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Tobacco and Public Health - TCSC Indonesia

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586<br />

CHRONIC OBSTRUCTIVE PULMONARY DISEASE<br />

Excess Death Rate per 100,000<br />

1200<br />

1000<br />

800<br />

600<br />

400<br />

200<br />

Lung Cancer<br />

CHD<br />

COPD<br />

0<br />

35–39 40–44 45–49 50–54 55–59 60–64 65–69 70–74 75–79<br />

CPS II Data (Thun et al. 1997)<br />

Age Group<br />

Fig. 33.2 Male excess death rates* from smoking-caused diseases (*rates in smokers minus<br />

the rate in never smokers). Excess rates are calculated by subtracting the age-specific death<br />

rate for a given disease experienced by smokers from that for never smokers in the American<br />

Cancer Society Cancer Prevention Study II as published by Thun et al. (1997). Rates are<br />

presented for male smokers.<br />

COPD to decline following cessation, <strong>and</strong> the death rate remains substantially elevated<br />

in former smokers even after 20 years of abstinence.<br />

As described above, lung function may improve slightly following cessation probably<br />

due to a decrease in airway inflammation once the exposure to the irritants in tobacco<br />

smoke ceases. The rate of lung function decline with advancing age also slows following<br />

cessation <strong>and</strong> returns to that of the never smoker (Anthonisen et al. 1994; Scanlon<br />

et al. 2000). However, the emphysema present in the lung at the time of cessation does<br />

not repair, <strong>and</strong> lung function rarely returns to normal among smokers with substantial<br />

lung injury at the time of cessation.<br />

Respiratory symptoms, most notably a chronic productive cough, often improve<br />

following cessation <strong>and</strong> may disappear altogether.<br />

Pipe <strong>and</strong> cigar smoking<br />

Cigarette smokers are much more likely to inhale tobacco smoke than are those who<br />

have only smoked pipes <strong>and</strong> cigars, <strong>and</strong> this distinction is evident in the pattern of<br />

disease risks found among smokers of different forms of tobacco. Pipe <strong>and</strong> cigar smokers<br />

have risks similar to those of cigarette smokers for cancers of the oral cavity where

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