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Literature review for - Flourish Paediatrics

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Quality P P 0 P<br />

Results<br />

An infant was exposed to<br />

cow’s milk in 9.9% (69/696)<br />

of the study population by the<br />

6-month follow-up, by 12<br />

months 50.7% (338/696) had<br />

ever received cow’s milk.<br />

No association between cow’s<br />

milk consumption (between 6<br />

and 12 months) and childhood<br />

asthma was found <strong>for</strong> the<br />

concurrent effects model OR =<br />

0.81 (0.55, 1.20).<br />

In examining food and<br />

nutrient intake by feeding<br />

group, breast-milk intake was<br />

higher in the BM than in<br />

the BCM group (761 ±231 vs.<br />

464 ±352 mL/d, respectively,<br />

P = 0.001).<br />

Cow’s milk volume, was<br />

higher in the BCM than in<br />

BM group (232 ± 227 mL/d<br />

25 ± 60 p= 0.001).<br />

The infants classified as BM<br />

consumed 25 ± 60 mL/d of<br />

cow’s milk on the day of food<br />

weighing. In the BCM group,<br />

5 infants had an intake of<br />

cow’s milk of 0 mL/d on the<br />

day that food weighing took<br />

place.<br />

MOEE was 1672 ± 175 kJ/d<br />

in BM compared with 1858<br />

± 210 kJ/d in BCM infants (P<br />

< 0.001)<br />

If infants were classified on<br />

the basis of their actual intake<br />

of cow’s milk on the day of<br />

Their median iron intakes<br />

ranged from 4.3 mg (at 12<br />

months) to 7.0 mg (at 9<br />

months) per day and were<br />

below estimated<br />

requirements at all ages.<br />

At 9, 12 and 18 months of<br />

age, 7% (n = 4) of the<br />

infants had iron deficiency<br />

anaemia.<br />

More than two-thirds<br />

(69%) were being given<br />

cow’s milk as a beverage<br />

be<strong>for</strong>e the age of 12<br />

months.<br />

The mean age of<br />

introduction of cow’s milk<br />

as a beverage was 40<br />

weeks <strong>for</strong> those who<br />

introduced cow’s milk<br />

be<strong>for</strong>e 12 months.<br />

cohort 2 no results are<br />

presented.<br />

At 12 months of age 41%<br />

of infants were iron<br />

depleted, 20% were iron<br />

deficient, and 2.7 % had<br />

IDA.<br />

It was demonstrated by<br />

regression analysis that Fe<br />

status was negatively<br />

associated with cow’s milk<br />

consumption at 9–12<br />

months (significant at<br />

>460 g/d)<br />

All Fe status indices,<br />

except Hb, differed<br />

significantly between the<br />

children receiving<br />

500 ml<br />

cow’s milk daily (mean<br />

SF= 9.7 µg/L, mean<br />

MCV=73.1 fl).<br />

Fe-deficient 1-year-olds<br />

(n=10) had lower fine<br />

383

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