Literature review for - Flourish Paediatrics

Studies used to make evidence statement for the prevalence of postnatal depression
Reference Gavin & Gaynes (2005) (Jones, Scott et al. 2010) O’Hara & Swain (1996)
Type of study SLR Cohort study Meta-analysis
Level of evidence I (aetiology) II (aetiology) I (aetiology)
Definition of
breastfeeding
Not defined Not defined Not defined
Intervention/
comparator
Prevalence of postnatal depression
N Sample sizes of studies ranged from 54 -
4,964
Population/study
information
Searched databases for articles published
in English between 1980- 2004.
Review included cross sectional studies,
cohort studies and case-control from
developed countries that assessed women
for depression during pregnancy or the
first year postpartum with a structured
clinical interview.
846 articles originally identified. 109
articles were reviewed, 28 met the
inclusion criteria
Maternal postnatal depression (EPDS
score ≥ 13) and later child growth
faltering or overweight
929 children. 1678 were originally
recruited. Follow up at 6 months was
95% (n= 879)
Women and their children
participating in a European
multicenter RCT were included at
a median age of 14 days. Participants
in the European multicenter RCT
were recruited at 11 study sites in
five countries (Belgium; Germany;
Italy; Poland; Spain).
At visits 2, 3 and 6 months after
delivery, the mothers were asked to
complete the Edinburgh postnatal
depression scale (EPDS)
EPDS scores of 13 and above at any
time were defined as maternal
depression.
Prevalence of postnatal depression
12,810 (from 59 studies)
Searched for studies that examined
the relationship between postpartum
depression and a possible risk factor.
Investigations were included if they
met the following criteria: (a)
reported statistical relationship
between variable of interest and
postpartum depression (b) variable of
interest assessed during either
pregnancy or delivery; (c) subjects
recruited through random or quasirandom
sampling techniques; (d)
depression assessed after at least two
weeks postpartum (e) postpartum
depression assessed using a validated
or standardized measure.
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