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Literature review for - Flourish Paediatrics

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had a significantly reduced risk of<br />

one or more episodes of<br />

gastrointestinal infection in the first<br />

12 months of life (RR 0.67 (95% CI<br />

0.46- 0.97) (outcome 47), which was<br />

maintained in a multivariate mixed<br />

model controlling <strong>for</strong> geographic<br />

origin, urban versus rural location,<br />

maternal education, and number of<br />

siblings in the household (adjusted<br />

OR 0.61 (95% CI 0.41 - 0.93).No<br />

significant reduction in risk was<br />

observed <strong>for</strong> hospitalization <strong>for</strong><br />

gastrointestinal infection, however<br />

RR 0.79 (95% CI 0.42-1.49)<br />

(outcome 48). In the abovementioned<br />

Australian cohort study,<br />

Oddy 1999 found no significant<br />

reduction of risk <strong>for</strong> one or more<br />

episodes of upper respiratory tract<br />

infection (outcome49) in the EBF<br />

group RR 1.07 (95% CI 0.96-1.20).<br />

Neither Oddy 1999 nor Kramer<br />

2000a found a significantly reduced<br />

risk of two or more such episodes<br />

pooled RR 0.91 (95% CI 0.82 -1.02)<br />

(outcome 50). Nor did Oddy 1999<br />

find a significant reduction in risk of<br />

4 or more episodes of upper<br />

respiratory infection RR 0.82 (95%<br />

CI 0.52 - 1.29) (outcome 51) or of<br />

one or more episodes of lower<br />

549

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