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Tobacco and Public Health - TCSC Indonesia

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evidence have proved to be effective tools for translating the findings on smoking, both<br />

active <strong>and</strong> passive, <strong>and</strong> disease into policy.<br />

The issue of passive smoking <strong>and</strong> health has a briefer history. Some of the first<br />

epidemiological studies on second-h<strong>and</strong> smoke or environmental tobacco smoke<br />

(ETS) <strong>and</strong> health were reported in the late 1960s (Cameron 1967; Colley <strong>and</strong> Holl<strong>and</strong><br />

1967; Cameron et al. 1969). Prior to that point, there had been scattered case reports,<br />

the Nazi government had campaigned against smoking in public, <strong>and</strong> one German<br />

physician, Fritz Lickint, used the term ‘passive smoking’ in his 1939 book on smoking<br />

(Proctor 1995). In the 1960s, the initial investigations focused on parental smoking <strong>and</strong><br />

lower respiratory illnesses in infants; studies of lung function <strong>and</strong> respiratory symptoms<br />

in children soon followed (US Department of <strong>Health</strong> <strong>and</strong> Human Services 1986;<br />

Samet <strong>and</strong> Wang 2000). The 1971 report of the U.S. Surgeon General raised concern<br />

about possible adverse effects of passive smoking (US Department of <strong>Health</strong> Education<br />

<strong>and</strong> Welfare 1971).<br />

The first major studies on passive smoking <strong>and</strong> lung cancer in nonsmokers were<br />

reported in 1981, a cohort study in Japan <strong>and</strong> a case–control study in Athens (Hirayama<br />

1981a, b;Trichopoulos et al. 1981), <strong>and</strong> by 1986 the evidence supported the conclusion<br />

that passive smoking was a cause of lung cancer in non-smokers, a conclusion reached<br />

by the International Agency for Research on Cancer (IARC), the U.S. Surgeon General,<br />

<strong>and</strong> the U.S. National Research Council (IARC 1986; US Department of <strong>Health</strong> <strong>and</strong><br />

Human Services 1986). The evidence on child health <strong>and</strong> passive smoking was also<br />

reviewed in 1986 by the U.S. Surgeon General <strong>and</strong> the U.S. National Research Council<br />

(Table 17.1). A now-substantial body of evidence has continued to identify new<br />

diseases <strong>and</strong> other adverse effects of passive smoking, including increased risk for<br />

coronary heart disease (Table 17.1) (California Environmental Protection Agency<br />

1997; Scientific Committee on <strong>Tobacco</strong> <strong>and</strong> <strong>Health</strong> & HSMO 1998; WHO 1999; Samet<br />

<strong>and</strong> Wang 2000).<br />

In Australia <strong>and</strong> New Zeal<strong>and</strong>, the United Kingdom, some countries of Sc<strong>and</strong>inavia,<br />

<strong>and</strong> the United States, for example, the evidence of harm to nonsmokers from breathing<br />

secondh<strong>and</strong> smoke has led to the implementation of national <strong>and</strong> local policies<br />

<strong>and</strong> regulation to restrict smoking in public places <strong>and</strong> workplaces (National Cancer<br />

Institute 1999; Corrao et al. 2000). In the state of California in the U.S., all workplaces,<br />

including bars <strong>and</strong> restaurants, are now smokefree. Smoking is no longer permitted on<br />

international airplane flights. There are abundant successful examples of using the<br />

scientific evidence on passive smoking as the foundation for effective public policies<br />

for reducing exposure.<br />

Toxicology of tobacco smoke<br />

JONATHAN M. SAMET 289<br />

<strong>Tobacco</strong> smoke is generated by the burning of a complex organic material, tobacco,<br />

along with the various additives <strong>and</strong> paper, at a high temperature, reaching about

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