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Literature review for - Flourish Paediatrics

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development<br />

of obesity later in life.<br />

Clinical 1 1 1 1<br />

importance<br />

Clinical 1 1 1 1<br />

relevance<br />

Generalisability Y- Europe Y-Brazil Y- NZ Y- Iceland<br />

Applicability Y-Europe Y-Brazil Y-NZ Y- Iceland<br />

Reference Zielger et al. 1999 Larnkjaer et al. 2009 Lehmann et al. 1992 Oti-Boateng et al. 1998<br />

Type of study Non-randomized controlled RCT Cohort Cross-sectional<br />

trial<br />

Level of evidence III-2 (intervention) II (intervention) II (aetiology) IV ( aetiology)<br />

Definition of<br />

breastfeeding<br />

Poorly defined<br />

Intervention/<br />

comparator<br />

N<br />

Cow’s milk feeding on stool<br />

Hb concentration<br />

62 infants completed the study.<br />

68 initially enrolled (92%)<br />

Whole cow’s milk (WM) vs.<br />

infant <strong>for</strong>mula as the primary<br />

milk source <strong>for</strong> 3 months on<br />

growth and insulin-like<br />

growth factor I (IGF-I) from<br />

9 to 12 months of age.<br />

94 infants initially included.<br />

Follow up at 3 months was 83<br />

infants (88%)<br />

risk factors <strong>for</strong> prevalence<br />

of iron deficiency anaemia<br />

(IDA)<br />

218 mother-infant pairs.<br />

(299 mother-infant pairs<br />

eligible)<br />

Cow’s milk intake during<br />

6-12 months of age on iron<br />

status.<br />

234 children. (325<br />

approached)<br />

385

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