Literature review for - Flourish Paediatrics

Level of evidence I (a) I (aetiology) I (a)
Definition of Not stated Not stated
breastfeeding
Intervention/
comparator
Antibiotic therapy vs alternative
therapies for the treatment of mastitis
N 125 women 960 women
Population/study
information
Searched for RCTs or quasi-RCTs
11 articles initially found
2 trials met inclusion criteria.
One study compared two different
antibiotics (amoxicillin vs.
cephradine)
The second study compared no
treatment, breast emptying,
and antibiotic therapy
preventive interventions for mastitis
including breastfeeding education,
taking antibiotic medication, topical
ointments and anti-secretory factor
cereal on the incidence and recurrence
of mastitis and breastfeeding outcomes
(duration, maternal satisfaction,
maternal confidence)
Searched a variety of databases from
date they commenced to 2009 on
interventions for mastitis. No language
restrictions were applied.
The search strategy protocol generated
1029 article ’hits’. After screening
titles and abstracts, 38 articles
remained, 5 of which met the inclusion
criteria.
The review included RCTs of
interventions for preventing mastitis in
postpartum breastfeeding women
Most of the included studies were of
poor study quality and design. Sample
size of studies ranged from 10-615
Breast disease
16 studies on recommendations for the
diagnosis and therapy of breast diseases
during lactation
Authors note most studies had rather
low evidence levels
208