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Literature review for - Flourish Paediatrics

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weight loss).Comparison one:<br />

controlled trials of exclusive vs.<br />

mixed breastfeeding <strong>for</strong> 4-6 months,<br />

developing countries and<br />

Comparison two: observational<br />

studies of exclusive versus mixed<br />

breastfeeding <strong>for</strong> 3-7 months,<br />

developing countries and<br />

Comparison three: observational<br />

studies of prolonged (more than 6<br />

months) exclusive versus mixed<br />

breastfeeding, developing countries<br />

are not relevant to Australia.<br />

Comparison 4 is relevant to the<br />

Australian population: Observational<br />

studies of exclusive versus mixed<br />

breastfeeding <strong>for</strong> 3-7 months in<br />

developed countries. Studies were<br />

heterogeneous with a WMD of -<br />

12.45 (95% CI -23.46 - -1.44) g per<br />

month & should be interpreted with<br />

caution, although even the lower<br />

95% confidence limit is compatible<br />

with a lower weight gain in the EBF<br />

group. Given the large weight gains<br />

in both groups in the Belarussian<br />

study, the higher gain in the MBF<br />

group is not necessarily a beneficial<br />

outcome. Heinig 1993 and Kramer<br />

2000a also reported on weight gain<br />

between six and nine months<br />

(outcome two) (significant<br />

breastfeeding' with the RR <strong>for</strong> stopping<br />

any breastfeeding be<strong>for</strong>e 6 months being<br />

0.91 (95% CI 0.86-0.96). All <strong>for</strong>ms of<br />

support affected the duration of exclusive<br />

breastfeeding more strongly than the<br />

likelihood of any breastfeeding RR 0.81<br />

(CI 0.74-0.89). Lay and professional<br />

support extended breastfeeding duration<br />

RR be<strong>for</strong>e 4-6 weeks 0.65 (CI 0.51-0.82);<br />

RR be<strong>for</strong>e 2 months 0.74 (CI 0.66-0.83).<br />

Further <strong>review</strong>s reported that with<br />

individual counselling the OR of<br />

exclusive breastfeeding were increased in<br />

the neonatal period (15 studies; OR 3.45<br />

(95% CI 2.2-5.42) p

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