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Literature review for - Flourish Paediatrics

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descriptive)<br />

RESULTS<br />

Outcome<br />

EXTERNAL<br />

VALIDITY<br />

Generalisability<br />

Applicability<br />

Comments<br />

Conclusion<br />

Odds ratios in the range of 1.2 to 1.5 <strong>for</strong> increased risk of asthma and atopic disease all show increased risk when not<br />

breastfed. Authors quote a previously published meta-analysis of 9 studies that showed that children breastfed <strong>for</strong> at least 3<br />

months were significantly protected against development of asthma, OR= 0.80 and other meta analyses with a similar<br />

protective effect (26%-30%) <strong>for</strong> exclusive breastfeeding during the first 3 months from developing asthma, allergic rhinitis<br />

and atopic eczema.<br />

y<br />

y<br />

From the studies that met the strict criteria <strong>for</strong> breastfeeding and atopic disease, all demonstrated a protective effect of<br />

breast-milk feeding or conversely, a risk of <strong>for</strong>mula feeding. However, the continuing protective effect of breastfeeding on<br />

asthma and atopy later in adolescence and adulthood has yet to be confirmed in larger longitudinal studies. Given the many<br />

benefits conferred by breast-milk, breastfeeding should continue to be promoted as the preferred infant feeding method <strong>for</strong><br />

the first 6 months and up to two years, as recommended by WHO.<br />

525

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