Literature review for - Flourish Paediatrics

When restricted to those without
family history, OR 0.84 (95%CI
0.59 - 1.19)
Authors’ conclusion: “There is a
substantial protective effect of
breastfeeding against atopic
dermatitis in children with a
family history of atopy.”
history history
4 months 0.79
(0.43,1.44)
1.03
(0.65,1.63)
Partial
breastfeeding
6 months 0.91
(0.45,1.91)
Asthma
Exclusive
breastfeeding
4 months 0.62
(0.17,2.05)
Partial
breastfeeding
6 months 0.38 0.80
(0.11,1.37) (0.30,2.39)
*Adjustment for maternal age, indoor
domestic pets, family income, maternal
and paternal education, maternal smoking
during pregnancy, baby’s sex, baby’s
older siblings, household smoking in
same room as infant, and time of delivery
before third survey..
and without
those factors as confounders was
performed.
There was a significantly higher
proportion of complete breastfeeding
among those with greater risk of allergic
diseases (presence of family history,
either eczema or wheeze within 6
months after birth, or FA in infancy).
Therefore, our multivariate analysis
included these risks as confounding
factors, and we found that the
promoting effects of breastfeeding on
AD and FA disappeared. In conclusion,
our data clearly showed the inhibitory
effect of breastfeeding on the
prevalence of BA at school age.
The apparent promoting effect of
breastfeeding on the prevalence of AD
and FA is most likely because of
reverse causation.
Effect on risk Decrease where family history of
atopy
Breastfeeding not related to asthma or
wheezing
Breastfeeding not related to asthma or
wheezing
Clinical 1 1 1
importance
Clinical 1 0 0
403