Bulletin 2009/49 - European Patent Office
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Bulletin 2009/49 - European Patent Office

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Bulletin 2009/49 - European Patent Office

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(C07D) I.1(1)<br />

(86) SE 2008/000045 21.01.2008<br />

(87) WO 2008/091195 2008/31 31.07.2008<br />

(30) 22.01.2007 US 885938 P<br />

(54) • NEUARTIGE HETEROARYL-SUBSTITU-<br />

IERTE IMIDAZO[1,2-A]-PYRIDINDERIVATE<br />

• NOVEL HETEROARYL SUBSTITUTED IMI-<br />

DAZO Ý1,2 -A¨PYRIDINE DERIVATIVES<br />

• NOUVEAUX DÉRIVÉS D'IMIDAZO Ý1,2-<br />

A¨PYRIDINE SUBSTITUÉS PAR HÉTÉROA-<br />

RYLE<br />

(71) AstraZeneca AB, 151 85 Södertälje, SE<br />

(72) VALLIN, Michaela, S-117 67 Stockholm, SE<br />

MALMSTRÖM, Jonas, S-151 85 Södertälje,<br />

SE<br />

PYRING, David, S-151 85 Södertälje, SE<br />

SLIVO, Can, S-151 85 Södertälje, SE<br />

WENSBO, David, S-203 13 Malmö, SE<br />

(51) C07D 471/04 (11) 2 125 801 A1*<br />

A61K 31/437 A61P 25/28<br />

(25) En (26) En<br />

(21) 08708724.3 (22) 05.02.2008<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

(86) EP 2008/051427 05.02.2008<br />

(87) WO 2008/095943 2008/33 14.08.2008<br />

(30) 06.02.2007 GB 0702259<br />

(54) • VERWENDUNG VON 7-AZAINDOLEN BEI<br />

DER INHIBIERUNG VON C-JUN-N-TERMI-<br />

NAL-KINASE<br />

• THE USE OF 7-AZAINDOLES IN THE<br />

INHIBITION OF C-JUN N-TERMINAL<br />

KINASE<br />

• UTILISATION DE 7-AZAINDOLES DANS<br />

L'INHIBITION DE C-JUN N-TERMINAL<br />

KINASE<br />

(71) Eisai R&D Management Co., Ltd., 6-10,<br />

Koishikawa 4-chome, Bunkyo-ku, Tokyo<br />

112-8088, JP<br />

(72) GRACZYK, Piotr Pawel, London WC1E 6BT,<br />

GB<br />

DIMOPOULOS, Paschalis, London WC1E<br />

6BT, GB<br />

FARTHING, Christopher Neil, London WC1E<br />

6BT, GB<br />

BHATIA, Gurpreet Singh, London WC1E 6BT,<br />

GB<br />

KHAN, Afzal, London WC1E 6BT, GB<br />

(74) Crooks, Elizabeth Caroline, et al, Kilburn &<br />

Strode LLP 20 Red Lion Street, London<br />

WC1R 4PJ, GB<br />

(51) C07D 471/04 (11) 2 125 802 A1*<br />

A61K 31/4375 A61L 2/16<br />

A61P 31/04<br />

(25) En (26) En<br />

(21) 08714623.9 (22) 15.02.2008<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

(86) CA 2008/000300 15.02.2008<br />

(87) WO 2008/098374 2008/34 21.08.2008<br />

(30) 16.02.2007 US 890319 P<br />

(54) • SALZE, PRODRUGS UND POLYMORPHE<br />

VON FAB-I-INHIBITOREN<br />

• SALTS, PRODRUGS AND POLYMORPHS<br />

OF FAB I INHIBITORS<br />

• SELS, PROMÉDICAMENTS ET POLYMOR-<br />

PHES D'INHIBITEURS DE FAB 1<br />

(71) Affinium Pharmaceuticals, Inc., 100 University<br />

Avenue 12th Floor, North Tower, Toronto,<br />

Ontario M5J 1V6, CA<br />

(72) PAULS, Henry, Oakville, Ontario L6L 5A4, CA<br />

RAMNAUTH, Jailall, Toronto, Ontario M9V<br />

5E6, CA<br />

Europäisches <strong>Patent</strong>blatt<br />

<strong>European</strong> <strong>Patent</strong> <strong>Bulletin</strong><br />

