Literature review for - Flourish Paediatrics

7 yrs, and being small for
gestational age and being above 2
standard deviations in height at age
18-25 yrs.
N [5] 325,412 7223 at baseline
2934 for analysis
Population/study Infants and children
Children born 1981-1984 at one of two
information [6]
major obstetric hospitals in Brisbane.
(Mater-University of Queensland Study
of Pregnancy). Followed for 14 yrs.
2103 at baseline
1944 at year 5
Random sample of children born in
Quebec, Canada in 1998. 48.9% female.
5 yr follow-up.
Quality [7] P P P
Results [8] All but 2 studies reported a positive
association between rapid growth –
regardless of definition – and
occurrence of overweight, obesity,
or greater adiposity measures,
regardless of age at which
measured. No summary statistic is
reported. Examples of individual
data: for every 100 g of monthly
weight gain in first 4 mo of life,
there was a 38% increase (P95th percentile) at age
4.5 yrs: 4th quintile adj OR 1.8 (95% CI
1.0-3.5), 5th quintile adj OR 3.9 (95% IC
1.9-7.9).
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