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Tobacco and Public Health - TCSC Indonesia

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world tobacco burden (World <strong>Health</strong> Organization 1997). In the US, 4.2 pounds of<br />

tobacco were consumed per person in 1999: 83% in cigarettes, 6% in cigars, 5% as<br />

snuff, 5% as chewing tobacco, <strong>and</strong> 1% as smoking tobacco (Giovino 2002).<br />

Commercial cigarettes<br />

<strong>Tobacco</strong><br />

MIRJANA V. DJORDJEVIC 183<br />

Unlike systematic monitoring <strong>and</strong> reporting of emissions of nicotine, tar, <strong>and</strong> carbon<br />

monoxide in the mainstream smoke (MS) of cigarettes (e.g. U.S. Federal Trade<br />

Commission 2000), there is no official requirement, in any country in the world, for<br />

the reporting on nicotine content in the tobacco blend of commercial products. The<br />

latter is especially puzzling since the chemical composition of cigarette smoke (both<br />

qualitative <strong>and</strong> quantitative), as well as addictive <strong>and</strong> carcinogenic properties of any<br />

given product, depend directly on the profile of preformed tobacco constituents.<br />

The data in Table 9.1 show an international comparison of the levels of nicotine,<br />

nitrate, <strong>and</strong> the two carcinogenic, nicotine-derived, N-nitrosamines in commercial<br />

cigarette tobacco. The assays of a large number of br<strong>and</strong>s from the US, Canada, the<br />

United Kingdom (UK), Japan, <strong>and</strong> other countries have demonstrated that there is a<br />

wide variation in concentrations of nicotine in the tobacco filler (from 7.2 to 23.5 mg/g<br />

tobacco), as well as concentrations of nitrate (from 0.3 to 20.6 mg/cigarette), NNN<br />

(from 45-58 000 ng/g tobacco), <strong>and</strong> NNK (from not detected to 10 745 ng/cigarette;<br />

detection limit

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