<strong>Bulletin</strong> européen des brevets<br />

(74) Adams, Harvey Vaughan John, et al, Mathys<br />

& Squire LLP 120 Holborn, London EC1N<br />

2SQ, GB<br />

(51) C07D 471/04 (11) 2 125 803 A1*<br />

A61K 31/437<br />

(25) Fr (26) Fr<br />

(21) 08775557.5 (22) 14.02.2008<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

(86) FR 2008/000197 14.02.2008<br />

(87) WO 2008/129152 2008/44 30.10.2008<br />

(30) 16.02.2007 FR 0701138<br />

(54) • PYRROLO-[2,3-B]-PYRIDIN-VERBINDUN-<br />

GEN, AZAINDOL-VERBINDUNGEN ZUR<br />

SYNTHESE DIESER PYRROLO-[2,3-B]-<br />

PYRIDIN-VERBINDUNGEN, VERFAHREN<br />

ZU IHRER HERSTELLUNG UND IHRE<br />

ANWENDUNG<br />

• PYRROLO[2,3-B]PYRIDINE COMPOUNDS,<br />

AZAINDOLE COMPOUNDS USED FOR<br />

SYNTHESIZING SAID PYRROLO[2,3-B]<br />

PYRIDINE COMPOUNDS, METHODS FOR<br />

THE PRODUCTION THEREOF, AND USES<br />

THEREOF<br />

• COMPOSES PYRROLO[2,3-B]PYRIDINE,<br />

COMPOSES AZAINDOLES UTILES DANS<br />

LA SYNTHESE DE CES COMPOSES PYR-<br />

ROLO[2,3-B]PYRIDINE, LEURS PROCE-<br />

DES DE FABRICATION ET LEURS<br />

UTILISATIONS<br />

(71) Centre National de la Recherche Scientifique,<br />

3, rue Michel Ange, 75016 Paris, FR<br />

Université Pierre et Marie Curie (Paris VI), 4,<br />

Place Jussieu Tour Centrale, 75252 Paris<br />

Cedex 05, FR<br />

UNIVERSITE CLAUDE BERNARD - LYON 1,<br />

43, boulevard du 11 novembre 1918, 69100<br />

Villeurbanne, FR<br />

(72) MEIJER, Laurent, F-29680 Roscoff, FR<br />

JOSEPH,Benoît, F-69100 Villeurbanne, FR<br />

LIGER, François, F-69100 Villeurbanne, FR<br />

MARQUET, Bernard, F-69300 Caluire, FR<br />

(74) Tanty, François, Nony & Associés 3, rue de<br />

Penthièvre, 75008 Paris, FR<br />

(51) C07D 471/04 (11) 2 125 804 A1*<br />

A61K 31/437 A61P 11/06<br />

A61P 37/08 A61P 9/12<br />

A61P 9/10 A61P 29/00<br />

A61P 3/10 A61P 37/00<br />

(25) En (26) En<br />

(21) 07846763.6 (22) 23.11.2007<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU LV MC MT NL PL PT<br />

RO SE SI SK TR<br />

AL BA HR MK RS<br />

(86) EP 2007/010162 23.11.2007<br />

(87) WO 2008/080461 2008/28 10.07.2008<br />

(30) 29.12.2006 ES 200603309<br />

(54) • ALS A2B-ADENOSINREZEPTORANTAGO-<br />

NISTEN GEEIGNETE 5-PHENYL-6-PYRI-<br />

DIN-4-YL-1,3-DIHYDRO-2H-IMIDAZO[4,5-<br />

B]PYRIDIN-2-ONDERIVATE<br />

• 5-PHENYL-6-PYRIDIN-4-YL-1,3-DIHY-<br />

DRO-2H-IMIDAZOÝ4,5-B¨PYRIDIN-2-ONE<br />

DERIVATIVES USEFUL AS A2B ADENO-<br />

SINE RECEPTOR ANTAGONISTS<br />

• DÉRIVÉS DE 5-PHÉNYL-6-PYRIDIN-4-YL-<br />

1,3-DIHYDRO-2H-IMIDAZOÝ4,5-B¨PYRI-<br />

DIN-2-ONE UTILISABLES EN TANT<br />

QU'ANTAGONISTES DU RÉCEPTEUR A2B<br />

DE L'ADÉNOSINE<br />

(71) Almirall, S.A., Ronda General Mitre 151,<br />

08022 Barcelona, ES<br />

(72) AIGUADE BOSCH, Jose, E-08025 Barcelona,<br />

ES<br />

190<br />

Anmeldungen<br />

Applications<br />

Demandes (<strong>49</strong>/<strong>2009</strong>) 02.12.<strong>2009</strong><br />

