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Tobacco and Public Health - TCSC Indonesia

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Table 20.1 Summary of results of case–control studies on prostate cancer in relation to cigarette smoking<br />

Investigator(s) Location No. of subjects Major findings<br />

Schwartz et al. 1961 Paris, France 139 cases No association. 79% <strong>and</strong> 73% of smokers among cases<br />

139 hospital controls <strong>and</strong> controls, respectively<br />

Wynder et al. 1971 New York, U.S. 300 cases No association. 40% <strong>and</strong> 39% of cigarette smokers among<br />

400 hospital controls cases <strong>and</strong> controls, respectively<br />

Kolonel <strong>and</strong> Winkelstein New York, U.S. 176 cases No significant association. a Ever smokers: OR = 1.1<br />

1977 269 hospital controls (noncancer controls), OR = 1.0 (cancer controls)<br />

Schuman et al. 1977 Minneapolis, U.S. 40 cases Direct association, when neighborhood, but not hospital<br />

43 hospital controls, were used<br />

35 neighborhood controls<br />

Williams <strong>and</strong> Horm 1977 U.S. (Third Nat. Cancer 257 cases No association. No of cigarette smoked: 1-400/year,<br />

controls survey) 1116 population controls OR = 0.7; 401–800/year, OR = 0.7; >800/year, OR = 0.9.<br />

Niijima <strong>and</strong> Koiso 1980 Japan 187 cases No association<br />

200 hospital controls<br />

Mishina et al. 1985 Kyoto, Japan 111 cases No significant association. a Ever smokers: RR = 1.6<br />

100 population controls<br />

Checkoway et al. 1987 Chapel Hill, U.S. 40 cases No association<br />

64 hospital controls<br />

Ross et al. 1987 Los Angeles, U.S. 284 cases (142 blacks <strong>and</strong> 142 whites) No association. a Ever smokers:<br />

284 population controls Whites, RR =1.1; Blacks, RR = 0.9<br />

(142 blacks <strong>and</strong> 142 whites)<br />

Honda et al. 1988 California, U.S. 216 cases Ever smokers: RR = 1.9; years of smoking: >40, RR = 2.6<br />

212 population controls<br />

Yu et al. 1988 U.S. 1162 cases (989 whites <strong>and</strong> 161 blacks) No significant association. a Whites: ex-smokers OR = 0.9;<br />

3124 hospital controls current smokers OR = 1.0. Blacks: ex-smokers OR = 1.4;<br />

(2791 whites <strong>and</strong> 320 blacks) current smokers OR = 1.7

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