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Literature review for - Flourish Paediatrics

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until at least 12 mo (a criterion <strong>for</strong><br />

selection into the Pisacane 1995<br />

study).Kramer 2000a recorded only one<br />

and two deaths (outcome 46) among the<br />

621 and 2862 Belarussian infants in the<br />

EBF and MBF groups, respectively (RR<br />

2.30 (95% CI 0.21- 25.37). The EBF<br />

had a significantly reduced risk of one<br />

or more episodes of gastrointestinal<br />

infection in the first 12 mo of life RR<br />

0.67 (95% CI 0.46 - 0.97) (outcome 47),<br />

which was maintained in a multivariate<br />

mixed model controlling <strong>for</strong> geographic<br />

origin, urban vs rural location, maternal<br />

education, and number of siblings in the<br />

household adjusted OR 0.61 (95% CI<br />

0.41- 0.93).No significant reduction in<br />

risk was observed <strong>for</strong> hospitalization <strong>for</strong><br />

gastrointestinal infection, however RR<br />

0.79 (95% CI 0.42-.49) (outcome 48).<br />

In the above-mentioned Australian<br />

cohort study, Oddy 1999 found no<br />

significant reduction of risk <strong>for</strong> one or<br />

more episodes of upper respiratory tract<br />

infection (outcome49) in the EBF group<br />

RR 1.07 (95% CI 0.96- 1.20). Neither<br />

Oddy 1999 nor Kramer 2000a found a<br />

significantly reduced risk of two or<br />

more such episodes pooled RR 0.91<br />

(95% CI 0.82 -1.02) (outcome 50). Nor<br />

did Oddy 1999 find a significant<br />

reduction in risk of 4 or more episodes<br />

509

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