Literature review for - Flourish Paediatrics

Table 14.4 Studies used to make evidence statements for sugars and dental disease
Reference [1] Levy et al. 2003 Marshall et al. 2003 Ruottinen et al. 2004 Warren et al. 2009
Type of study Cohort Cohort Cohort Cohort
[2]
Level of III-2 III-2 III-2 III-2
evidence [3]
Intervention/
comparator [4]
Dietary intake was
partitioned into eleven
broad categories: water,
formula, breast milk, cow's
milk, juices and juice
drinks, non-juice
beverages as purchased,
beverages made from
frozen concentrates,
beverages made from
powdered concentrates,
ready-to-feed baby food,
infant cereal made from
powder, and other foods
made with water (Jell-O®,
soup, etc.).
Dietary intake was
partitioned into eleven
broad categories: water,
formula, breast milk, cow's
milk, juices and juice
drinks, non-juice beverages
as purchased, beverages
made from frozen
concentrates, beverages
made from powdered
concentrates, ready-to-feed
baby food, infant cereal
made from powder, and
other foods made with water
(Jell-O®, soup, etc.).
Mean±SD in high sucrose
group 52.6± 13.1 g/d range
25.7-82.8 g/d; Low sucrose
group 32.5± 18.5 g/d range
5.3-81.6 g/d
N [5] 291 children 396 children 66 children 128 infants
Population/
study
information [6]
Finnish children
mean age 10 years (range 8-
11)
US Children
6 weeks - 4 years old,
mean age 5.17 years at
dental exam;
53.3% female; 99% white
US Children
6 weeks - 7 years old, mean
age 3.2 years at dental
exam;
51.3% female; 97.2% white
Quality [7] O P O O
Results [8] Frequency of sugar
sweetened beverage
consumption and dental
caries OR = 1.26, P=0.21;
Frequency of soda pop
consumption and dental
caries OR 2.2 (95% CI 1.4-
3.6, P=0.05) Frequency of
Decayed, missing and filled
teeth in high vs. low sucrose
intake group - mean±SD
3.9±3.9 in high sucrose and
Dietary intake was partitioned
into eleven broad categories:
water, formula, breast milk,
cow's milk, juices and juice
drinks, non-juice beverages
as purchased, beverages made
from frozen concentrates,
beverages made from
powdered concentrates,
ready-to-feed baby food,
infant cereal made from
powder, and other foods
made with water (Jell-O®,
soup, etc.).
Us infants
age range 6-24 months; mean
age 12.6 months; 58% male;
75% Caucasian
Sugar sweetened beverage
consumption and caries OR
3.04 (95% CI 1.07–8.64, P=
0.04)
469