.11–0.61)
Launer et al. 1999 Europe # 16 334 277 Men and women 1.74 (1.21–2.50)
Merchant et al. 1999 USA 2128 142 Men and women 1.02 (0.60–1.50)
Ott et al. 1998 Netherlands 6870 105 Men and women 1.70 (0.60–1.50)
Wang et al. 1999 Sweden 343 34 Men and women 1.1 (0.5–2.4)
*Adapted from Almeida et al. 2002.
# Denmark, France, Netherlands, and UK.