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Literature review for - Flourish Paediatrics

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infants with low z-scores provided low<br />

statistical power to detects such<br />

differences. RRs (and 95% CIs) <strong>for</strong> low<br />

weight-<strong>for</strong>-age were 0.92 (0.04 -19.04)<br />

at 6 mo, 1.52 (0.16-14.62) at 9 mo and<br />

1.15 (0.13- 10.31) at 12 mo (outcomes<br />

16 to18). For length-<strong>for</strong>-age, the<br />

corresponding figures were 1.53 (0.84 -<br />

.78) at 6 mo, 1.46 (0.80-2.64) at 9 mo,<br />

and 0.66 (0.23 -1.87) at 12 mo<br />

(outcomes 19 to 21). For weight -<strong>for</strong>length,<br />

the figures were 0.31 (0.02-<br />

5.34) at 6 mo, 1.14 (0.24- 5.37) at 9 mo,<br />

and 1.15 (0.13-10.31) at 12 mo<br />

(outcomes 22 to 24). The Belarussian<br />

study also provided data on head<br />

circumference. No significant<br />

differences were observed at 6 mo<br />

(difference -1.0 (95% CI -2.3 - +0.3)<br />

mm) (outcome 25) or 9 mo (+0.7 (95%<br />

CI -0.6 - +2.0) mm) (outcome 26), but<br />

the EBF group had a slightly but<br />

significantly larger circumference at 12<br />

mo (outcome 27): difference = +1.9<br />

(95% CI +0.6 - +3.2) mm. Heinig 1993<br />

reported nearly identical sleeping time<br />

(729 versus 728 minutes/day) in the two<br />

groups (outcome 28). Akeson 1996a<br />

reported similar total amino acid and<br />

essential amino acid concentrations at 6<br />

mo of age in the two feeding groups<br />

(outcomes 29 and 30). Both Kramer<br />

506

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