Literature review for - Flourish Paediatrics

Additional studies used to update evidence statement for Breastfeeding and SIDS
Reference Venneman 2009 Pediatrics Ip 2007 Technology Assessment
Type of study Case control SLR
Level of evidence III I
Definition of EBF breastmilk only, with no extra bottle of milk Ever Breastfeeding (ABF)
breastfeeding formula or solids given at any time of the day.
Partial breastfeeding (ABF) was defined as any bottle
feeding (milk formula) or solids given in addition to
breast milk.
Not breastfed was defined as no breast milk.
Intervention
Not Breastfed
Comparator
N
333 infants who died from SIDS and 998 agematched
controls
769 cases of SIDS and 2,681 controls.
Population/study
information
German Study of Sudden Infant Death
Seven studies where SIDS was clearly defined with
autopsy evidence
Developed Countries
Quality P P
Results
Breastfeeding reduced risk of SIDS
ABF at 2 weeks OR 0.43 (0.27,0.69)
Breastfeeding reduced risk of SIDS
ABF OR 0.64 ( 0 .51, 0 .81)
EBF at 4 weeks OR 0.48 (0.28,0.82)
ABF at 4 weeks OR 0.48 (0.21,1.10)
Effect on risk Negative Negative
Clinical importance 1 1
Clinical relevance 1 1
Generalisability Y Y
Applicability Y Y
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