CARRANCO MORUNO, Ines, E-08690 Sta.<br />

Coloma de Cervello, ES<br />

VIDAL JUAN, Bernat, E-08396 St. Cebria de<br />

Vallalta, ES<br />

(74) Winkler, Andreas Fritz Ernst, Forrester &<br />

Boehmert Pettenkoferstrasse 20-22, 80336<br />

München, DE<br />

(51) C07D 471/04 (11) 2 125 805 A1*<br />

C07D 473/34 C07D 487/04<br />

C07D 519/00 A61K 31/437<br />

A61K 31/52 A61P 35/00<br />

(25) En (26) En<br />

(21) 07848736.0 (22) 20.12.2007<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU LV MC MT NL PL PT<br />

RO SE SI SK TR<br />

(86) GB 2007/050776 20.12.2007<br />

(87) WO 2008/075109 2008/26 26.06.2008<br />

(30) 21.12.2006 GB 0625668<br />

21.12.2006 US 871386 P<br />

25.10.2007 US 982633 P<br />

(54) • SUBSTITUIERTE PIPERIDINE MIT PRO-<br />

TEINKINASEHEMMENDER WIRKUNG<br />

• SUBSTITUTED PIPERIDINES HAVING<br />

PROTEIN KINASE INHIBITING ACTIVITY<br />

• PIPÉRIDINES SUBSTITUÉES AYANT UNE<br />

ACTIVITÉ INHIBANT LA PROTÉINE KINASE<br />

(71) Astex Therapeutics Limited, 436 Cambridge<br />

Science Park Milton Park Cambridge, Cambridgeshire<br />

CB4 0QA, GB<br />

The Institute of Cancer Research: Royal<br />

Cancer Hospital, 123 Old Brompton Road,<br />

London SW7 3RP, GB<br />

Cancer Research Technology Limited, Sardinia<br />

House Sardinia Street London, Greater<br />

London WC2A 3NL, GB<br />

(72) WOODHEAD, Steven John, Cambridge Cambridgeshire<br />

CB4 0QA, GB<br />

FREDERICKSON, Martyn, Cambridge Cambridgeshire<br />

CB4 0QA, GB<br />

HAMLETT, Christopher, Cambridge Cambridgeshire<br />

CB4 0QA, GB<br />

WOODHEAD, Andrew James, Cambridge<br />

Cambridgeshire CB4 0QA, GB<br />

VERDONK, Marinus Leendert, Cambridge<br />

Cambridgeshire CB4 0QA, GB<br />

SORE, Hannah Fiona, Cambridge Cambridgeshire<br />

CB4 0QA, GB<br />

WALKER, David Winter, Cambridge Cambridgeshire<br />

CB4 0QA, GB<br />

BLURTON, Peter, Welwyn Garden City AS8<br />

7SB, GB<br />

COLLINS, Ian, Sutton Surrey SM2 5NG, GB<br />

CHEUNG, Kwai Ming, Sutton Surrey SM2<br />

5NG, GB<br />

CALDWELL, John, Sutton Surrey SM2 5NG,<br />

GB<br />

DA FONSECA McHARDY, Tatiana Faria,<br />

Sutton Surrey SM2 5NG, GB<br />

LUKE, Richard William Arthur, Macclesfield<br />

Cheshire SK10 4TG, GB<br />

MATUSIAK, Zbigniew Stanley, Macclesfield<br />

Cheshire SK10 4TG, GB<br />

LEACH, Andrew, Macclesfield Cheshire SK10<br />

4TG, GB<br />

MORRIS, Jeffrey James, Macclesfield Cheshire<br />

SK10 4TG, GB<br />

(74) Brearley, Helen Rebecca, Elkington and Fife<br />

LLP Prospect House 8 Pembroke Road,<br />

Sevenoaks Kent TN13 1XR, GB<br />

(51) C07D 471/04 (11) 2 125 806 A1*<br />

A61K 31/437 A61P 3/10<br />

(25) En (26) En<br />

(21) 078<strong>49</strong>005.9 (22) 03.12.2007<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU LV MC MT NL PL PT<br />

RO SE SI SK TR

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