Faglig rapport 2005 - Helse Vest

og om disse proteinene kan utnyttes til å lage bedre diagnostiske metoder, bedre vaksiner mottuberkulose og om de egner seg som mål for nye antibiotika.1 vitenskapelige artikler er publisert i 2005 (PubMed registrert):Charlet D, Mostowy S, Alexander D, Sit L, Wiker HG, Behr MA"Reduced expression of antigenic proteins MPB70 and MPB83 in Mycobacterium bovisBCG strains due to a start codon mutation in sigK."Mol Microbiol. 2005;56(5):1302-13PMID: 158824227 forskningspublikasjoner (inkl. abstracts) er publisert i 2005:Målen, H. and Wiker H. G."Identification of N-terminal peptides by MALDI-TOF of processed proteins secreted through the general secretory pathway"National Proteomics meeting 18.-19. May 2005, BBB Building, University of Bergen, Bergen, NorwayMålen, H. and Wiker H. G."Identification of N-terminal peptides by MALDI-TOF of processed proteins secreted through the general secretory pathway"Fighting infection. Joint meeting: Society for general microbiology UK; Society for Medical Microbiology Norway; Society forMicrobiology, Norway, Society for Virology, Norway; 27-30 september 2005; Radisson SAS Hotel, Bergen, NorwayWiker, H. G."Plenary lecture: The secreted proteomes of Mycobacterium tuberculosis and Mycobacterium leprae"Proceedings of International Conference on Functional genomics for novel vaccine and drug design against mycobacterialinfection. February 10-11, 2005 Indian Institute of Technology, Kharagpur, IndiaWiker, H. G."Predicting proteins exported through the general secretory pathway in Mycobacterium tuberculosis H37Rv"Keystone Symposia. Tuberculosis: Integrating Host and Pathogen Biology, April 2-7, 2005, Whistler, Bristish Columbia, CanadaWiker, H. G."Predicting proteins exported through the general secretory pathway in Mycobacterium tuberculosis H37Rv"Fighting infection. Joint meeting: Society for General Microbiology UK; Society for Medical Microbiology Norway; Society forMicrobiology, Norway, Society for Virology, Norway; 27-30 september 2005; Radisson SAS Hotel, Bergen, NorwayCharlet, D., Mostowy, S., Alexander, D., Sit, L., Wiker H.G., Behr, M. A."Expression of Mycobacterium bovis antigenic proteins MPB70 and MPB83 is controlled by the alternate sigma factor sigK"Keystone Symposia. Tuberculosis: Integrating Host and Pathogen Biology, April 2-7, 2005, Whistler, Bristish Columbia, CanadaCharlet, D., Mostowy, S., Alexander, D., Sit, L., Wiker H.G., Behr, M. A."Expression of Mycobacterium bovis antigenic proteins MPB70 and MPB83 is controlled by the alternate sigma factor sigK"Fighting infection. Joint meeting: Society for General Microbiology UK; Society for Medical Microbiology Norway; Society forMicrobiology, Norway, Society for Virology, Norway; 27-30 september 2005; Radisson SAS Hotel, Bergen, Norway285