Literature review for - Flourish Paediatrics

Results
Any breastfeeding reduced
the risk of obesity in
childhood. Adjusted OR
0.78 (0.71,0.85)
Breastfeeding vs. not
breastfeeding reduced the
risk of obesity in later life.
Pooled OR 0.78 (0.72,0.84)
Breastfeeding duration was
inversely and linearly
associated with the risk of
being overweight.
Regression coefficient 0.94
(0.89, 0.98) Each month of
breastfeeding up until 9
months was found to be
associated
with a 4 percent decrease in
risk up. OR
0.96/month of
breastfeeding, (0.94, 0.98).
Effect on risk Negative Negative Negative Negative
Clinical 1 1 1 1
importance
Clinical 1 1 1 1
relevance
Generalisability Y Y Y Y
Applicability Y Y Y Y
Emphasized how
sensitivity analyses carried
out by Arenz and Owen
showed a continuous
reduction of the effect of
breastfeeding on
overweight and obesity
when more factors were
accounted for in the
analysis.
Reference Owen et al. 2005 (Ped) Owen et al. 2005 (Am J Clin Monasta et al. 2010 Kramer et al. 2007
Nutr)
Type of study SLR & meta-analysis SLR & meta-analysis SLR Randomized trial
Level of evidence I (aetiology) I (aetiology) I (aetiology) II (intervention)
Definition of
breastfeeding
Definitions of breastfeeding
differed across reviews
Followed WHO
definitions
Few studies stated their
definition of exclusive
breastfeeding therefore the
Few studies stated their
definition of exclusive
breastfeeding therefore the
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