Literature review for - Flourish Paediatrics

Clinical relevance
[10]
1. Evidence of an effect on patientrelevant
outcomes, including benefits
Evidence of an effect on patientrelevant
outcomes, including benefits
3. No clinically important effects.
Generalisability y y y
Applicability y y y
Comments
First meta-analysis of RCTs in
children and infants. Relatively small
BP reductions, but clinically
significant if preventive of BP
increases with age into adulthood.
Non-systematic review. Na
reduction lowers BP (No estimate of
effect given). No trials cited showed
increases in BP with a restriction.
Not systematic review, but due to
limited studies in infants and children
was included. Further studies needed to
assess whether Na restriction in early
childhood result in beneficial BP
reductions later in life.
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