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Literature review for - Flourish Paediatrics

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Studies used to determine the risk factors associated with postnatal depression<br />

Reference Beck (2001) (<strong>review</strong>ed in Robertson et O’Hara & Swain (1996) (<strong>review</strong>ed Robertson et al. (2004)<br />

al. SLR adjacent)<br />

in Robertson et al. SLR adjacent)<br />

Type of study Meta-analysis Meta-analysis SLR<br />

Level of evidence I (aetiology) I (aetiology) I (aetiology)<br />

Definition of<br />

breastfeeding<br />

Varied between studies in analysis Varied between studies in analysis Varied between studies in analysis<br />

Intervention/<br />

comparator<br />

postpartum depression predictors<br />

Relationship between postnatal<br />

depression and a variety of nonbiological/hormonal<br />

risk<br />

factors<br />

N > 2692 12,810 (from 59 studies) ≈24,000<br />

Population/study<br />

in<strong>for</strong>mation<br />

On-line databases were searched <strong>for</strong> the<br />

10-year period between 1990-2000<br />

A total of 107 potential studies were<br />

located. 84 studies met the sample<br />

criteria. 54 (64%) of the studies were<br />

journal articles, 28 (34%) were<br />

unpublished dissertations, and two<br />

studies were unpublished master’s theses.<br />

44 studies (52%), took place in the<br />

United States, 11 (13%) in Canada, 7<br />

(8%) in the United Kingdom, 3 (4%)<br />

in New Zealand, two each in Australia,<br />

South Africa, Ireland, and France and one<br />

each in Japan, Belgium, Portugal, United<br />

Arab, Israel, Switzerland, Brazil, China,<br />

Nigeria, Netherlands, and Finland.<br />

Searched <strong>for</strong> studies that examined<br />

the relationship between postpartum<br />

depression and a possible risk factor.<br />

Investigations were included if they<br />

met the following criteria: (a)<br />

reported statistical relationship<br />

between variable of interest and<br />

postpartum depression (b) variable of<br />

interest assessed during either<br />

pregnancy or delivery; (c) subjects<br />

recruited through random or quasirandom<br />

sampling techniques; (d)<br />

depression assessed after at least two<br />

weeks postpartum (e) postpartum<br />

depression assessed using a validated<br />

or standardized measure.<br />

59 studies were eligible<br />

postpartum depression predictors<br />

19 databases relating to the medical,<br />

psychological, and social science<br />

literature were searched using specific<br />

inclusion criteria and search terms, in<br />

order to identify studies examining<br />

antenatal risk factors <strong>for</strong> postpartum<br />

depression.<br />

The research studies were of human<br />

subjects, empirical, peer-<strong>review</strong>ed,<br />

and published in English between<br />

1990 and 2002 (excluding seminal<br />

studies prior to these dates)<br />

2 major meta-analyses (Ohara &<br />

Swain and Beck in columns adjacent)<br />

conducted on over 14,000 subjects, as<br />

well as newer subsequent large-scale<br />

234

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