Tobacco and Public Health - TCSC Indonesia

Table 34.3 Studies that reported results on Crohn’s disease and smoking*
Study Country Total number of subjects Gender Relative risk in current smokers
with Crohn’s disease compared to never-smokers (95% CI)
Case–control
Logan et al. 1984, 1986 UK 131 Men and women 4.2 (2.5–6.8)
Tobin et al. 1987 UK 127 Men and women 3.2 (1.9–5.5)
Franceschi et al. 1987 Italy 109 Men and women 2.9 (1.8–4.9)
Lindberg et al. 1988 Sweden 144 Men and women 2.2 (1.4–3.3)
Benoni and Nilsson 1987 Sweden 155 Men and women 2.0 (1.3–3.1)
Calkins et al. 1984 USA 132 Men and women 2.1 (1.2–3.5)
Sandler and Holland 1988 USA 298 Men and women 1.9 (1.3–2.8)
Combined – 1096 Men and women 2.4 (2.0–2.9)
Cohort
Vessey et al. 1986 UK 18/17 032 Women 3.0 (1.0–9.0) #
Logan et al. 1986, 1989 UK 42/>20 000 Women 1.75 (0.93–3.3) #
*Adapted from Logan (1990).
# Current smokers compared to never and ex-smokers (relative risk adjusted for age, social class, and oral contraceptive use).