Literature review for - Flourish Paediatrics

descriptive)
RESULTS
Outcome
EXTERNAL
VALIDITY
Generalisability
Applicability
Comments
Conclusion
9 studies rated "good", 10 as "fair" and 4 as "poor". Better studies had higher risk for bottle feeding. OR for studies ranged
from 0.56 to 5.95. 19 studies had a protective effect for breastfeeding, 1 had no effect and 3 showed a negative effect. Most
of the studies were protective. The pooled OR for 23 studies was 2.11 (95% CI: 1.66 - 2.68). For higher quality studies only
OR = 2.24 ("good" studies) and 2.32 (studies in last 10 years). 9 studies included data on partial breastfeeding and 7 had
enough data to estimate SIDs risk; 4 showed a dose response for increasing use of formula feeding but none had sufficient
power to demonstrate statistically significant difference for partial versus no breastfeeding.
Death from SIDS
Yes
Yes
Data includes Australian studies. The meta-analysis suggested breastfeeding conveys a 50% reduced risk of SIDs
Breastfeeding should be strongly encouraged, independent of SIDs and the evidence for SIDs protection is imperfect due to
confounding.
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