Literature review for - Flourish Paediatrics

(2/23 studies were from Australia/New
Zealand)
Quality P P P
Results
Breastfed siblings were less likely to
have a BMI > 85th percentile in
childhood or adolescence compared to
their non-breastfed infant
AOR = 0.42
Breastfeeding is associated with a
decreased risk of overweight/obesity
in children later life, compared to
formula-feeding. OR = 0.75
(0.71,0.79)
The breastfed sibling had an
adolescent BMI that was 0.39 std dev
lower than his or her siblin
The pooled odds ratio shifted towards
no effect in Australia/New Zealand
studies OR =1.06 (0.88,1.29)
Effect on risk Negative Negative Negative
Clinical 1 1 1
importance
Clinical 1 1 1
relevance
Generalisability Y ? Y as meta-analyses showed no effect Y
in Aus studies
Applicability Y ? Y as meta-analyses showed no effect
in Aus studies
Y
Observational studies show a negative
association between any breastfeeding
and obesity in childhood or adulthood.
Observational studies show a positive
association between rapid infancy
weight gain and obesity in childhood or
adulthood.
Limited experimental evidence of
causal relationship between any
breastfeeding and obesity risk.
References used in body of evidence tables: (Arenz, Ruckerl et al. 2004; Harder, Bergmann et al. 2005; Owen, Martin et al. 2005; Owen, Martin
et al. 2005; Plagemann and Harder 2005; Oddy 2006; Horta, Bahl et al. 2007; Ip, Chung et al. 2007; Kramer, Matush et al. 2007; Singhal and
Lanigan 2007; Smith 2007; Stettler 2007; Metzger and McDade 2010; Monasta, Batty et al. 2010)
433